(Q41718736)

8 October 2017

1 reference

title

Epidermal growth factor receptor (EGFR) and EGFR mutations, function and possible role in clinical trials (English)

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8 October 2017

B R Voldborg

1

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8 October 2017

L Damstrup

series ordinal

2

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8 October 2017

M Spang-Thomsen

series ordinal

3

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8 October 2017

H S Poulsen

series ordinal

4

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8 October 2017

language of work or name

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1 December 1997

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8 October 2017

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8 October 2017

8

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8 October 2017

1197-1206

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8 October 2017

12

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The epidermal growth factor (EGF).

8 October 2017

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1008209720526

7 January 2021

Epidermal growth factor induces rapid, reversible aggregation of the purified epidermal growth factor receptor

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1008209720526

7 January 2021

Binding of SH2 domains of phospholipase C gamma 1, GAP, and Src to activated growth factor receptors

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1008209720526

7 January 2021

Regulation of EGF receptor expression and function

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1008209720526

7 January 2021

Amphiregulin: a bifunctional growth-modulating glycoprotein produced by the phorbol 12-myristate 13-acetate-treated human breast adenocarcinoma cell line MCF-7

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1008209720526

7 January 2021

Betacellulin: a mitogen from pancreatic beta cell tumors

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1008209720526

7 January 2021

Amplified and rearranged epidermal growth factor receptor genes in human glioblastomas reveal deletions of sequences encoding portions of the N- and/or C-terminal tails

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1008209720526

7 January 2021

Identical splicing of aberrant epidermal growth factor receptor transcripts from amplified rearranged genes in human glioblastomas

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1008209720526

7 January 2021

Antibodies against a synthetic peptide as a probe for the kinase activity of the avian EGF receptor and v-erbB protein

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1008209720526

7 January 2021

Protein phosphorylation at tyrosine is induced by the v-erbB gene product in vivo and in vitro.

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1008209720526

7 January 2021

Deletion-mutant epidermal growth factor receptor in human gliomas: Effect of type II mutation on receptor function

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1008209720526

7 January 2021

A deletion mutation within the ligand binding domain is responsible for activation of epidermal growth factor receptor gene in human brain tumors

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1008209720526

7 January 2021

Structural alterations of the epidermal growth factor receptor gene in human gliomas

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1008209720526

7 January 2021

Anti-synthetic peptide antibody reacting at the fusion junction of deletion-mutant epidermal growth factor receptors in human glioblastoma

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1008209720526

7 January 2021

A mutant epidermal growth factor receptor common in human glioma confers enhanced tumorigenicity

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1008209720526

7 January 2021

The enhanced tumorigenic activity of a mutant epidermal growth factor receptor common in human cancers is mediated by threshold levels of constitutive tyrosine phosphorylation and unattenuated signaling

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1008209720526

7 January 2021

Specific targeting of a mutant, activated FGF receptor found in glioblastoma using a monoclonal antibody

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1008209720526

7 January 2021

Interaction of Heparin-Binding EGF-Like Growth Factor (HB-EGF) with the Epidermal Growth Factor Receptor: Modulation by Heparin, Heparinase, or Synthetic Heparin-Binding HB-EGF Fragments

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1008209720526

7 January 2021

The type 1 (EGFR-related) family of growth factor receptors and their ligands

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1008209720526

7 January 2021

Heterodimerization and functional interaction between EGF receptor family members: a new signaling paradigm with implications for breast cancer research

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1008209720526

7 January 2021

Requirement for the adapter protein GRB2 in EGF receptor endocytosis

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1008209720526

7 January 2021

Tumor promoters block tyrosine-specific phosphorylation of the epidermal growth factor receptor

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1008209720526

7 January 2021

Endocytosis and lysosomal targeting of epidermal growth factor receptors are mediated by distinct sequences independent of the tyrosine kinase domain

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1008209720526

7 January 2021

Functional independence of the epidermal growth factor receptor from a domain required for ligand-induced internalization and calcium regulation

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1008209720526

7 January 2021

Mutation of proline-1003 to glycine in the epidermal growth factor (EGF) receptor enhances responsiveness to EGF.

