(Q37333588)

19 August 2017

1 reference

title

Control of tumourigenesis by the Scribble/Dlg/Lgl polarity module (English)

1 reference

19 August 2017

I Elsum

5

0 references

Helena E. Richardson

object named as

H E Richardson

6

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author name string

P O Humbert

1

1 reference

19 August 2017

N A Grzeschik

2

1 reference

19 August 2017

A M Brumby

3

1 reference

19 August 2017

R Galea

4

1 reference

19 August 2017

language of work or name

English

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publication date

1 November 2008

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19 August 2017

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19 August 2017

27

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19 August 2017

6888-6907

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19 August 2017

55

1 reference

https://scigraph.springernature.com/pub.10.1038/onc.2008.341

19 August 2017

0 references

cites work

Mechanisms for removal of developmentally abnormal cells: cell competition and morphogenetic apoptosis

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https://api.crossref.org/works/10.1038%2FONC.2008.341

The transcription factor ZEB1 (deltaEF1) promotes tumour cell dedifferentiation by repressing master regulators of epithelial polarity

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2008.341

Scribble protein domain mapping reveals a multistep localization mechanism and domains necessary for establishing cortical polarity

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2008.341

Dlg, Scrib and Lgl regulate neuroblast cell size and mitotic spindle asymmetry

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2008.341

Cell signalling: MAGUK magic

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

The PDZ domain-binding motif of the human T cell leukemia virus type 1 tax protein induces mislocalization of the tumor suppressor hScrib in T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Polarity complex proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Mammalian Scribble forms a tight complex with the betaPIX exchange factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Drosophila nonmuscle myosin II promotes the asymmetric segregation of cell fate determinants by cortical exclusion rather than active transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Drosophila brain tumor metastases express both neuronal and glial cell type markers

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2008.341

Metastatic ability of Drosophila tumors depends on MMP activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Phosphorylation-induced autoinhibition regulates the cytoskeletal protein Lethal (2) giant larvae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

The Par complex directs asymmetric cell division by phosphorylating the cytoskeletal protein Lgl.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Asymmetric segregation of the tumor suppressor brat regulates self-renewal in Drosophila neural stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

p32 is a novel mammalian Lgl binding protein that enhances the activity of protein kinase Czeta and regulates cell polarity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Cooperative regulation of cell polarity and growth by Drosophila tumor suppressors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Localization of apical epithelial determinants by the basolateral PDZ protein Scribble

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Integrated activity of PDZ protein complexes regulates epithelial polarity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Epithelial polarity and proliferation control: links from the Drosophila neoplastic tumor suppressors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

The Drosophila homolog of the Exo84 exocyst subunit promotes apical epithelial identity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Identification of Drosophila type II neuroblast lineages containing transit amplifying ganglion mother cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Zonula adherens formation in Caenorhabditis elegans requires dlg-1, the homologue of the Drosophila gene discs large.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

The tumor suppressors Brat and Numb regulate transit-amplifying neuroblast lineages in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

A genetic screen for dominant modifiers of a cyclin E hypomorphic mutation identifies novel regulators of S-phase entry in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

scribble mutants cooperate with oncogenic Ras or Notch to cause neoplastic overgrowth in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Using Drosophila melanogaster to map human cancer pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

LAP proteins: what's up with epithelia?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

A kinase-regulated PDZ-domain interaction controls endocytic sorting of the beta2-adrenergic receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Craniofacial dysmorphogenesis including cleft palate in mice with an insertional mutation in the discs large gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Induction of tumor growth by altered stem-cell asymmetric division in Drosophila melanogaster.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Differential expression of the human homologue of drosophila discs large oncosuppressor in histologic samples from human papillomavirus-associated lesions as a marker for progression to malignancy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Dap160/intersectin binds and activates aPKC to regulate cell polarity and cell cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Developmental signaling pathways in brain tumor-derived stem-like cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Wnt/beta-catenin signaling in development and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Drosophila myc regulates organ size by inducing cell competition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Regulation of Lethal giant larvae by Dishevelled

