(Q39636362)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21046426%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

title

Putative mechanisms of antitumor activity of cyano-substituted heteroaryles in HeLa cells (English)

1 reference

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15 January 2020

2

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15 January 2020

Marko Marjanović

4

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15 January 2020

David Lembo

5

1 reference

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15 January 2020

Ivana Jarak

8

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15 January 2020

10

Marijeta Kralj

1 reference

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15 January 2020

author name string

Katja Ester

1

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15 January 2020

Kristina Majsec

3

1 reference

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15 January 2020

Manuela Donalisio

6

1 reference

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15 January 2020

Tomislav Šmuc

7

1 reference

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15 January 2020

Grace Karminski-Zamola

9

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15 January 2020

publication date

3 November 2010

1 reference

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Investigational New Drugs

15 January 2020

published in

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15 January 2020

volume

30

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15 January 2020

issue

2

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15 January 2020

page(s)

450-467

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https://scigraph.springernature.com/pub.10.1007/s10637-010-9571-7

15 January 2020

exact match

0 references

cites work

Novel cyano- and amidinobenzothiazole derivatives: synthesis, antitumor evaluation, and X-ray and quantitative structure-activity relationship (QSAR) analysis.

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Novel amidino-substituted thienyl- and furylvinylbenzimidazole: derivatives and their photochemical conversion into corresponding diazacyclopenta[c]fluorenes. synthesis, interactions with DNA and RNA, and antitumor evaluation. 4.

21 January 2018

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Discovery of 1-benzoyl-3-cyanopyrrolo[1,2-a]quinolines as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 2: Structure-activity relationships of the 4-, 5-, 6-, 7- and 8-positions

21 January 2018

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Novel derivatives of pyridylbenzo[b]thiophene-2-carboxamides and benzo[b]thieno[2,3-c]naphthyridin-2-ones: minor structural variations provoke major differences of antitumor action mechanisms

21 January 2018

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Novel cyano- and N-isopropylamidino-substituted derivatives of benzo[b]thiophene-2-carboxanilides and benzo[b]thieno[2,3-c]quinolones: synthesis, photochemical synthesis, crystal structure determination, and antitumor evaluation. 2.

21 January 2018

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Novel cyano- and amidino-substituted derivatives of thieno[2,3-b]- and thieno[3,2-b]thiophene-2-carboxanilides and thieno[3',2':4,5]thieno- and thieno[2',3':4,5]thieno [2,3-c]quinolones: synthesis, photochemical synthesis, DNA binding, and antitumor

21 January 2018

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Synthesis, photochemical synthesis, DNA binding and antitumor evaluation of novel cyano- and amidino-substituted derivatives of naphtho-furans, naphtho-thiophenes, thieno-benzofurans, benzo-dithiophenes and their acyclic precursors

21 January 2018

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Laetrile for cancer: a systematic review of the clinical evidence

21 January 2018

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Amygdalin induces apoptosis through regulation of Bax and Bcl-2 expressions in human DU145 and LNCaP prostate cancer cells

21 January 2018

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Discovery of 1-benzoyl-3-cyanopyrrolo[1,2-a]quinolines as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. Part 1: Structure-activity relationships of the 1- and 3-positions

21 January 2018

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Discovery of 4-aryl-4H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based HTS assay. Part 5: modifications of the 2- and 3-positions

21 January 2018

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Synthesis, X-ray crystal structures, stabilities, and in vitro cytotoxic activities of new heteroarylacrylonitriles

21 January 2018

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Structure-activity relationships of novel heteroaryl-acrylonitriles as cytotoxic and antibacterial agents.

21 January 2018

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Benzimidazole derivatives related to 2,3-acrylonitriles, benzimidazo[1,2-a]quinolines and fluorenes: synthesis, antitumor evaluation in vitro and crystal structure determination

21 January 2018

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Atypical cytostatic mechanism of N-1-sulfonylcytosine derivatives determined by in vitro screening and computational analysis.

21 January 2018

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Identifying Important Risk Factors for Survival in Kidney Graft Failure Patients Using Random Survival Forests

21 January 2018

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Gene selection and classification of microarray data using random forest.

21 January 2018

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Conditional variable importance for random forests

21 January 2018

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Forensic genetics and ethical, legal and social implications beyond the clinic

21 January 2018

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The use of total protein stains as loading controls: an alternative to high-abundance single-protein controls in semi-quantitative immunoblotting

21 January 2018

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A microplate assay for the detection of oxidative products using 2',7'-dichlorofluorescin-diacetate

21 January 2018

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Persistent use of "false" cell lines

21 January 2018

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Endogenous human papillomavirus E6 and E7 proteins differentially regulate proliferation, senescence, and apoptosis in HeLa cervical carcinoma cells

21 January 2018

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DNA damage-dependent cyclin D1 proteolysis: GSK3beta holds the smoking gun

21 January 2018

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Temsirolimus downregulates p21 without altering cyclin D1 expression and induces autophagy and synergizes with vorinostat in mantle cell lymphoma

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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The cytoskeleton and cancer

21 January 2018

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Mesenchyme Forkhead 1 (FOXC2) plays a key role in metastasis and is associated with aggressive basal-like breast cancers

21 January 2018

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The role of epithelial-mesenchymal transition in cancer pathology

21 January 2018

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Control of tumourigenesis by the Scribble/Dlg/Lgl polarity module

21 January 2018

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Human papillomaviruses, cervical cancer and cell polarity

21 January 2018

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Reactive oxygen species, cellular redox systems, and apoptosis

21 January 2018

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Compound C sensitizes Caki renal cancer cells to TRAIL-induced apoptosis through reactive oxygen species-mediated down-regulation of c-FLIPL and Mcl-1.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Interaction of cyanide and nitric oxide with cytochrome c oxidase: implications for acute cyanide toxicity

21 January 2018

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Redox state of cytochrome c regulates cellular ROS and caspase cascade in permeablized cell model

21 January 2018

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21 January 2018

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21 January 2018

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12 December 2020

Caspase 3-mediated cleavage of p21WAF1/CIP1 associated with the cyclin A-cyclin-dependent kinase 2 complex is a prerequisite for apoptosis in SK-HEP-1 cells

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12 December 2020

Transformed and tumor-derived human cells exhibit preferential sensitivity to the thiol antioxidants, N-acetyl cysteine and penicillamine.

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12 December 2020

Taxol, cytochalasin B and colchicine effects on fibroblast migration and contraction: a role in glaucoma filtration surgery?

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12 December 2020

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12 December 2020