(Q29615499)

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=22251901

30 April 2017

author name string

Hetz C

series ordinal

1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=22251901

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=22251901

30 April 2017

language of work or name

1 reference

30 April 2017

publication date

18 January 2012

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=22251901

Nature Reviews Molecular Cell Biology

30 April 2017

published in

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=22251901

30 April 2017

volume

13

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=22251901

30 April 2017

issue

2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=22251901

30 April 2017

page(s)

89-102

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=22251901

Signal integration in the endoplasmic reticulum unfolded protein response

30 April 2017

cites work

1 reference

The presence of malfolded proteins in the endoplasmic reticulum signals the induction of glucose-regulated proteins

31 March 2020

1 reference

The mammalian unfolded protein response

31 March 2020

1 reference

The unfolded protein response: integrating stress signals through the stress sensor IRE1α

31 March 2020

1 reference

Modulating stress responses by the UPRosome: a matter of life and death

31 March 2020

1 reference

Regulation of basal cellular physiology by the homeostatic unfolded protein response

31 March 2020

1 reference

Regulated translation initiation controls stress-induced gene expression in mammalian cells

31 March 2020

1 reference

IRE1alpha kinase activation modes control alternate endoribonuclease outputs to determine divergent cell fates.

31 March 2020

1 reference

Regulated Ire1-dependent decay of messenger RNAs in mammalian cells

31 March 2020

1 reference

Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response.

31 March 2020

1 reference

Autophagy and the integrated stress response

31 March 2020

1 reference

Substrate-specific translocational attenuation during ER stress defines a pre-emptive quality control pathway

31 March 2020

1 reference

Cotranslocational degradation protects the stressed endoplasmic reticulum from protein overload

31 March 2020

1 reference

The unfolded protein response: from stress pathway to homeostatic regulation

31 March 2020

1 reference

IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA

31 March 2020

1 reference

IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response

31 March 2020

1 reference

XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor

31 March 2020

1 reference

XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response

31 March 2020

1 reference

XBP1 controls diverse cell type- and condition-specific transcriptional regulatory networks

31 March 2020

1 reference

The signalling from endoplasmic reticulum-resident bZIP transcription factors involved in diverse cellular physiology

31 March 2020

1 reference

Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress

31 March 2020

1 reference

Transcriptional induction of mammalian ER quality control proteins is mediated by single or combined action of ATF6alpha and XBP1

31 March 2020

1 reference

Activating transcription factor 4.

31 March 2020

1 reference

A CHOP-regulated microRNA controls rhodopsin expression

31 March 2020

1 reference

Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress

31 March 2020

1 reference

Mitochondria and cell death: outer membrane permeabilization and beyond

31 March 2020

1 reference

Fine-tuning of the unfolded protein response: Assembling the IRE1alpha interactome

31 March 2020

1 reference

Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1

31 March 2020

1 reference

Autophagy is activated for cell survival after endoplasmic reticulum stress

31 March 2020

1 reference

Amyotrophic lateral sclerosis pathogenesis: a journey through the secretory pathway.

31 March 2020

1 reference

Selective abrogation of BiP/GRP78 blunts activation of NF-κB through the ATF6 branch of the UPR: involvement of C/EBPβ and mTOR-dependent dephosphorylation of Akt.

31 March 2020

1 reference

Endoplasmic reticulum stress-sensing mechanisms in yeast and mammalian cells

31 March 2020

1 reference

Mammalian endoplasmic reticulum stress sensor IRE1 signals by dynamic clustering

31 March 2020

1 reference

The unfolded protein response signals through high-order assembly of Ire1

31 March 2020

1 reference

Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response

31 March 2020

1 reference

ER stress regulation of ATF6 localization by dissociation of BiP/GRP78 binding and unmasking of Golgi localization signals

31 March 2020

1 reference

In vitro reconstitution of ER-stress induced ATF6 transport in COPII vesicles

31 March 2020

1 reference

Underglycosylation of ATF6 as a novel sensing mechanism for activation of the unfolded protein response.