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1008209720526

7 January 2021

Signal transduction by receptors with tyrosine kinase activity

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1008209720526

7 January 2021

The molecular heterogeneity of protein kinase C and its implications for cellular regulation

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1008209720526

7 January 2021

PDGF induction of tyrosine phosphorylation of GTPase activating protein

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1008209720526

7 January 2021

Proteins regulating Ras and its relatives

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1008209720526

7 January 2021

Activation of the MAP kinase pathway by the protein kinase raf

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1008209720526

7 January 2021

https://api.crossref.org/works/10.1023%2FA%3A1008209720526

1 reference

7 January 2021

Cyclins and cancer. II: Cyclin D and CDK inhibitors come of age

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1008209720526

7 January 2021

Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin.

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1008209720526

7 January 2021

Characterization of epidermal growth factor receptor gene expression in malignant and normal human cell lines

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1008209720526

7 January 2021

Effect of epidermal growth factor on cadherin-mediated adhesion in a human oesophageal cancer cell line

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1008209720526

7 January 2021

Distribution of epidermal growth factor receptor gene amplification in brain tumours and correlation to prognosis.

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1008209720526

7 January 2021

EGF receptor expression in primary laryngeal cancer: correlation with clinico-pathological features and prognostic significance

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1008209720526

7 January 2021

A comparison of epidermal growth factor receptor levels and other prognostic parameters in non-small cell lung cancer.

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1008209720526

7 January 2021

Lack of prognostic significance of epidermal growth factor receptor and the oncoprotein p185HER-2 in patients with systemically untreated non-small-cell lung cancer: an immunohistochemical study on cryosections

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1008209720526

7 January 2021

The relationship of quantitative epidermal growth factor receptor expression in non-small cell lung cancer to long term survival

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1008209720526

7 January 2021

Expression of epidermal growth factor receptor (EGF-R) in non-small cell lung cancer. Use of archival tissue and correlation of EGF-R with histology, tumour size, node status and survival

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1008209720526

7 January 2021

Epidermal growth factor receptors in non-small cell lung cancer

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1008209720526

7 January 2021

Evidence for epidermal growth factor (EGF)-induced intermolecular autophosphorylation of the EGF receptors in living cells

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1008209720526

7 January 2021

A dominant negative mutation suppresses the function of normal epidermal growth factor receptors by heterodimerization

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1008209720526

7 January 2021

Trans receptor inhibition of human glioblastoma cells by erbB family ectodomains.

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1008209720526

7 January 2021

Tyrosine kinase inhibitor as a novel signal transduction and antiproliferative agent: prostate cancer

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1008209720526

7 January 2021

4-(Phenylamino)pyrrolopyrimidines: potent and selective, ATP site directed inhibitors of the EGF-receptor protein tyrosine kinase

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1008209720526

7 January 2021

Cytoskeletal and morphological changes associated with the specific suppression of the epidermal growth factor receptor tyrosine kinase activity in A431 human epidermoid carcinoma

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1008209720526

7 January 2021

Inhibition of the epidermal growth factor receptor tyrosine kinase by PD153035 in human A431 tumors in athymic nude mice

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1008209720526

7 January 2021

Blocking of EGF-dependent cell proliferation by EGF receptor kinase inhibitors

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1008209720526

7 January 2021

Tyrphostins--potential antiproliferative agents and novel molecular tools

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1008209720526

7 January 2021

Dianilinophthalimides: potent and selective, ATP-competitive inhibitors of the EGF-receptor protein tyrosine kinase

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1008209720526

7 January 2021

RETRACTED: 4,5-Dianilinophthalimide: a protein-tyrosine kinase inhibitor with selectivity for the epidermal growth factor receptor signal transduction pathway and potent in vivo antitumor activity

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1008209720526

7 January 2021

Malignant astrocytomas treated with iodine-125 labeled monoclonal antibody 425 against epidermal growth factor receptor: A phase II trial

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1008209720526

7 January 2021

Antitumor Activity of Combined Blockade of Epidermal Growth Factor Receptor and Protein Kinase A

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1008209720526

7 January 2021

Identifiers

DOI

10.1023/A:1008209720526

1 reference

8 October 2017

1 reference