(Q39608133)

13 September 2017

title

Specifically targeting angiopoietin-2 inhibits angiogenesis, Tie2-expressing monocyte infiltration, and tumor growth (English)

1 reference

13 September 2017

Specifically Targeting Angiopoietin-2 Inhibits Angiogenesis, Tie2-Expressing Monocyte Infiltration, and Tumor Growth (English)

1 reference

https://api.crossref.org/works/10.1158/1078-0432.CCR-10-2317

22 November 2024

1 reference

Hanhua Huang

1

1 reference

13 September 2017

Jing-Yu Lai

2

1 reference

13 September 2017

Janet Do

3

1 reference

13 September 2017

Dingguo Liu

4

1 reference

13 September 2017

Lingna Li

5

1 reference

13 September 2017

Joselyn Del Rosario

6

1 reference

13 September 2017

Steven Pirie-Shepherd

8

1 reference

13 September 2017

Nancy Levin

9

1 reference

13 September 2017

Curt Bradshaw

10

1 reference

13 September 2017

Gary Woodnutt

11

1 reference

13 September 2017

Rodney Lappe

12

1 reference

13 September 2017

Abhijit Bhat

13

1 reference

13 September 2017

Venkata R. Doppalapudi

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21233403

22 November 2024

language of work or name

English

0 references

publication date

13 January 2011

1 reference

full work available at URL

13 September 2017

https://figshare.com/articles/journal_contribution/Supplementary_Data_from_Specifically_Targeting_Angiopoietin-2_Inhibits_Angiogenesis_Tie2-Expressing_Monocyte_Infiltration_and_Tumor_Growth/22444746/1/files/39895794.pdf

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21233403

http://clincancerres.aacrjournals.org/cgi/content/abstract/17/5/1001

22 November 2024

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21233403

https://aacrjournals.org/clincancerres/article-pdf/17/5/1001/2002502/1001.pdf

22 November 2024

1 reference

https://api.crossref.org/works/10.1158/1078-0432.CCR-10-2317

22 November 2024

published in

Clinical Cancer Research

1 reference

13 September 2017

volume

17

1 reference

13 September 2017

issue

5

1 reference

13 September 2017

page(s)

1001-1011

1 reference

Inhibition of angiogenesis

13 September 2017

cites work

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1 reference

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22 November 2024

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22 November 2024

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Control of vascular morphogenesis and homeostasis through the angiopoietin-Tie system

22 November 2024

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Angiopoietin-2 is required for postnatal angiogenesis and lymphatic patterning, and only the latter role is rescued by Angiopoietin-1.

22 November 2024

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Angiopoietins in malignancy

22 November 2024

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22 November 2024

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Expression and prognostic significance of angiopoietin in colorectal carcinoma

22 November 2024

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Expression of angiopoietin-1 and -2, and its clinical significance in human bladder cancer

22 November 2024

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https://api.crossref.org/works/10.1158/1078-0432.CCR-10-2317

Expression of angiopoietins and its clinical significance in non-small cell lung cancer

22 November 2024

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Angiopoietin-2 sensitizes endothelial cells to TNF-alpha and has a crucial role in the induction of inflammation

22 November 2024

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1 reference

https://api.crossref.org/works/10.1158/1078-0432.CCR-10-2317

Tie2-expressing monocytes: regulation of tumor angiogenesis and therapeutic implications

22 November 2024

13

1 reference

https://api.crossref.org/works/10.1158/1078-0432.CCR-10-2317

Angiopoietin-2 regulates gene expression in TIE2-expressing monocytes and augments their inherent proangiogenic functions.

22 November 2024

14

1 reference

https://api.crossref.org/works/10.1158/1078-0432.CCR-10-2317

Tie2 identifies a hematopoietic lineage of proangiogenic monocytes required for tumor vessel formation and a mesenchymal population of pericyte progenitors.

22 November 2024

15

1 reference

https://api.crossref.org/works/10.1158/1078-0432.CCR-10-2317

Identification of proangiogenic TIE2-expressing monocytes (TEMs) in human peripheral blood and cancer.