31 March 2020

1 reference

Role of disulfide bridges formed in the luminal domain of ATF6 in sensing endoplasmic reticulum stress

31 March 2020

1 reference

On the mechanism of sensing unfolded protein in the endoplasmic reticulum

31 March 2020

1 reference

Unfolded proteins are Ire1-activating ligands that directly induce the unfolded protein response

31 March 2020

1 reference

Activation of mammalian IRE1alpha upon ER stress depends on dissociation of BiP rather than on direct interaction with unfolded proteins.

31 March 2020

1 reference

The crystal structure of human IRE1 luminal domain reveals a conserved dimerization interface required for activation of the unfolded protein response

31 March 2020

1 reference

A time-dependent phase shift in the mammalian unfolded protein response

31 March 2020

1 reference

Intrinsic capacities of molecular sensors of the unfolded protein response to sense alternate forms of endoplasmic reticulum stress

31 March 2020

1 reference

Selective activation of the transcription factor ATF6 mediates endoplasmic reticulum proliferation triggered by a membrane protein

31 March 2020

1 reference

Dual and opposing roles of the unfolded protein response regulated by IRE1alpha and XBP1 in proinsulin processing and insulin secretion

31 March 2020

1 reference

The role of IRE1alpha in the degradation of insulin mRNA in pancreatic beta-cells

31 March 2020

1 reference

IRE1beta inhibits chylomicron production by selectively degrading MTP mRNA.

31 March 2020

1 reference

Ligand-independent dimerization activates the stress response kinases IRE1 and PERK in the lumen of the endoplasmic reticulum.

31 March 2020

1 reference

IRE1 signaling affects cell fate during the unfolded protein response

31 March 2020

1 reference

Divergent effects of PERK and IRE1 signaling on cell viability

31 March 2020

1 reference

BiP binding to the ER-stress sensor Ire1 tunes the homeostatic behavior of the unfolded protein response

31 March 2020

1 reference

Homeostatic adaptation to endoplasmic reticulum stress depends on Ire1 kinase activity

31 March 2020

1 reference

Attenuation of yeast UPR is essential for survival and is mediated by IRE1 kinase

31 March 2020

1 reference

Adaptation to ER stress is mediated by differential stabilities of pro-survival and pro-apoptotic mRNAs and proteins

31 March 2020

1 reference

Proapoptotic BAX and BAK modulate the unfolded protein response by a direct interaction with IRE1alpha

31 March 2020

1 reference

HSP72 protects cells from ER stress-induced apoptosis via enhancement of IRE1alpha-XBP1 signaling through a physical interaction

31 March 2020

1 reference

Protein-tyrosine phosphatase 1B potentiates IRE1 signaling during endoplasmic reticulum stress

31 March 2020

1 reference

AIP1 is critical in transducing IRE1-mediated endoplasmic reticulum stress response

31 March 2020

1 reference

Activation of caspase-12, an endoplastic reticulum (ER) resident caspase, through tumor necrosis factor receptor-associated factor 2-dependent mechanism in response to the ER stress

31 March 2020

1 reference

JAB1 participates in unfolded protein responses by association and dissociation with IRE1

31 March 2020

1 reference

BAX inhibitor-1 is a negative regulator of the ER stress sensor IRE1alpha

31 March 2020

1 reference

Cytoprotective gene bi-1 is required for intrinsic protection from endoplasmic reticulum stress and ischemia-reperfusion injury

31 March 2020

1 reference

Hepatic Bax inhibitor-1 inhibits IRE1alpha and protects from obesity-associated insulin resistance and glucose intolerance

31 March 2020

1 reference

Bifunctional apoptosis regulator (BAR), an endoplasmic reticulum (ER)-associated E3 ubiquitin ligase, modulates BI-1 protein stability and function in ER Stress

31 March 2020

1 reference

mTORC1 serves ER stress-triggered apoptosis via selective activation of the IRE1-JNK pathway

31 March 2020

1 reference

Flavonol Activation Defines an Unanticipated Ligand-Binding Site in the Kinase-RNase Domain of IRE1

31 March 2020

1 reference

Cofactor-mediated conformational control in the bifunctional kinase/RNase Ire1

31 March 2020

1 reference

Membrane aberrancy and unfolded proteins activate the endoplasmic reticulum stress sensor Ire1 in different ways

31 March 2020

1 reference

Peptides derived from the bifunctional kinase/RNase enzyme IRE1α modulate IRE1α activity and protect cells from endoplasmic reticulum stress.

