(Q37333623)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029941%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

review article

1 reference

title

Upsides and downsides to polarity and asymmetric cell division in leukemia (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029941%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference

asymmetric cell division

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029941%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

author name string

E D Hawkins

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029941%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

language of work or name

English

0 references

publication date

1 November 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029941%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029941%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

volume

27

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029941%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

issue

55

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029941%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

page(s)

7003-7017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19029941%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/onc.2008.350

17 January 2020

exact match

0 references

cites work

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The Notch regulator Numb links the Notch and TCR signaling pathways

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Engagement of specific T-cell surface molecules regulates cytoskeletal polarization in HTLV-1-infected lymphocytes.

21 January 2018

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Asymmetric cell division within the human hematopoietic stem and progenitor cell compartment: identification of asymmetrically segregating proteins.

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Dare to be different: asymmetric cell division in Drosophila, C. elegans and vertebrates

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Asymmetric segregation of the tumor suppressor brat regulates self-renewal in Drosophila neural stem cells.

21 January 2018

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Localization-dependent and -independent roles of numb contribute to cell-fate specification in Drosophila

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Epithelial polarity and proliferation control: links from the Drosophila neoplastic tumor suppressors

21 January 2018

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Human Dlg protein binds to the envelope glycoproteins of human T-cell leukemia virus type 1 and regulates envelope mediated cell-cell fusion in T lymphocytes

21 January 2018

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Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

21 January 2018

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The tumor suppressors Brat and Numb regulate transit-amplifying neuroblast lineages in Drosophila

21 January 2018

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The hunt for cancer-initiating cells: a history stemming from leukemia

21 January 2018

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Asymmetric T lymphocyte division in the initiation of adaptive immune responses.

21 January 2018

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Bcr-Abl stabilizes beta-catenin in chronic myeloid leukemia through its tyrosine phosphorylation

21 January 2018

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Phosphoinositides specify polarity during epithelial organ development

21 January 2018

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Divide and conquer: how asymmetric division shapes cell fate in the hematopoietic system

21 January 2018

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Sustained and dynamic inositol lipid metabolism inside and outside the immunological synapse

21 January 2018

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From endocytosis to tumors through asymmetric cell division of stem cells.

21 January 2018

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Beyond PTEN mutations: the PI3K pathway as an integrator of multiple inputs during tumorigenesis

21 January 2018

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Regulation of Lethal giant larvae by Dishevelled

21 January 2018

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TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms

21 January 2018

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Cdc42 regulates GSK-3beta and adenomatous polyposis coli to control cell polarity

21 January 2018

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Cdc42 and Par6-PKCzeta regulate the spatially localized association of Dlg1 and APC to control cell polarization.

21 January 2018

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Alteration of phosphatidylinositol 3-kinase cascade in the multilobulated nuclear formation of adult T cell leukemia/lymphoma (ATLL)

21 January 2018

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The Par polarity complex regulates Rap1- and chemokine-induced T cell polarization

21 January 2018

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RhoA and zeta PKC control distinct modalities of LFA-1 activation by chemokines: critical role of LFA-1 affinity triggering in lymphocyte in vivo homing

21 January 2018

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Primitive human hematopoietic cells give rise to differentially specified daughter cells upon their initial cell division.

21 January 2018

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Planar cell polarity signalling controls cell division orientation during zebrafish gastrulation

21 January 2018

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Spindle orientation, asymmetric division and tumour suppression in Drosophila stem cells

21 January 2018

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Notch 1 activation in the molecular pathogenesis of T-cell acute lymphoblastic leukaemia

21 January 2018

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Multi-genetic events collaboratively contribute to Pten-null leukaemia stem-cell formation

21 January 2018

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Beta-catenin stabilization stalls the transition from double-positive to single-positive stage and predisposes thymocytes to malignant transformation

21 January 2018

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PTEN functions to 'prioritize' chemotactic cues and prevent 'distraction' in migrating neutrophils

21 January 2018

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Molecular requirements for epithelial-mesenchymal transition during tumor progression

21 January 2018

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Dlg, Scribble and Lgl in cell polarity, cell proliferation and cancer

21 January 2018

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The Scribble and Par complexes in polarity and migration: friends or foes?

