(Q39646265)

13 September 2017

title

TGFβ induces proHB-EGF shedding and EGFR transactivation through ADAM activation in gastric cancer cells (English)

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13 September 2017

3

Takaya Shimura

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20934403

30 July 2024

author name string

Masahide Ebi

1

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13 September 2017

Hiromi Kataoka

2

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13 September 2017

Eiji Kubota

4

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13 September 2017

Yoshikazu Hirata

5

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13 September 2017

Takashi Mizushima

6

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13 September 2017

Tsutomu Mizoshita

7

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13 September 2017

Mamoru Tanaka

8

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13 September 2017

Motoshi Mabuchi

9

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13 September 2017

Hironobu Tsukamoto

10

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13 September 2017

Satoshi Tanida

11

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13 September 2017

Takeshi Kamiya

12

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13 September 2017

Shigeki Higashiyama

13

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13 September 2017

Takashi Joh

14

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13 September 2017

language of work or name

English

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publication date

8 October 2010

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full work available at URL

13 September 2017

https://api.elsevier.com/content/article/PII:S0006291X10018528?httpAccept=text/xml

1 reference

https://api.crossref.org/works/10.1016/J.BBRC.2010.09.130

https://api.elsevier.com/content/article/PII:S0006291X10018528?httpAccept=text/plain

30 July 2024

1 reference

https://api.crossref.org/works/10.1016/J.BBRC.2010.09.130

Biochemical and Biophysical Research Communications

30 July 2024

published in

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13 September 2017

volume

402

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13 September 2017

issue

3

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13 September 2017

page(s)

449-454

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Type beta transforming growth factor: a bifunctional regulator of cellular growth

13 September 2017

cites work

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TGF-beta signaling, tumor suppression, and acute lymphoblastic leukemia

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EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF

30 July 2024

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Cardiac hypertrophy is inhibited by antagonism of ADAM12 processing of HB-EGF: metalloproteinase inhibitors as a new therapy

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Tyrosine phosphorylation of the EGF receptor by the kinase Jak2 is induced by growth hormone

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A Heparin-Binding Growth Factor Secreted by Macrophage-Like Cells That Is Related to EGF

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Epidermal growth factor receptor (EGFR) and EGFR mutations, function and possible role in clinical trials

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Epidermal growth factor receptor mediates increased cell proliferation, migration, and aggregation in esophageal keratinocytes in vitro and in vivo

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The mechanism of cleavage of EGFR ligands induced by inflammatory cytokines in gastric cancer cells

30 July 2024

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Helicobacter pylori-stimulated interleukin-8 (IL-8) promotes cell proliferation through transactivation of epidermal growth factor receptor (EGFR) by disintegrin and metalloproteinase (ADAM) activation

30 July 2024

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Oxidative and osmotic stress signaling in tumor cells is mediated by ADAM proteases and heparin-binding epidermal growth factor

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Distinct ADAM metalloproteinases regulate G protein-coupled receptor-induced cell proliferation and survival

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Proteolytic release of the carboxy-terminal fragment of proHB-EGF causes nuclear export of PLZF

30 July 2024

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ADAM-mediated ectodomain shedding of HB-EGF in receptor cross-talk

30 July 2024

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Membrane-anchored growth factors, the epidermal growth factor family: beyond receptor ligands

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Suppression of proHB-EGF carboxy-terminal fragment nuclear translocation: a new molecular target therapy for gastric cancer.

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EGFR ligands and their signaling scissors, ADAMs, as new molecular targets for anticancer treatments

30 July 2024

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BCL6 degradation caused by the interaction with the C-terminus of pro-HB-EGF induces cyclin D2 expression in gastric cancers.

30 July 2024

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Transforming growth factorbeta(1) transactivates EGFR via an H(2)O(2)-dependent mechanism in squamous carcinoma cell line

30 July 2024

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Involvement of EGF receptor and c-Src in the survival signals induced by TGF-beta1 in hepatocytes

30 July 2024

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Involvement of HB-EGF and EGF receptor transactivation in TGF-beta-mediated fibronectin expression in mesangial cells

30 July 2024

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Activation of NADPH oxidase by transforming growth factor-beta in hepatocytes mediates up-regulation of epidermal growth factor receptor ligands through a nuclear factor-kappaB-dependent mechanism

30 July 2024

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Transforming growth factor beta engages TACE and ErbB3 to activate phosphatidylinositol-3 kinase/Akt in ErbB2-overexpressing breast cancer and desensitizes cells to trastuzumab

30 July 2024

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Ectodomain shedding of epidermal growth factor receptor ligands is required for keratinocyte migration in cutaneous wound healing

30 July 2024

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ADAMs in cancer cell proliferation and progression.

30 July 2024

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The ADAMs: signalling scissors in the tumour microenvironment

30 July 2024

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The two faces of transforming growth factor beta in carcinogenesis

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Tumour microenvironment: TGFbeta: the molecular Jekyll and Hyde of cancer

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Transforming growth factor-beta signaling in epithelial-mesenchymal transition and progression of cancer

30 July 2024

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Smad transcription factors

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Inactivation of SMAD4 tumor suppressor gene during gastric carcinoma progression

30 July 2024

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SMAD4 gene mutations are associated with poor prognosis in pancreatic cancer

30 July 2024

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TGF-beta has paradoxical and context dependent effects on proliferation and anoikis in human colorectal cancer cell lines

30 July 2024

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30 July 2024

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Diffuse-type gastric carcinoma: progression, angiogenesis, and transforming growth factor beta signaling

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Expression of TGF-beta and procollagen type I and type III in human gastric carcinomas

30 July 2024

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A novel transforming growth factor beta receptor kinase inhibitor, A-77, prevents the peritoneal dissemination of scirrhous gastric carcinoma

30 July 2024

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Establishment and characterization of a human scirrhus type gastric cancer cell line, GCIY, producing CA19-9

30 July 2024

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Dual intracellular signaling by proteolytic cleavage of membrane-anchored heparin-binding EGF-like growth factor

30 July 2024

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Ligand release-independent transactivation of epidermal growth factor receptor by transforming growth factor-beta involves multiple signaling pathways.

30 July 2024

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30 July 2024

Identifiers

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13 September 2017

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