31 March 2020

1 reference

P58IPK, a novel endoplasmic reticulum stress-inducible protein and potential negative regulator of eIF2alpha signaling

31 March 2020

1 reference

Control of PERK eIF2alpha kinase activity by the endoplasmic reticulum stress-induced molecular chaperone P58IPK.

31 March 2020

1 reference

Regulation of PERK signaling and leukemic cell survival by a novel cytosolic isoform of the UPR regulator GRP78/BiP

31 March 2020

1 reference

Calcineurin interacts with PERK and dephosphorylates calnexin to relieve ER stress in mammals and frogs

31 March 2020

1 reference

Wolfram syndrome 1 gene negatively regulates ER stress signaling in rodent and human cells

31 March 2020

1 reference

ATF6 activated by proteolysis binds in the presence of NF-Y (CBF) directly to the cis-acting element responsible for the mammalian unfolded protein response

31 March 2020

1 reference

CBF/NF-Y controls endoplasmic reticulum stress induced transcription through recruitment of both ATF6(N) and TBP.

31 March 2020

1 reference

ATF6 as a transcription activator of the endoplasmic reticulum stress element: thapsigargin stress-induced changes and synergistic interactions with NF-Y and YY1

31 March 2020

1 reference

Luminal domain of ATF6 alone is sufficient for sensing endoplasmic reticulum stress and subsequent transport to the Golgi apparatus

31 March 2020

1 reference

Cotranslational targeting of XBP1 protein to the membrane promotes cytoplasmic splicing of its own mRNA.

31 March 2020

1 reference

Translational pausing ensures membrane targeting and cytoplasmic splicing of XBP1u mRNA.

31 March 2020

1 reference

The regulatory subunits of PI3K, p85alpha and p85beta, interact with XBP-1 and increase its nuclear translocation

31 March 2020

1 reference

A regulatory subunit of phosphoinositide 3-kinase increases the nuclear accumulation of X-box-binding protein-1 to modulate the unfolded protein response

31 March 2020

1 reference

p38 MAPK-mediated regulation of Xbp1s is crucial for glucose homeostasis

31 March 2020

1 reference

Regulation of unfolded protein response modulator XBP1s by acetylation and deacetylation

31 March 2020

1 reference

SUMO modification regulates the transcriptional activity of XBP1

31 March 2020

1 reference

pXBP1(U) encoded in XBP1 pre-mRNA negatively regulates unfolded protein response activator pXBP1(S) in mammalian ER stress response

31 March 2020

1 reference

Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alpha

31 March 2020

1 reference

A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress

31 March 2020

1 reference

Selective inhibition of a regulatory subunit of protein phosphatase 1 restores proteostasis

31 March 2020

1 reference

The eIF2 kinase PERK and the integrated stress response facilitate activation of ATF6 during endoplasmic reticulum stress.

31 March 2020

1 reference

Regulation of innate immunity by signaling pathways emerging from the endoplasmic reticulum

31 March 2020

1 reference

TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages.

31 March 2020

1 reference

Adaptive suppression of the ATF4-CHOP branch of the unfolded protein response by toll-like receptor signalling

31 March 2020

1 reference

Endoplasmic reticulum stress and the inflammatory basis of metabolic disease

31 March 2020

1 reference

Regulation of insulin biosynthesis in pancreatic beta cells by an endoplasmic reticulum-resident protein kinase IRE1.