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2008.350

Spread of HTLV-I between lymphocytes by virus-induced polarization of the cytoskeleton

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2008.350

Temporal and spatial regulation of chemotaxis

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2008.350

The APC-hDLG complex negatively regulates cell cycle progression from the G0/G1 to S phase

21 January 2018

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Chemotherapy-resistant human AML stem cells home to and engraft within the bone-marrow endosteal region.

21 January 2018

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Scribble associates with two polarity proteins, Lgl2 and Vangl2, via distinct molecular domains

21 January 2018

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Human scribble accumulates in colorectal neoplasia in association with an altered distribution of beta-catenin

21 January 2018

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Uncertainty in the niches that maintain haematopoietic stem cells

21 January 2018

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Loss of cell polarity causes severe brain dysplasia in Lgl1 knockout mice

21 January 2018

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Mechanisms of asymmetric stem cell division

21 January 2018

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Maintenance and modulation of T cell polarity

21 January 2018

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Thymic microenvironments for T cell differentiation and selection.

21 January 2018

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Lethal giant larvae controls the localization of notch-signaling regulators numb, neuralized, and Sanpodo in Drosophila sensory-organ precursor cells

21 January 2018

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In childhood acute lymphoblastic leukemia, blasts at different stages of immunophenotypic maturation have stem cell properties

21 January 2018

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Drosophila Aurora-A kinase inhibits neuroblast self-renewal by regulating aPKC/Numb cortical polarity and spindle orientation.

21 January 2018

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Lgl, Pins and aPKC regulate neuroblast self-renewal versus differentiation.

21 January 2018

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Cell polarity and cancer--cell and tissue polarity as a non-canonical tumor suppressor.

21 January 2018

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Discs-Large and Strabismus are functionally linked to plasma membrane formation

21 January 2018

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Normal stem cells and cancer stem cells: the niche matters

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2008.350

Directional sensing requires G beta gamma-mediated PAK1 and PIX alpha-dependent activation of Cdc42.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.350

Activation of the Wnt signaling pathway in chronic lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.350

PTEN-mediated apical segregation of phosphoinositides controls epithelial morphogenesis through Cdc42.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.350

The emerging role of Wnt signaling in the pathogenesis of acute myeloid leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.350

Cortical beta-catenin and APC regulate asymmetric nuclear beta-catenin localization during asymmetric cell division in C. elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.350

Two betas or not two betas: regulation of asymmetric division by beta-catenin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.350

Identification of Vangl2 and Scrb1 as planar polarity genes in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.350

Asymmetric and symmetric stem-cell divisions in development and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.350

Stem cells and niches: mechanisms that promote stem cell maintenance throughout life

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.350

Molecular and cellular aspects of HTLV-1 associated leukemogenesis in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.350

Bone marrow trephine morphology and immunohistochemical findings in chronic myelomonocytic leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.350

Myelodysplastic syndromes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.350

Control of cell polarity and motility by the PtdIns(3,4,5)P3 phosphatase SHIP1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.350

Role of cortical tumour-suppressor proteins in asymmetric division of Drosophila neuroblast

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.350

Generation of germline-competent induced pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.350

Ligation of the cell surface receptor, CD46, alters T cell polarity and response to antigen presentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.350

Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.350

The tumour-suppressor genes lgl and dlg regulate basal protein targeting in Drosophila neuroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.350

A novel role for Lef-1, a central transcription mediator of Wnt signaling, in leukemogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.350

Wnt signaling in the stem cell niche

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.350

Stem cells, cancer, and cancer stem cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2008.350

Regulation of membrane localization of Sanpodo by lethal giant larvae and neuralized in asymmetrically dividing cells of Drosophila sensory organs

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2008.350

Epigenetic regulation of Wnt-signaling pathway in acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.350

Launching the T-cell-lineage developmental programme

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.350

Dlgh1 coordinates actin polymerization, synaptic T cell receptor and lipid raft aggregation, and effector function in T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.350

How polarity shapes the destiny of T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.350

G protein betagamma subunits and AGS3 control spindle orientation and asymmetric cell fate of cerebral cortical progenitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.350

Getting to the stem of chronic myeloid leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.350

Cdc42 and noncanonical Wnt signal transduction pathways cooperate to promote cell polarity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.350