22 November 2024

16

1 reference

https://api.crossref.org/works/10.1158/1078-0432.CCR-10-2317

Contrasting actions of selective inhibitors of angiopoietin-1 and angiopoietin-2 on the normalization of tumor blood vessels

22 November 2024

17

1 reference

https://api.crossref.org/works/10.1158/1078-0432.CCR-10-2317

Suppression of angiogenesis and tumor growth by selective inhibition of angiopoietin-2

22 November 2024

18

1 reference

https://api.crossref.org/works/10.1158/1078-0432.CCR-10-2317

Safety, pharmacokinetics, and antitumor activity of AMG 386, a selective angiopoietin inhibitor, in adult patients with advanced solid tumors

22 November 2024

19

1 reference

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Selective activity against proliferating tumor endothelial cells by CVX-22, a thrombospondin-1 mimetic CovX-Body

22 November 2024

20

1 reference

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Chemically programmed antibodies: endothelin receptor targeting CovX-Bodies

22 November 2024

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Differential expression of angiopoietin-2 and vascular endothelial growth factor in androgen-independent prostate cancer models

22 November 2024

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Regulation of the angiopoietin-2 gene by hCG in ovarian cancer cell line OVCAR-3.

22 November 2024

23

1 reference

https://api.crossref.org/works/10.1158/1078-0432.CCR-10-2317

Angiopoietin-2 promotes disease progression of neuroendocrine tumors

22 November 2024

24

1 reference

https://api.crossref.org/works/10.1158/1078-0432.CCR-10-2317

Clinical significance of angiopoietin-2 expression at the deepest invasive tumor site of advanced colorectal carcinoma

22 November 2024

25

1 reference

https://api.crossref.org/works/10.1158/1078-0432.CCR-10-2317

Expression of the angopoietin-1, angopoietin-2, Tie2, and vascular endothelial growth factor gene in epithelial ovarian cancer

22 November 2024

26

1 reference

https://api.crossref.org/works/10.1158/1078-0432.CCR-10-2317

Angiopoietin-2 interferes with anti-VEGFR2-induced vessel normalization and survival benefit in mice bearing gliomas

22 November 2024

27

1 reference

https://api.crossref.org/works/10.1158/1078-0432.CCR-10-2317

The antiinflammatory endothelial tyrosine kinase Tie2 interacts with a novel nuclear factor-kappaB inhibitor ABIN-2.

22 November 2024

29

1 reference

https://api.crossref.org/works/10.1158/1078-0432.CCR-10-2317

ABIN-2 protects endothelial cells from death and has a role in the antiapoptotic effect of angiopoietin-1

22 November 2024

30

1 reference

https://api.crossref.org/works/10.1158/1078-0432.CCR-10-2317

Angiopoietin 2 is a partial agonist/antagonist of Tie2 signaling in the endothelium

22 November 2024

31

1 reference

https://api.crossref.org/works/10.1158/1078-0432.CCR-10-2317

A designed angiopoietin-2 variant, pentameric COMP-Ang2, strongly activates Tie2 receptor and stimulates angiogenesis

22 November 2024

32

1 reference

https://api.crossref.org/works/10.1158/1078-0432.CCR-10-2317

Angiopoietin-2 at high concentration can enhance endothelial cell survival through the phosphatidylinositol 3'-kinase/Akt signal transduction pathway

22 November 2024

33

1 reference

https://api.crossref.org/works/10.1158/1078-0432.CCR-10-2317

Angiopoietin-2 impairs revascularization after limb ischemia

22 November 2024

34

1 reference

https://api.crossref.org/works/10.1158/1078-0432.CCR-10-2317

Systemic overexpression of angiopoietin-2 promotes tumor microvessel regression and inhibits angiogenesis and tumor growth

22 November 2024

35

1 reference

https://api.crossref.org/works/10.1158/1078-0432.CCR-10-2317

Sustained angiopoietin-2 expression disrupts vessel formation and inhibits glioma growth

22 November 2024

36

1 reference

https://api.crossref.org/works/10.1158/1078-0432.CCR-10-2317

Tie2-expressing monocytes and tumor angiogenesis: regulation by hypoxia and angiopoietin-2.

22 November 2024

37

1 reference

https://api.crossref.org/works/10.1158/1078-0432.CCR-10-2317

Angiopoietin 2 expression in invasive ductal carcinoma of the breast: its relationship to the VEGF expression and microvessel density

22 November 2024

39

1 reference

https://api.crossref.org/works/10.1158/1078-0432.CCR-10-2317

Tumor-derived vascular endothelial growth factor up-regulates angiopoietin-2 in host endothelium and destabilizes host vasculature, supporting angiogenesis in ovarian cancer

22 November 2024

40

1 reference

https://api.crossref.org/works/10.1158/1078-0432.CCR-10-2317

Expression of angiopoietins and vascular endothelial growth factors and their clinical significance in acute myeloid leukemia

22 November 2024

41

1 reference

https://api.crossref.org/works/10.1158/1078-0432.CCR-10-2317

22 November 2024

Identifiers

1 reference

13 September 2017

1 reference