(Q37415411)

20 August 2017

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title

Regulation of insulin secretion: a matter of phase control and amplitude modulation (English)

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20 August 2017

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J C Henquin

1

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20 August 2017

publication date

14 March 2009

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20 August 2017

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20 August 2017

volume

52

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20 August 2017

issue

5

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20 August 2017

page(s)

739-751

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https://scigraph.springernature.com/pub.10.1007/s00125-009-1314-y

20 August 2017

exact match

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cites work

Rapid ATP-Dependent Priming of Secretory Granules Precedes Ca2+-Induced Exocytosis in Mouse Pancreatic B-Cells

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12 December 2020

Both triggering and amplifying pathways contribute to fuel-induced insulin secretion in the absence of sulfonylurea receptor-1 in pancreatic beta-cells

1 reference

12 December 2020

Widespread synchronous [Ca2+]i oscillations due to bursting electrical activity in single pancreatic islets

1 reference

12 December 2020

In vivo and in vitro glucose-induced biphasic insulin secretion in the mouse: pattern and role of cytoplasmic Ca2+ and amplification signals in beta-cells

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12 December 2020

Insulin granule dynamics in pancreatic beta cells

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12 December 2020

Glucose-regulated pulsatile insulin release from mouse islets via the K(ATP) channel-independent pathway

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12 December 2020

Redox control of exocytosis: regulatory role of NADPH, thioredoxin, and glutaredoxin

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12 December 2020

Metabolic and electrical oscillations: partners in controlling pulsatile insulin secretion

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12 December 2020

Islet-cell-to-cell communication as basis for normal insulin secretion

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12 December 2020

Nutrient control of insulin secretion in isolated normal human islets

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12 December 2020

Loss of connexin36 channels alters beta-cell coupling, islet synchronization of glucose-induced Ca2+ and insulin oscillations, and basal insulin release.

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12 December 2020

Oscillatory control of insulin secretion

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12 December 2020

Identifying the targets of the amplifying pathway for insulin secretion in pancreatic beta-cells by kinetic modeling of granule exocytosis.

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12 December 2020

Insulin secretion in the conscious mouse is biphasic and pulsatile

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12 December 2020

Hierarchy of the beta-cell signals controlling insulin secretion.

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12 December 2020

Mechanisms by which glucose can control insulin release independently from its action on adenosine triphosphate-sensitive K+ channels in mouse B cells

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12 December 2020

Glucose acutely decreases pH of secretory granules in mouse pancreatic islets. Mechanisms and influence on insulin secretion

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12 December 2020

Anaplerotic input is sufficient to induce time-dependent potentiation of insulin release in rat pancreatic islets

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12 December 2020

Metabolic oscillations in beta-cells

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12 December 2020

Metabolic regulation of the pancreatic beta-cell ATP-sensitive K+ channel: a pas de deux

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12 December 2020

Pathways in beta-cell stimulus-secretion coupling as targets for therapeutic insulin secretagogues

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12 December 2020

Measurements of cytoplasmic Ca2+ in islet cell clusters show that glucose rapidly recruits beta-cells and gradually increases the individual cell response

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12 December 2020

Diverse roles of K(ATP) channels learned from Kir6.2 genetically engineered mice

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12 December 2020

Modeling phasic insulin release: immediate and time-dependent effects of glucose

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12 December 2020

Glucose both inhibits and stimulates insulin secretion from isolated pancreatic islets exposed to maximally effective concentrations of sulfonylureas

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12 December 2020

Glucose-dependent increase in mitochondrial membrane potential, but not cytoplasmic calcium, correlates with insulin secretion in single islet cells

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12 December 2020

Tolbutamide stimulation of pancreatic beta-cells involves both cell recruitment and increase in the individual Ca(2+) response

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12 December 2020

The elevation of glutamate content and the amplification of insulin secretion in glucose-stimulated pancreatic islets are not causally related

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12 December 2020

Glucose-stimulated oscillations in free cytosolic ATP concentration imaged in single islet beta-cells: evidence for a Ca2+-dependent mechanism

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12 December 2020

Signals and pools underlying biphasic insulin secretion

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12 December 2020

Oscillations of insulin secretion can be triggered by imposed oscillations of cytoplasmic Ca2+ or metabolism in normal mouse islets

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12 December 2020

The in vivo regulation of pulsatile insulin secretion

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12 December 2020

Sulphonylurea action revisited: the post-cloning era.