31 March 2020

1 reference

Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes

31 March 2020

1 reference

Aberrant lipid metabolism disrupts calcium homeostasis causing liver endoplasmic reticulum stress in obesity

31 March 2020

1 reference

Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1

31 March 2020

1 reference

XBP-1 is required for biogenesis of cellular secretory machinery of exocrine glands

31 March 2020

1 reference

IRE1α disruption causes histological abnormality of exocrine tissues, increase of blood glucose level, and decrease of serum immunoglobulin level

31 March 2020

1 reference

XBP1 controls maturation of gastric zymogenic cells by induction of MIST1 and expansion of the rough endoplasmic reticulum

31 March 2020

1 reference

Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival

31 March 2020

1 reference

XBP-1 regulates signal transduction, transcription factors and bone marrow colonization in B cells

31 March 2020

1 reference

The unfolded protein response sensor IRE1alpha is required at 2 distinct steps in B cell lymphopoiesis.

31 March 2020

1 reference

Surviving endoplasmic reticulum stress is coupled to altered chondrocyte differentiation and function

31 March 2020

1 reference

Regulation of hepatic lipogenesis by the transcription factor XBP1

31 March 2020

1 reference

Induction of liver steatosis and lipid droplet formation in ATF6alpha-knockout mice burdened with pharmacological endoplasmic reticulum stress

31 March 2020

1 reference

The unfolded protein response transducer IRE1α prevents ER stress-induced hepatic steatosis

31 March 2020

1 reference

ER stress controls iron metabolism through induction of hepcidin

31 March 2020

1 reference

Regulation of glucose homeostasis through a XBP-1-FoxO1 interaction

31 March 2020

1 reference

Insulin/IGF-1 signaling mutants reprogram ER stress response regulators to promote longevity

31 March 2020

1 reference

The CREB coactivator CRTC2 links hepatic ER stress and fasting gluconeogenesis

31 March 2020

1 reference

The role of brain-derived neurotrophic factor (BDNF)-induced XBP1 splicing during brain development.

31 March 2020

1 reference

Animal models in the study of the unfolded protein response.

31 March 2020

1 reference

Protein homeostasis networks in physiology and disease

31 March 2020

1 reference

Plasma cell differentiation requires the transcription factor XBP-1

31 March 2020

1 reference

Function of IRE1 alpha in the placenta is essential for placental development and embryonic viability

31 March 2020

1 reference

The unfolded protein response of B-lymphocytes: PERK-independent development of antibody-secreting cells

31 March 2020

1 reference

ATF4 is a substrate of RSK2 and an essential regulator of osteoblast biology; implication for Coffin-Lowry Syndrome

31 March 2020

1 reference

Targeted disruption of ATF4 discloses its essential role in the formation of eye lens fibres.

31 March 2020

1 reference

Protein folding stress in neurodegenerative diseases: a glimpse into the ER.

31 March 2020

1 reference

A role for motoneuron subtype-selective ER stress in disease manifestations of FALS mice

31 March 2020

1 reference

The unfolded protein response in familial amyotrophic lateral sclerosis

31 March 2020

1 reference

XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy

31 March 2020

1 reference

The proapoptotic BCL-2 family member BIM mediates motoneuron loss in a model of amyotrophic lateral sclerosis

31 March 2020

1 reference

ALS-linked mutant SOD1 induces ER stress- and ASK1-dependent motor neuron death by targeting Derlin-1.

31 March 2020

1 reference

A crucial role for RACK1 in the regulation of glucose-stimulated IRE1alpha activation in pancreatic beta cells

31 March 2020

1 reference

https://pubmed.ncbi.nlm.nih.gov/22251901

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

An essential role in liver development for transcription factor XBP-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/22251901

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=22251901

30 April 2017

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

37730

1021963057

0 references

37730

1 reference

Consolidated OpenCitations Corpus – April 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=22251901

2 references

30 April 2017

Consolidated OpenCitations Corpus – April 2017