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

hScrib is a functional homologue of the Drosophila tumour suppressor Scribble

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

The tumour-suppressor Scribble dictates cell polarity during directed epithelial migration: regulation of Rho GTPase recruitment to the leading edge

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Atypical PKCiota contributes to poor prognosis through loss of apical-basal polarity and cyclin E overexpression in ovarian cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Cdc42 and Par6-PKCzeta regulate the spatially localized association of Dlg1 and APC to control cell polarization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

PAK1 and aPKCzeta regulate myosin II-B phosphorylation: a novel signaling pathway regulating filament assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Distinct mechanisms of apoptosis-induced compensatory proliferation in proliferating and differentiating tissues in the Drosophila eye.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

The timing of drosophila salivary gland apoptosis displays an l(2)gl-dose response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Mammary stem cells and breast cancer--role of Notch signalling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Identification of MAGI-3 as a transforming growth factor-alpha tail binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Oncogenic function for the Dlg1 mammalian homolog of the Drosophila discs-large tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Selective PDZ protein-dependent stimulation of phosphatidylinositol 3-kinase by the adenovirus E4-ORF1 oncoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Somatic mutations and altered expression of the candidate tumor suppressors CSNK1 epsilon, DLG1, and EDD/hHYD in mammary ductal carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Membrane-associated guanylate kinases regulate adhesion and plasticity at cell junctions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Myc, cell competition, and compensatory proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Structurally conserved interaction of Lgl family with SNAREs is critical to their cellular function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

The nuclear RhoA exchange factor Net1 interacts with proteins of the Dlg family, affects their localization, and influences their tumor suppressor activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Human discs large and scrib are localized at the same regions in colon mucosa and changes in their expression patterns are correlated with loss of tissue architecture during malignant progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Developmental capacities of benign and malignant neoplasms ofDrosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Malignant Neoplasms of Genetic Origin in Drosophila melanogaster

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Tumor suppressors: control of signaling by endocytosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Spindle orientation, asymmetric division and tumour suppression in Drosophila stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Novel spatiotemporal patterns of epithelial tumor invasion in Drosophila discs large egg chambers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

SCALLOPED interacts with YORKIE, the nuclear effector of the hippo tumor-suppressor pathway in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

aPKCzeta cortical loading is associated with Lgl cytoplasmic release and tumor growth in Drosophila and human epithelia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

The human protein Hugl-1 substitutes for Drosophila lethal giant larvae tumour suppressor function in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Abnormalities in cell proliferation and apico-basal cell polarity are separable in Drosophila lgl mutant clones in the developing eye.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

21 January 2018

The Hallmarks of Cancer

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Adherens junction-dependent and -independent steps in the establishment of epithelial cell polarity in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

The Salvador-Warts-Hippo pathway - an emerging tumour-suppressor network

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Direct interaction of Frizzled-1, -2, -4, and -7 with PDZ domains of PSD-95

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

PDZ domain-binding motif of human T-cell leukemia virus type 1 Tax oncoprotein augments the transforming activity in a rat fibroblast cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Organizing a functional junctional complex requires specific domains of the Drosophila MAGUK Discs large

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Compensatory proliferation induced by cell death in the Drosophila wing disc requires activity of the apical cell death caspase Dronc in a nonapoptotic role

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

The Scribble and Par complexes in polarity and migration: friends or foes?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Sequential roles of Cdc42, Par-6, aPKC, and Lgl in the establishment of epithelial polarity during Drosophila embryogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Loss of cell polarity drives tumor growth and invasion through JNK activation in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Abnormal development of urogenital organs in Dlgh1-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