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12 December 2020

Concentration dependence and time course of the effects of glucose on adenine and guanine nucleotides in mouse pancreatic islets

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12 December 2020

Glucose modulates [Ca2+]i oscillations in pancreatic islets via ionic and glycolytic mechanisms

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12 December 2020

ATP-sensitive K+ channels may control glucose-induced electrical activity in pancreatic B-cells

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12 December 2020

Toward linking structure with function in ATP-sensitive K+ channels

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12 December 2020

Regulation of insulin secretion studied with pieces of rabbit pancreas incubated in vitro

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12 December 2020

Triggering and amplifying pathways of regulation of insulin secretion by glucose

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12 December 2020

Glucose activates both K(ATP) channel-dependent and K(ATP) channel-independent signaling pathways in human islets

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12 December 2020

Mitochondrial function in normal and diabetic beta-cells

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12 December 2020

Distinct effects of glucose on the synchronous oscillations of insulin release and cytoplasmic Ca2+ concentration measured simultaneously in single mouse islets

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12 December 2020

CaV2.3 calcium channels control second-phase insulin release

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12 December 2020

The AMP-regulated kinase family: enigmatic targets for diabetes therapy

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12 December 2020

Glucose controls cytosolic Ca2+ and insulin secretion in mouse islets lacking adenosine triphosphate-sensitive K+ channels owing to a knockout of the pore-forming subunit Kir6.2.

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12 December 2020

Regulation of the expression of components of the exocytotic machinery of insulin-secreting cells by microRNAs

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12 December 2020

KATP channels as molecular sensors of cellular metabolism

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12 December 2020

Quantitative subcellular imaging of glucose metabolism within intact pancreatic islets

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12 December 2020

Docking is not a prerequisite but a temporal constraint for fusion of secretory granules

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12 December 2020

Modeling of Ca2+ flux in pancreatic beta-cells: role of the plasma membrane and intracellular stores

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12 December 2020

Significance of ionic fluxes and changes in membrane potential for stimulus-secretion coupling in pancreatic B-cells

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12 December 2020

The permissive effect of glucose, tolbutamide and high K+ on arginine stimulation of insulin release in isolated mouse islets

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12 December 2020

Imaging analysis reveals mechanistic differences between first- and second-phase insulin exocytosis

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12 December 2020

Glucose-stimulated signaling pathways in biphasic insulin secretion

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12 December 2020

Inositol (1,4,5)-trisphosphate dynamics and intracellular calcium oscillations in pancreatic beta-cells

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12 December 2020

Molecular mechanisms and regulation of insulin exocytosis as a paradigm of endocrine secretion

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12 December 2020

Electrophysiological evidence for coupling between beta cells of pancreatic islets

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12 December 2020

Metabolic cycling in control of glucose-stimulated insulin secretion

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12 December 2020

EFFECTS OF CARBOHYDRATES ON SECRETION OF INSULIN FROM ISOLATED RAT PANCREAS

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12 December 2020

Do oscillations of insulin secretion occur in the absence of cytoplasmic Ca2+ oscillations in beta-cells?

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12 December 2020

Glucose stimulates Ca2+ influx and insulin secretion in 2-week-old beta-cells lacking ATP-sensitive K+ channels

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12 December 2020

Relative contribution of Ca2+-dependent and Ca2+-independent mechanisms to the regulation of insulin secretion by glucose

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12 December 2020

Oscillations in cytosolic free Ca2+, oxygen consumption, and insulin secretion in glucose-stimulated rat pancreatic islets

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12 December 2020

Insulin secretion in diabetes mellitus

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12 December 2020

Ca2+ controls slow NAD(P)H oscillations in glucose-stimulated mouse pancreatic islets.

