(Q39627572)

English

Itch/AIP4-independent proteasomal degradation of cFLIP induced by the histone deacetylase inhibitor SAHA sensitizes breast tumour cells to TRAIL.

scientific article published on 25 November 2010

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scholarly article

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Europe PubMed Central

PubMed publication ID

13 September 2017

Itch/AIP4-independent proteasomal degradation of cFLIP induced by the histone deacetylase inhibitor SAHA sensitizes breast tumour cells to TRAIL. (English)

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

Abelardo López-Rivas

2

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

language of work or name

1 reference

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publication date

25 November 2010

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

Investigational New Drugs

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

30

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

2

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

541-547

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

Safety and antitumor activity of recombinant soluble Apo2 ligand

1 reference

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21 January 2018

Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo.

1 reference

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21 January 2018

Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5.

1 reference

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21 January 2018

FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2

1 reference

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21 January 2018

Directing cancer cells to self-destruct with pro-apoptotic receptor agonists

1 reference

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21 January 2018

Inhibition of death receptor-mediated gene induction by a cycloheximide-sensitive factor occurs at the level of or upstream of Fas-associated death domain protein (FADD)

1 reference

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21 January 2018

Inhibition of death receptor signals by cellular FLIP

1 reference

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21 January 2018

New insights into apoptosis signaling by Apo2L/TRAIL.

1 reference

https://api.crossref.org/works/10.1007%2FS10637-010-9597-X

21 January 2018

NF-kappaB inducers upregulate cFLIP, a cycloheximide-sensitive inhibitor of death receptor signaling

1 reference

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21 January 2018

Accelerated degradation of cellular FLIP protein through the ubiquitin-proteasome pathway in p53-mediated apoptosis of human cancer cells

1 reference

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21 January 2018

The E3 ubiquitin ligase itch couples JNK activation to TNFalpha-induced cell death by inducing c-FLIP(L) turnover

1 reference

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21 January 2018

Cisplatin induces p53-dependent FLICE-like inhibitory protein ubiquitination in ovarian cancer cells.

1 reference

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21 January 2018

Flavopiridol induces cellular FLICE-inhibitory protein degradation by the proteasome and promotes TRAIL-induced early signaling and apoptosis in breast tumor cells

1 reference

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21 January 2018

The histone deacetylase inhibitor suberoylanilide hydroxamic acid sensitises human hepatocellular carcinoma cells to TRAIL-induced apoptosis by TRAIL-DISC activation.

1 reference

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21 January 2018

Combination therapy of established cancer using a histone deacetylase inhibitor and a TRAIL receptor agonist

1 reference

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21 January 2018

Histone deacetylase inhibitors interact synergistically with tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) to induce apoptosis in carcinoma cell lines

1 reference

https://api.crossref.org/works/10.1007%2FS10637-010-9597-X

21 January 2018

The histone deacetylase inhibitor suberic bishydroxamate: a potential sensitizer of melanoma to TNF-related apoptosis-inducing ligand (TRAIL) induced apoptosis.

1 reference

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21 January 2018

Modulation of tumor necrosis factor apoptosis-inducing ligand- induced NF-kappa B activation by inhibition of apical caspases

1 reference

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21 January 2018

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

1 reference

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21 January 2018

Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis

1 reference

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21 January 2018

Bim upregulation by histone deacetylase inhibitors mediates interactions with the Bcl-2 antagonist ABT-737: evidence for distinct roles for Bcl-2, Bcl-xL, and Mcl-1.

1 reference

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21 January 2018

Interactive effects of HDAC inhibitors and TRAIL on apoptosis are associated with changes in mitochondrial functions and expressions of cell cycle regulatory genes in multiple myeloma

1 reference

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21 January 2018

TRAIL-R deficiency in mice enhances lymph node metastasis without affecting primary tumor development

1 reference

https://api.crossref.org/works/10.1007%2FS10637-010-9597-X

21 January 2018

The TRAIL apoptotic pathway in cancer onset, progression and therapy

1 reference

https://api.crossref.org/works/10.1007%2FS10637-010-9597-X

21 January 2018

IL-4 protects tumor cells from anti-CD95 and chemotherapeutic agents via up-regulation of antiapoptotic proteins

1 reference

https://api.crossref.org/works/10.1007%2FS10637-010-9597-X

21 January 2018

Regulation of apoptosis proteins in cancer cells by ubiquitin

1 reference

https://api.crossref.org/works/10.1007%2FS10637-010-9597-X

21 January 2018

Histone deacetylase inhibitors: mechanisms and clinical significance in cancer: HDAC inhibitor-induced apoptosis

1 reference

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21 January 2018

Anticancer activities of histone deacetylase inhibitors

1 reference

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21 January 2018

Rational combinations using HDAC inhibitors

1 reference

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21 January 2018

The many roles of histone deacetylases in development and physiology: implications for disease and therapy

1 reference

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21 January 2018

Histone acetylation-independent effect of histone deacetylase inhibitors on Akt through the reshuffling of protein phosphatase 1 complexes

1 reference

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21 January 2018

HDAC-6 interacts with and deacetylates tubulin and microtubules in vivo

1 reference

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21 January 2018

Activation-induced degradation of FLIP(L) is mediated via the phosphatidylinositol 3-kinase/Akt signaling pathway in macrophages

1 reference

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21 January 2018

A TNF- and c-Cbl-dependent FLIP(S)-degradation pathway and its function in Mycobacterium tuberculosis-induced macrophage apoptosis

1 reference

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21 January 2018

Regulatory cross-talk between lysine acetylation and ubiquitination: role in the control of protein stability

1 reference

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21 January 2018

Bim plays a crucial role in synergistic induction of apoptosis by the histone deacetylase inhibitor SBHA and TRAIL in melanoma cells

1 reference

https://api.crossref.org/works/10.1007%2FS10637-010-9597-X

21 January 2018

Chemotherapy augments TRAIL-induced apoptosis in breast cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/21107885

12 December 2020

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10.1007/S10637-010-9597-X

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

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