(Q39643761)

English

The dicarboxylate carrier plays a role in mitochondrial malate transport and in the regulation of glucose-stimulated insulin secretion from rat pancreatic beta cells

scientific article published on 15 October 2010

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

The dicarboxylate carrier plays a role in mitochondrial malate transport and in the regulation of glucose-stimulated insulin secretion from rat pancreatic beta cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

author name string

P Huypens

1

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

R Pillai

2

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

T Sheinin

3

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

S Schaefer

4

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

M Huang

5

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

M L Odegaard

6

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

S M Ronnebaum

7

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

S D Wettig

8

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

J W Joseph

9

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

publication date

15 October 2010

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

54

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

135-145

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

https://scigraph.springernature.com/pub.10.1007/s00125-010-1923-5

0 references

Regulation of pancreatic beta-cell mitochondrial metabolism: influence of Ca2+, substrate and ADP.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-010-1923-5

21 January 2018

Studies with leucine, beta-hydroxybutyrate and ATP citrate lyase-deficient beta cells support the acetoacetate pathway of insulin secretion

1 reference

https://api.crossref.org/works/10.1007%2FS00125-010-1923-5

21 January 2018

Both triggering and amplifying pathways contribute to fuel-induced insulin secretion in the absence of sulfonylurea receptor-1 in pancreatic beta-cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic suppression of acetyl-CoA carboxylase 1 in beta-cells impairs insulin secretion via inhibition of glucose rather than lipid metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Normal flux through ATP-citrate lyase or fatty acid synthase is not required for glucose-stimulated insulin secretion.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucose-sensing mechanisms in pancreatic beta-cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired anaplerosis and insulin secretion in insulinoma cells caused by small interfering RNA-mediated suppression of pyruvate carboxylase

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain fatty acid synthase activates PPARalpha to maintain energy homeostasis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Establishment of 2-mercaptoethanol-dependent differentiated insulin-secreting cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Redox control of exocytosis: regulatory role of NADPH, thioredoxin, and glutaredoxin

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytosolic and mitochondrial malic enzyme isoforms differentially control insulin secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hierarchy of the beta-cell signals controlling insulin secretion.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucose and pharmacological modulators of ATP-sensitive K+ channels control [Ca2+]c by different mechanisms in isolated mouse alpha-cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Compensatory responses to pyruvate carboxylase suppression in islet beta-cells. Preservation of glucose-stimulated insulin secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mitochondrial transporter family (SLC25): physiological and pathological implications

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantifying the carboxylation of pyruvate in pancreatic islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Malonyl-CoA and long chain acyl-CoA esters as metabolic coupling factors in nutrient-induced insulin secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A role for malonyl-CoA in glucose-stimulated insulin secretion from clonal pancreatic beta-cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathways in beta-cell stimulus-secretion coupling as targets for therapeutic insulin secretagogues

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A role for ATP-citrate lyase, malic enzyme, and pyruvate/citrate cycling in glucose-induced insulin secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of insulin secretion: a matter of phase control and amplitude modulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mitochondrial 2-oxoglutarate carrier is part of a metabolic pathway that mediates glucose- and glutamine-stimulated insulin secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glycerolipid metabolism and signaling in health and disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic reduction of the cytosolic or mitochondrial NAD(P)-malic enzyme does not affect insulin secretion in a rat insulinoma cell line

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Temperature and redox state dependence of native Kv2.1 currents in rat pancreatic beta-cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta-cell alpha-ketoglutarate hydroxylases may acutely participate in insulin secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Feasibility of a mitochondrial pyruvate malate shuttle in pancreatic islets. Further implication of cytosolic NADPH in insulin secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolic control of beta-cell function

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The characterization of mitochondrial permeability transition in clonal pancreatic beta-cells. Multiple modes and regulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Perspective: emerging evidence for signaling roles of mitochondrial anaplerotic products in insulin secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucose controls cytosolic Ca2+ and insulin secretion in mouse islets lacking adenosine triphosphate-sensitive K+ channels owing to a knockout of the pore-forming subunit Kir6.2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Free fatty acid-induced beta-cell defects are dependent on uncoupling protein 2 expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Banting lecture 2001: dysregulation of fatty acid metabolism in the etiology of type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolic cycling in control of glucose-stimulated insulin secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estimates of glycolysis, pyruvate (de)carboxylation, pentose phosphate pathway, and methyl succinate metabolism in incapacitated pancreatic islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

13C NMR isotopomer analysis of anaplerotic pathways in INS-1 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucose stimulates Ca2+ influx and insulin secretion in 2-week-old beta-cells lacking ATP-sensitive K+ channels

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mitochondrial citrate/isocitrate carrier plays a regulatory role in glucose-stimulated insulin secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Malic enzyme is present in mouse islets and modulates insulin secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

13C NMR isotopomer analysis reveals a connection between pyruvate cycling and glucose-stimulated insulin secretion (GSIS)

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation of INS-1-derived cell lines with robust ATP-sensitive K+ channel-dependent and -independent glucose-stimulated insulin secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Feasibility of pathways for transfer of acyl groups from mitochondria to the cytosol to form short chain acyl-CoAs in the pancreatic beta cell

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alpha-Ketoisocaproate-induced hypersecretion of insulin by islets from diabetes-susceptible mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence that glucose can control insulin release independently from its action on ATP-sensitive K+ channels in mouse B cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A pyruvate cycling pathway involving cytosolic NADP-dependent isocitrate dehydrogenase regulates glucose-stimulated insulin secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacological stimulation and inhibition of insulin secretion in mouse islets lacking ATP-sensitive K+ channels

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adenine nucleotide pattern in rat pancreatic islets exposed to nutrient secretagogues

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dual Functional Role of Membrane Depolarization/Ca2+ Influx in Rat Pancreatic B-Cell

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolic fate of glucose in purified islet cells. Glucose-regulated anaplerosis in beta cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Electrophysiology of the pancreatic beta-cell

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overnight culture unmasks glucose-induced insulin secretion in mouse islets lacking ATP-sensitive K+ channels by improving the triggering Ca2+ signal

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Shortcomings of current models of glucose-induced insulin secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Silencing of cytosolic or mitochondrial isoforms of malic enzyme has no effect on glucose-stimulated insulin secretion from rodent islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of glutamate generation in mitochondria affects hormone secretion in INS-1E beta cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anaplerosis from glucose, alpha-ketoisocaproate, and pyruvate in pancreatic islets, INS-1 cells and liver mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for the malate aspartate shuttle in pancreatic islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Non-heme dioxygenases: cellular sensors and regulators jelly rolled into one?

1 reference

https://pubmed.ncbi.nlm.nih.gov/20949348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00125-010-1923-5

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q39643761&oldid=1849766437"