(Q39596362)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21300844%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

title

Chronic methylglyoxal infusion by minipump causes pancreatic beta-cell dysfunction and induces type 2 diabetes in Sprague-Dawley rats (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21300844%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

0 references

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21300844%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

author name string

Arti Dhar

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21300844%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Indu Dhar

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21300844%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Bo Jiang

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21300844%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Lingyun Wu

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21300844%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

language of work or name

English

0 references

publication date

7 February 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21300844%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

number of pages

10

1 reference

inferred from page(s)

published in

Diabetes

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21300844%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

volume

60

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21300844%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21300844%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

page(s)

899-908

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21300844%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

21 January 2020

copyright license

start time

30 August 2021

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Type 2 diabetes in children and adolescents

1 reference

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GLUT2 mutations, translocation, and receptor function in diet sugar managing

25 September 2017

1 reference

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Type 2 diabetes mellitus in childhood: obesity and insulin resistance

25 September 2017

1 reference

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Methylglyoxal production in vascular smooth muscle cells from different metabolic precursors

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046851

Free radical generation by methylglyoxal in tissues

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046851

Methylglyoxal, diabetes mellitus and diabetic complications

25 September 2017

1 reference

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PDX-1 and MafA play a crucial role in pancreatic beta-cell differentiation and maintenance of mature beta-cell function

25 September 2017

1 reference

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Oxidative stress, glucose metabolism, and the prevention of type 2 diabetes: pathophysiological insights

25 September 2017

1 reference

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H2S, endoplasmic reticulum stress, and apoptosis of insulin-secreting beta cells

25 September 2017

1 reference

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CCAAT/enhancer-binding protein beta deletion reduces adiposity, hepatic steatosis, and diabetes in Lepr(db/db) mice

25 September 2017

1 reference

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Diabetes, glucose toxicity, and oxidative stress: A case of double jeopardy for the pancreatic islet beta cell

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046851

Structural and functional changes in human insulin induced by methylglyoxal

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046851

Methylglyoxal impairs the insulin signaling pathways independently of the formation of intracellular reactive oxygen species

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046851

Oxidative stress-mediated, post-translational loss of MafA protein as a contributing mechanism to loss of insulin gene expression in glucotoxic beta cells

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046851

Glycemic index, glycemic load, and risk of type 2 diabetes

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046851

ALT-711 decreases cardiovascular stiffness and has potential in diabetes, hypertension and heart failure

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046851

Glucose and tolbutamide induce apoptosis in pancreatic beta-cells. A process dependent on intracellular Ca2+ concentration

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046851

Breakers of advanced glycation end products restore large artery properties in experimental diabetes.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046851

Pathogenic effects of advanced glycosylation: biochemical, biologic, and clinical implications for diabetes and aging.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046851

The pancreatic beta-cell glucose sensor.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046851

Banting lecture 1988. Role of insulin resistance in human disease

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046851

Altered expression of muscle glucose transporter GLUT-4 in diabetic fatty Zucker rats (ZDF/Drt-fa)

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046851

Proinflammatory and proapoptotic effects of methylglyoxal on neutrophils from patients with type 2 diabetes mellitus.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046851

Accumulation of endogenous methylglyoxal impaired insulin signaling in adipose tissue of fructose-fed rats

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046851

Pancreatic islet beta-cell and oxidative stress: the importance of glutathione peroxidase

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046851

Pro-oxidant challenge in vivo provokes the onset of NIDDM in the insulin resistant obese Zucker rat.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046851

Accelerated loss of islet beta cells in sucrose-fed Goto-Kakizaki rats, a genetic model of non-insulin-dependent diabetes mellitus

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046851

Alagebrium attenuates acute methylglyoxal-induced glucose intolerance in Sprague-Dawley rats.

17 June 2018

1 reference

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Alagebrium chloride protects the heart against oxidative stress in aging rats

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046851

Methylglyoxal, protein binding and biological samples: are we getting the true measure?

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046851

Pancreatic islet overproduction of H2S and suppressed insulin release in Zucker diabetic rats

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046851

Reduced PDX-1 expression impairs islet response to insulin resistance and worsens glucose homeostasis

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046851

Defective glucose-regulated insulin gene expression associated with PDX-1 deficiency in the Psammomys obesus model of type 2 diabetes

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046851

Developmental origins of diabetes: the role of oxidative stress

21 August 2018

1 reference

12 December 2020

Methylglyoxal and advanced glycation endproducts: new therapeutic horizons?

1 reference

12 December 2020

Type 2 diabetes in youth

1 reference

12 December 2020

Monochlorobimane fluorometric method to measure tissue glutathione

1 reference

12 December 2020

Dietary patterns and risk for type 2 diabetes mellitus in U.S. men

1 reference

12 December 2020

Selective modification of glutathione metabolism

1 reference

12 December 2020

Glyoxalase System in Clinical Diabetes Mellitus and Correlation with Diabetic Complications

1 reference

12 December 2020

Role of apoptosis in failure of beta-cell mass compensation for insulin resistance and beta-cell defects in the male Zucker diabetic fatty rat

1 reference

12 December 2020

Insulin resistance in diabetes

1 reference

12 December 2020

Identifiers

DOI

10.2337/DB10-0627

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21300844%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21300844%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

1 reference