The APC-hDLG complex negatively regulates cell cycle progression from the G0/G1 to S phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Modeling migration and metastasis in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Scribble associates with two polarity proteins, Lgl2 and Vangl2, via distinct molecular domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Human scribble accumulates in colorectal neoplasia in association with an altered distribution of beta-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Role of the polarity determinant crumbs in suppressing mammalian epithelial tumor progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Binding of high-risk human papillomavirus E6 oncoproteins to the human homologue of the Drosophila discs large tumor suppressor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Planar cell polarization: an emerging model points in the right direction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Loss of cell polarity causes severe brain dysplasia in Lgl1 knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Cooperative regulation of AJM-1 controls junctional integrity in Caenorhabditis elegans epithelia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Genetically distinct and clinically relevant subtypes of glioblastoma defined by array-based comparative genomic hybridization (array-CGH).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Expression of Dickkopf genes is strongly reduced in malignant melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Thyrotropin receptor trafficking relies on the hScrib-betaPIX-GIT1-ARF6 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Lethal giant larvae controls the localization of notch-signaling regulators numb, neuralized, and Sanpodo in Drosophila sensory-organ precursor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Human homolog of disc-large is required for adherens junction assembly and differentiation of human intestinal epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Lgl, Pins and aPKC regulate neuroblast self-renewal versus differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Binding of human virus oncoproteins to hDlg/SAP97, a mammalian homolog of the Drosophila discs large tumor suppressor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

LET-413 is a basolateral protein required for the assembly of adherens junctions in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Basolateral targeting by leucine-rich repeat domains in epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Differential expression of human Dlg in cervical intraepithelial neoplasias

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Endocytic control of epithelial polarity and proliferation in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Discs-large homolog 1 regulates smooth muscle orientation in the mouse ureter

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

The human papillomavirus E6 protein and its contribution to malignant progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Phosphorylation of the discs large tumour suppressor protein controls its membrane localisation and enhances its susceptibility to HPV E6-induced degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Recruitment of scribble to the synaptic scaffolding complex requires GUK-holder, a novel DLG binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Binding of APC to the human homolog of the Drosophila discs large tumor suppressor protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

A mosaic genetic screen for Drosophila neoplastic tumor suppressor genes based on defective pupation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Identification of Vangl2 and Scrb1 as planar polarity genes in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Asymmetric localization of Vangl2 and Fz3 indicate novel mechanisms for planar cell polarity in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

dMyc transforms cells into super-competitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Biological activities and molecular targets of the human papillomavirus E7 oncoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Disruption of scribble (Scrb1) causes severe neural tube defects in the circletail mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Mammalian homolog of Drosophila tumor suppressor lethal (2) giant larvae interacts with basolateral exocytic machinery in Madin-Darby canine kidney cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Human homolog of Drosophila tumor suppressor Scribble negatively regulates cell-cycle progression from G1 to S phase by localizing at the basolateral membrane in epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Human scribble (Vartul) is targeted for ubiquitin-mediated degradation by the high-risk papillomavirus E6 proteins and the E6AP ubiquitin-protein ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Junctional recruitment of mammalian Scribble relies on E-cadherin engagement

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

High resolution genomic analysis of sporadic breast cancer using array-based comparative genomic hybridization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Failure of epithelial tube maintenance causes hydrocephalus and renal cysts in Dlg5-/- mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

The PDZ ligand domain of the human papillomavirus type 16 E6 protein is required for E6's induction of epithelial hyperplasia in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Requirement of PDZ-containing proteins for cell cycle regulation and differentiation in the mouse lens epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Epithelial coating controls mesenchymal shape change through tissue-positioning effects and reduction of surface-minimizing tension.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Role of cortical tumour-suppressor proteins in asymmetric division of Drosophila neuroblast

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Scrib controls Cdc42 localization and activity to promote cell polarization during astrocyte migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Transforming properties of YAP, a candidate oncogene on the chromosome 11q22 amplicon

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

A Genetic Screen in Drosophila for Metastatic Behavior

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

The tumour-suppressor genes lgl and dlg regulate basal protein targeting in Drosophila neuroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Caspase inhibition during apoptosis causes abnormal signalling and developmental aberrations in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

A polarity complex of mPar-6 and atypical PKC binds, phosphorylates and regulates mammalian Lgl.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

