(Q39633191)

English

1-Cyclohexyl-4-(4-arylcyclohexyl)piperazines: Mixed σ and human Δ(8)-Δ(7) sterol isomerase ligands with antiproliferative and P-glycoprotein inhibitory activity

scientific article published on January 2011

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Europe PubMed Central

PubMed publication ID

13 September 2017

1-Cyclohexyl-4-(4-arylcyclohexyl)piperazines: Mixed σ and human Δ(8)-Δ(7) sterol isomerase ligands with antiproliferative and P-glycoprotein inhibitory activity (English)

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

1

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Europe PubMed Central

PubMed publication ID

13 September 2017

2

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Europe PubMed Central

PubMed publication ID

13 September 2017

Marialessandra Contino

3

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Europe PubMed Central

PubMed publication ID

13 September 2017

Roberto Perrone

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Roberto Perrone

6

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author name string

Nicola Antonio Colabufo

4

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

Savina Ferorelli

5

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Europe PubMed Central

PubMed publication ID

13 September 2017

Francesco Berardi

7

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Europe PubMed Central

PubMed publication ID

13 September 2017

publication date

1 January 2011

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Europe PubMed Central

PubMed publication ID

13 September 2017

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

6

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Europe PubMed Central

PubMed publication ID

13 September 2017

1

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Europe PubMed Central

PubMed publication ID

13 September 2017

73-80

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Europe PubMed Central

PubMed publication ID

13 September 2017

Tyrosine kinase - Role and significance in Cancer.

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Inhibitors of multidrug resistance to antitumor agents (MDR).

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Imaging of sigma1 receptors in the human brain using PET and [11C]SA4503.

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Antiproliferative and cytotoxic effects of some sigma2 agonists and sigma1 antagonists in tumour cell lines

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A structure-affinity and comparative molecular field analysis of sigma-2 (sigma2) receptor ligands

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4-(tetralin-1-yl)- and 4-(naphthalen-1-yl)alkyl derivatives of 1-cyclohexylpiperazine as sigma receptor ligands with agonist sigma2 activity

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Cyclohexylpiperazine derivative PB28, a sigma2 agonist and sigma1 antagonist receptor, inhibits cell growth, modulates P-glycoprotein, and synergizes with anthracyclines in breast cancer.

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Is the sigma2 receptor a histone binding protein?

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Interaction of the sigma(2) receptor ligand PB28 with the human nucleosome: computational and experimental probes of interaction with the H2A/H2B dimer

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Subcellular Localization of Sigma-2 Receptors in Breast Cancer Cells Using Two-Photon and Confocal Microscopy

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Small molecule antagonists of the sigma-1 receptor cause selective release of the death program in tumor and self-reliant cells and inhibit tumor growth in vitro and in vivo

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Selective sigma-2 ligands preferentially bind to pancreatic adenocarcinomas: applications in diagnostic imaging and therapy

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Sigma-2 receptor ligands potentiate conventional chemotherapies and improve survival in models of pancreatic adenocarcinoma

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Screening of anti-glioma effects induced by sigma-1 receptor ligands: potential new use for old anti-psychiatric medicines

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The mysteries of sigma receptors: new family members reveal a role in cholesterol synthesis

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SR31747A is a sigma receptor ligand exhibiting antitumoural activity both in vitro and in vivo

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SR31747A: a peripheral sigma ligand with potent antitumor activities

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New sigma and 5-HT1A receptor ligands: omega-(tetralin-1-yl)-n-alkylamine derivatives

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7 January 2021

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Novel 4-(4-aryl)cyclohexyl-1-(2-pyridyl)piperazines as Delta(8)-Delta(7) sterol isomerase (emopamil binding protein) selective ligands with antiproliferative activity

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Small P-gp modulating molecules: SAR studies on tetrahydroisoquinoline derivatives

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4-Biphenyl and 2-naphthyl substituted 6,7-dimethoxytetrahydroisoquinoline derivatives as potent P-gp modulators

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Conversion of a highly selective sigma-1 receptor-ligand to sigma-2 receptor preferring ligands with anticocaine activity

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A novel substituted piperazine, CM156, attenuates the stimulant and toxic effects of cocaine in mice

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Identifiers

10.1002/CMDC.201000371

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

ResearchGate publication ID

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