(Q39616452)

English

Interruption of triacylglycerol synthesis in the endoplasmic reticulum is the initiating event for saturated fatty acid-induced lipotoxicity in liver cells

scientific article published on 23 December 2010

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scholarly article

1 reference

Europe PubMed Central

13 September 2017

Interruption of triacylglycerol synthesis in the endoplasmic reticulum is the initiating event for saturated fatty acid-induced lipotoxicity in liver cells (English)

1 reference

Europe PubMed Central

13 September 2017

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endoplasmic reticulum

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author name string

Michalis D Mantzaris

1

1 reference

Europe PubMed Central

13 September 2017

Epameinondas V Tsianos

2

1 reference

Europe PubMed Central

13 September 2017

Dimitrios Galaris

3

1 reference

Europe PubMed Central

13 September 2017

language of work or name

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publication date

23 December 2010

1 reference

Europe PubMed Central

13 September 2017

1 reference

Europe PubMed Central

13 September 2017

278

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Europe PubMed Central

13 September 2017

3

1 reference

Europe PubMed Central

13 September 2017

519-530

1 reference

Europe PubMed Central

13 September 2017

Global and societal implications of the diabetes epidemic

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07972.X

21 January 2018

Molecular mechanisms of lipotoxicity in nonalcoholic fatty liver disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07972.X

21 January 2018

Lipotoxicity: when tissues overeat

1 reference

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21 January 2018

The histological course of nonalcoholic fatty liver disease: a longitudinal study of 103 patients with sequential liver biopsies

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07972.X

21 January 2018

Oleate reverses palmitate-induced insulin resistance and inflammation in skeletal muscle cells

1 reference

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21 January 2018

JNK and tumor necrosis factor-alpha mediate free fatty acid-induced insulin resistance in 3T3-L1 adipocytes

1 reference

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21 January 2018

Palmitoleate attenuates palmitate-induced Bim and PUMA up-regulation and hepatocyte lipoapoptosis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07972.X

21 January 2018

Disruption of endoplasmic reticulum structure and integrity in lipotoxic cell death

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07972.X

21 January 2018

The lysosomal-mitochondrial axis in free fatty acid-induced hepatic lipotoxicity

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07972.X

21 January 2018

Full-length adiponectin protects hepatocytes from palmitate-induced apoptosis via inhibition of c-Jun NH2 terminal kinase.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07972.X

21 January 2018

Saturated fatty acids induce endoplasmic reticulum stress and apoptosis independently of ceramide in liver cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07972.X

21 January 2018

Differential activation of ER stress and apoptosis in response to chronically elevated free fatty acids in pancreatic beta-cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07972.X

21 January 2018

Mechanisms involved in the cytotoxic and cytoprotective actions of saturated versus monounsaturated long-chain fatty acids in pancreatic beta-cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07972.X

21 January 2018

Initiation and execution of lipotoxic ER stress in pancreatic beta-cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07972.X

21 January 2018

Hepatic lipid partitioning and liver damage in nonalcoholic fatty liver disease: role of stearoyl-CoA desaturase

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07972.X

21 January 2018

Triglyceride accumulation protects against fatty acid-induced lipotoxicity

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07972.X

21 January 2018

Prolonged exposure to free fatty acids has cytostatic and pro-apoptotic effects on human pancreatic islets: evidence that beta-cell death is caspase mediated, partially dependent on ceramide pathway, and Bcl-2 regulated.

1 reference

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21 January 2018

Adverse physicochemical properties of tripalmitin in beta cells lead to morphological changes and lipotoxicity in vitro

1 reference

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21 January 2018

How do BCL-2 proteins induce mitochondrial outer membrane permeabilization?

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07972.X

21 January 2018

The BCL-2 protein family: opposing activities that mediate cell death

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07972.X

21 January 2018

Cellular and molecular mechanisms of liver injury

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07972.X

21 January 2018

Characterization of triacsin C inhibition of short-, medium-, and long-chain fatty acid: CoA ligases of human liver

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07972.X

21 January 2018

Thematic review series: glycerolipids. DGAT enzymes and triacylglycerol biosynthesis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07972.X

21 January 2018

Fatty acid transport and metabolism in HepG2 cells.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07972.X

21 January 2018

Metabolic fate of oleic acid, palmitic acid and stearic acid in cultured hamster hepatocytes

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07972.X

21 January 2018

Effects of diacylglycerols and Ca2+ on structure of phosphatidylcholine/phosphatidylserine bilayers

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07972.X

21 January 2018

Specificity of the fatty acyl moieties of diacylglycerol for the activation of calcium-activated, phospholipid-dependent protein kinase.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07972.X

21 January 2018

Effects of dipalmitoylglycerol and fatty acids on membrane structure and protein kinase C activity

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07972.X

21 January 2018

Differential regulation of the endoplasmic reticulum stress response in pancreatic beta-cells exposed to long-chain saturated and monounsaturated fatty acids

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07972.X

21 January 2018

Signal integration in the endoplasmic reticulum unfolded protein response

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07972.X

21 January 2018

From endoplasmic-reticulum stress to the inflammatory response

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07972.X

21 January 2018

ER stress and diseases.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07972.X

21 January 2018

Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07972.X

21 January 2018

Activation and dysregulation of the unfolded protein response in nonalcoholic fatty liver disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07972.X

21 January 2018

Chronic palmitate but not oleate exposure induces endoplasmic reticulum stress, which may contribute to INS-1 pancreatic beta-cell apoptosis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07972.X

21 January 2018

Group IVA phospholipase A2 is necessary for the biogenesis of lipid droplets.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07972.X

21 January 2018

Features of apoptotic cells measured by flow cytometry

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07972.X

21 January 2018

A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07972.X

21 January 2018

Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07972.X

21 January 2018

Identifiers

10.1111/J.1742-4658.2010.07972.X

1 reference

Europe PubMed Central

13 September 2017

release_kuzrbunvxrcw3d27usrz7k6gli

1 reference

https://api.fatcat.wiki/v0/release/kuzrbunvxrcw3d27usrz7k6gli

24 November 2022

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Europe PubMed Central

13 September 2017

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