The mammalian Scribble polarity protein regulates epithelial cell adhesion and migration through E-cadherin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Tumors are unique organs defined by abnormal signaling and context

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Atypical protein kinase C iota is an oncogene in human non-small cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Regulation of membrane localization of Sanpodo by lethal giant larvae and neuralized in asymmetrically dividing cells of Drosophila sensory organs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

The Crumbs3-Pals1 complex participates in the establishment of polarity in mammalian epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Drosophila aPKC regulates cell polarity and cell proliferation in neuroblasts and epithelia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Protein kinase Cgamma regulates myosin IIB phosphorylation, cellular localization, and filament assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

The multifaceted role of Notch in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Apoptotic cells can induce compensatory cell proliferation through the JNK and the Wingless signaling pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

mPins modulates PSD-95 and SAP102 trafficking and influences NMDA receptor surface expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Reduced expression of Hugl-1, the human homologue of Drosophila tumour suppressor gene lgl, contributes to progression of colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Zebrafish penner/lethal giant larvae 2 functions in hemidesmosome formation, maintenance of cellular morphology and growth regulation in the developing basal epidermis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

DaPKC-dependent phosphorylation of Crumbs is required for epithelial cell polarity in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

DLGH1 is a negative regulator of T-lymphocyte proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

The Drosophila lethal(2)giant larvae tumor suppressor protein forms homo-oligomers and is associated with nonmuscle myosin II heavy chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Protein kinase C phosphorylates nonmuscle myosin-II heavy chain from Drosophila but regulation of myosin function by this enzyme is not required for viability in flies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Tax oncoprotein of HTLV-1 binds to the human homologue of Drosophila discs large tumor suppressor protein, hDLG, and perturbs its function in cell growth control

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Basolateral junctions are sufficient to suppress epithelial invasion during Drosophila oogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Human scribble, a novel tumor suppressor identified as a target of high-risk HPV E6 for ubiquitin-mediated degradation, interacts with adenomatous polyposis coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Interactions between the crumbs, lethal giant larvae and bazooka pathways in epithelial polarization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Changes in gene expression during progression of ovarian carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Molecular evolution of the MAGUK family in metazoan genomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Epithelial cell polarity and cell junctions in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Epithelial-mesenchymal transitions in tumour progression

21 January 2018

1 reference

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The hScrib/Dlg apico-basal control complex is differentially targeted by HPV-16 and HPV-18 E6 proteins

21 January 2018

1 reference

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JNK- and Fos-regulated Mmp1 expression cooperates with Ras to induce invasive tumors in Drosophila

21 January 2018

1 reference

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Non-cell-autonomous induction of tissue overgrowth by JNK/Ras cooperation in a Drosophila tumor model

21 January 2018

1 reference

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Endosomal entry regulates Notch receptor activation in Drosophila melanogaster

21 January 2018

1 reference

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Binding of PTEN to specific PDZ domains contributes to PTEN protein stability and phosphorylation by microtubule-associated serine/threonine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Segregation of receptor and ligand regulates activation of epithelial growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Lpp is involved in Wnt/PCP signaling and acts together with Scrib to mediate convergence and extension movements during zebrafish gastrulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Drosophila models for cancer research.

21 January 2018

1 reference

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Dual roles of zygotic and maternal Scribble1 in neural migration and convergent extension movements in zebrafish embryos.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Aurora-A acts as a tumor suppressor and regulates self-renewal of Drosophila neuroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Changes in expression of the human homologue of the Drosophila discs large tumour suppressor protein in high-grade premalignant cervical neoplasias

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Trafficking of NMDA receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

The transcription factor snail represses Crumbs3 expression and disrupts apico-basal polarity complexes

21 January 2018

1 reference

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Lethal giant larvae take on a life of their own.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Cell polarity in development and cancer.

21 January 2018

1 reference

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Tumor suppressors: linking cell polarity and growth control.