Acute lymphoblastic leukemia–hand mirror variant. An analysis of a large group of patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.350

Microtubule-induced Pins/Galphai cortical polarity in Drosophila neuroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.350

Location, location, location: the cancer stem cell niche

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.350

WNT signalling in the immune system: WNT is spreading its wings

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.350

Contributions of the Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways to leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.350

DLGH1 is a negative regulator of T-lymphocyte proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.350

Secretory mechanisms in cell-mediated cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.350

Asymmetric division and lineage commitment at the level of hematopoietic stem cells: inference from differentiation in daughter cell and granddaughter cell pairs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.350

WGEF activates Rho in the Wnt-PCP pathway and controls convergent extension in Xenopus gastrulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.350

Complex networks orchestrate epithelial-mesenchymal transitions

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2008.350

PtdIns(3,4,5)P3 regulates spindle orientation in adherent cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.350

To stabilize neutrophil polarity, PIP3 and Cdc42 augment RhoA activity at the back as well as signals at the front

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2008.350

Additional prognostic value of bone marrow histology in patients subclassified according to the International Prognostic Scoring System for myelodysplastic syndromes.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2008.350

Direct association of Bazooka/PAR-3 with the lipid phosphatase PTEN reveals a link between the PAR/aPKC complex and phosphoinositide signaling

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2008.350

Lipid products of PI(3)Ks maintain persistent cell polarity and directed motility in neutrophils

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2008.350

Development of Notch-dependent T-cell leukemia by deregulated Rap1 signaling

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2008.350

Notch and Wnt signaling in T-lymphocyte development and acute lymphoblastic leukemia

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2008.350

Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2008.350

In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2008.350

An ancient role for nuclear beta-catenin in the evolution of axial polarity and germ layer segregation.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2008.350

PDZ domains of Par-3 as potential phosphoinositide signaling integrators

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2008.350

Imaging hematopoietic precursor division in real time

21 January 2018

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Discs large (Dlg1) complexes in lymphocyte activation

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2008.350

Normal development is an integral part of tumorigenesis in T cell-specific PTEN-deficient mice

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2008.350

Orientation of asymmetric stem cell division by the APC tumor suppressor and centrosome.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2008.350

Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2008.350

CCR7 expression in developing thymocytes is linked to the CD4 versus CD8 lineage decision.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2008.350

Knockdown of synapse-associated protein Dlg1 reduces syncytium formation induced by human T-cell leukemia virus type 1.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2008.350

Expression of beta-catenin by acute myeloid leukemia cells predicts enhanced clonogenic capacities and poor prognosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.350

Loss of beta-catenin impairs the renewal of normal and CML stem cells in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.350

Cell polarity: an examination of its behavioral expression and its consequences for polymorphonuclear leukocyte chemotaxis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.350

PTEN is inversely correlated with the cell survival factor Akt/PKB and is inactivated via multiple mechanismsin haematological malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.350

PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.350

Distinct patterns of hematopoietic stem cell involvement in acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.350

Par complex in cancer: a regulator of normal cell polarity joins the dark side

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.350

Cutting edge: hierarchy of chemokine receptor and TCR signals regulating T cell migration and proliferation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.350

Regulation of T cell migration through formation of immunological synapses: the stop signal hypothesis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.350

Notch, a universal arbiter of cell fate decisions

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.350

Polarity proteins in migration and invasion

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.350

The long and the short of Wnt signaling in C. elegans

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.350

LKB1; linking cell structure and tumor suppression

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.350

Control of tumourigenesis by the Scribble/Dlg/Lgl polarity module

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.350

Drosophila asymmetric division, polarity and cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.350

Cell polarity proteins: common targets for tumorigenic human viruses

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.350

Identification of genes required for cytoplasmic localization in early C. elegans embryos

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.350

A Network of PDZ-Containing Proteins Regulates T Cell Polarity and Morphology during Migration and Immunological Synapse Formation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.350

Transcriptional regulation of cell polarity in EMT and cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.350

Hand-mirror blast cells in acute leukemia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.350

Cutting edge: Atypical PKCs regulate T lymphocyte polarity and scanning behavior

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.350

Human papillomaviruses, cervical cancer and cell polarity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.350

Stem cells and their niche: an inseparable relationship

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.350