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12 December 2020

Isolation of INS-1-derived cell lines with robust ATP-sensitive K+ channel-dependent and -independent glucose-stimulated insulin secretion

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12 December 2020

Synaptotagmins bind calcium to release insulin.

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12 December 2020

Sur1 knockout mice. A model for K(ATP) channel-independent regulation of insulin secretion

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12 December 2020

Parallel oscillations of intracellular calcium activity and mitochondrial membrane potential in mouse pancreatic B-cells.

1 reference

12 December 2020

Fuel-induced amplification of insulin secretion in mouse pancreatic islets exposed to a high sulfonylurea concentration: role of the NADPH/NADP+ ratio

1 reference

12 December 2020

Delay between fusion pore opening and peptide release from large dense-core vesicles in neuroendocrine cells

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12 December 2020

Nutrient control of insulin secretion in perifused adult pig islets

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12 December 2020

Evidence that glucose can control insulin release independently from its action on ATP-sensitive K+ channels in mouse B cells

1 reference

12 December 2020

Dual mechanism of the potentiation by glucose of insulin secretion induced by arginine and tolbutamide in mouse islets

1 reference

12 December 2020

Post-priming actions of ATP on Ca2+-dependent exocytosis in pancreatic beta cells

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12 December 2020

Glucose-induced amplitude regulation of pulsatile insulin secretion from individual pancreatic islets

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12 December 2020

Dual Functional Role of Membrane Depolarization/Ca2+ Influx in Rat Pancreatic B-Cell

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12 December 2020

Involvement of conventional kinesin in glucose-stimulated secretory granule movements and exocytosis in clonal pancreatic beta-cells.

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12 December 2020

Electrophysiology of the pancreatic beta-cell

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12 December 2020

Heterogeneity in Pancreatic β-cell Population

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12 December 2020

Essential role of Epac2/Rap1 signaling in regulation of insulin granule dynamics by cAMP.

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12 December 2020

Effect of loss of first-phase insulin secretion on hepatic glucose production and tissue glucose disposal in humans

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12 December 2020

Dynamics of Insulin Secretion by the Perfused Rat Pancreas

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12 December 2020

Two sites of glucose control of insulin release with distinct dependence on the energy state in pancreatic B-cells

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12 December 2020

Time and amplitude regulation of pulsatile insulin secretion by triggering and amplifying pathways in mouse islets

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12 December 2020

Glucose-induced cyclic AMP oscillations regulate pulsatile insulin secretion.

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12 December 2020

Electrical activity in pancreatic islet cells

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12 December 2020

Comparison of storage- and signal-limited models of pancreatic insulin secretion.

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12 December 2020

Temporal and quantitative correlations between insulin secretion and stably elevated or oscillatory cytoplasmic Ca2+ in mouse pancreatic beta-cells.

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12 December 2020

Defective insulin secretion and enhanced insulin action in KATP channel-deficient mice.

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12 December 2020

Pulsatile insulin secretion by human pancreatic islets

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12 December 2020

The plasma insulin response to glucose infusion in healthy subjects and in diabetes mellitus

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12 December 2020

Synchronization and entrainment of cytoplasmic Ca2+ oscillations in cell clusters prepared from single or multiple mouse pancreatic islets

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12 December 2020

Control mechanisms of the oscillations of insulin secretion in vitro and in vivo

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12 December 2020

Insulin granule trafficking in beta-cells: mathematical model of glucose-induced insulin secretion.

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12 December 2020

Glucose-induced oscillatory insulin secretion in perifused rat pancreatic islets and clonal beta-cells (HIT).

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12 December 2020

KATP channel-independent glucose action: an elusive pathway in stimulus-secretion coupling of pancreatic beta-cell

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12 December 2020

Glucose stimulation of insulin release in the absence of extracellular Ca2+ and in the absence of any increase in intracellular Ca2+ in rat pancreatic islets.

1 reference

12 December 2020

10.1007/S00125-009-1314-Y

Identifiers

DOI

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20 August 2017

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