21 January 2018

1 reference

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Phosphatidylinositol-3-kinase-atypical protein kinase C signaling is required for Wnt attraction and anterior-posterior axon guidance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Growth, metastasis, and invasiveness of Drosophila tumors caused by mutations in specific tumor suppressor genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Molecular cloning of the lethal(1)discs large-1 oncogene of Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Dlg protein is required for junction structure, cell polarity, and proliferation control in Drosophila epithelia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Cerebellar long-term depression requires PKC-regulated interactions between GluR2/3 and PDZ domain-containing proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Direct binding of the human homologue of the Drosophila disc large tumor suppressor gene to seven-pass transmembrane proteins, tumor endothelial marker 5 (TEM5), and a novel TEM5-like protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Lgl mediates apical domain disassembly by suppressing the PAR-3-aPKC-PAR-6 complex to orient apical membrane polarity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Mammalian Lgl Forms a Protein Complex with PAR-6 and aPKC Independently of PAR-3 to Regulate Epithelial Cell Polarity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Role of Lgl/Dlg/Scribble in the regulation of epithelial junction, polarity and growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis

21 January 2018

1 reference

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Direct binding of Lgl2 to LGN during mitosis and its requirement for normal cell division

21 January 2018

1 reference

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Cell polarity: Versatile scaffolds keep things in place.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

A focused and efficient genetic screening strategy in the mouse: identification of mutations that disrupt cortical development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Domains controlling cell polarity and proliferation in the Drosophila tumor suppressor Scribble

21 January 2018

1 reference

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The emerging role of the hippo pathway in cell contact inhibition, organ size control, and cancer development in mammals

21 January 2018

1 reference

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Lethal giant larvae proteins interact with the exocyst complex and are involved in polarized exocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Dishevelled promotes axon differentiation by regulating atypical protein kinase C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Basolateral junctions utilize warts signaling to control epithelial-mesenchymal transition and proliferation crucial for migration and invasion of Drosophila ovarian epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

The overexpression and altered localization of the atypical protein kinase C λ/ι in breast cancer correlates with the pathologic type of these tumors

21 January 2018

1 reference

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Par complex in cancer: a regulator of normal cell polarity joins the dark side

21 January 2018

1 reference

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Loss of human Scribble cooperates with H-Ras to promote cell invasion through deregulation of MAPK signalling

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Polarity regulators and the control of epithelial architecture, cell migration, and tumorigenesis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Polarity proteins in migration and invasion

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

NE-dlg, a mammalian homolog of Drosophila dlg tumor suppressor, induces growth suppression and impairment of cell adhesion: possible involvement of down-regulation of beta-catenin by NE-dlg expression

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Upsides and downsides to polarity and asymmetric cell division in leukemia.

31 March 2020

1 reference

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Drosophila asymmetric division, polarity and cancer

31 March 2020

1 reference

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Cell polarity proteins: common targets for tumorigenic human viruses

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Analysis of chromosomal changes in serous ovarian carcinoma using high-resolution array comparative genomic hybridization: Potential predictive markers of chemoresistant disease

31 March 2020

1 reference

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Expression of Hugl-1 is strongly reduced in malignant melanoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Array CGH identifies distinct DNA copy number profiles of oncogenes and tumor suppressor genes in chromosomal- and microsatellite-unstable sporadic colorectal carcinomas

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

A Network of PDZ-Containing Proteins Regulates T Cell Polarity and Morphology during Migration and Immunological Synapse Formation

31 March 2020

1 reference

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Transcriptional regulation of cell polarity in EMT and cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Circletail, a new mouse mutant with severe neural tube defects: chromosomal localization and interaction with the loop-tail mutation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

The LAP family: a phylogenetic point of view

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

The transcriptional repressor ZEB1 promotes metastasis and loss of cell polarity in cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Human papillomaviruses, cervical cancer and cell polarity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

Linking cell cycle to asymmetric division: Aurora-A phosphorylates the Par complex to regulate Numb localization

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.341

31 March 2020

Identifiers

DOI

10.1038/ONC.2008.341

1 reference

Dimensions Publication ID

19 August 2017

0 references

1 reference