(Q39587315)

13 September 2017

Unspliced XBP1 controls autophagy through FoxO1. (English)

1 reference

13 September 2017

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Rene L Vidal

1

1 reference

PMCID

3616432

13 September 2017

Claudio Hetz

series ordinal

2

1 reference

13 September 2017

22 January 2013

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13 September 2017

1 reference

13 September 2017

23

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13 September 2017

4

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13 September 2017

463-464

1 reference

https://scigraph.springernature.com/pub.10.1038/cr.2013.9

13 September 2017

0 references

cites work

XBP-1u suppresses autophagy by promoting the degradation of FoxO1 in cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616432

Targeting the UPR transcription factor XBP1 protects against Huntington's disease through the regulation of FoxO1 and autophagy

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616432

The unfolded protein response: controlling cell fate decisions under ER stress and beyond

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616432

BAX inhibitor-1 regulates autophagy by controlling the IRE1α branch of the unfolded protein response.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616432

JNK regulates FoxO-dependent autophagy in neurons

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616432

Regulation of glucose homeostasis through a XBP-1-FoxO1 interaction

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616432

Translational pausing ensures membrane targeting and cytoplasmic splicing of XBP1u mRNA.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616432

Cytosolic FoxO1 is essential for the induction of autophagy and tumour suppressor activity

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616432

XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616432

Autophagy is activated for cell survival after endoplasmic reticulum stress

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616432

pXBP1(U) encoded in XBP1 pre-mRNA negatively regulates unfolded protein response activator pXBP1(S) in mammalian ER stress response

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616432

IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616432

Direct proteasome binding and subsequent degradation of unspliced XBP-1 prevent its intracellular aggregation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616432

Cotranslational targeting of XBP1 protein to the membrane promotes cytoplasmic splicing of its own mRNA.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616432

Expression and splicing of the unfolded protein response gene XBP-1 are significantly associated with clinical outcome of endocrine-treated breast cancer

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616432

21 August 2018

Identifiers

DOI

10.1038/CR.2013.9

1 reference

13 September 2017

1 reference

13 September 2017

1 reference

PMCID

3616432