(Q39656305)

13 September 2017

A critical role of integrin-linked kinase, ch-TOG and TACC3 in centrosome clustering in cancer cells (English)

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13 September 2017

A B Fielding

1

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13 September 2017

S Lim

2

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13 September 2017

K Montgomery

3

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13 September 2017

I Dobreva

4

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13 September 2017

S Dedhar

5

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13 September 2017

language of work or name

English

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publication date

13 September 2010

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13 September 2017

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13 September 2017

30

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13 September 2017

521-534

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13 September 2017

5

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https://scigraph.springernature.com/pub.10.1038/onc.2010.431

13 September 2017

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cites work

Xenopus TACC3/maskin is not required for microtubule stability but is required for anchoring microtubules at the centrosome

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.431

MCAK-independent functions of ch-Tog/XMAP215 in microtubule plus-end dynamics

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.431

Aurora A activates D-TACC-Msps complexes exclusively at centrosomes to stabilize centrosomal microtubules

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.431

Centrosome amplification can initiate tumorigenesis in flies.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.431

Genome-wide survey of protein kinases required for cell cycle progression.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.431

Managing the centrosome numbers game: from chaos to stability in cancer cell division

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.431

TOGp, the human homolog of XMAP215/Dis1, is required for centrosome integrity, spindle pole organization, and bipolar spindle assembly

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.431

Mapping the integrin-linked kinase interactome using SILAC.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.431

Suppression of VEGF secretion and changes in glioblastoma multiforme microenvironment by inhibition of integrin-linked kinase (ILK).

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.431

Integrin-linked kinase localizes to the centrosome and regulates mitotic spindle organization

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.431

Clonogenic assay of cells in vitro.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.431

A mechanism linking extra centrosomes to chromosomal instability

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.431

The ch-TOG/XMAP215 protein is essential for spindle pole organization in human somatic cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.431

Drosophila Aurora A kinase is required to localize D-TACC to centrosomes and to regulate astral microtubules.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.431

Loss of integrin linked kinase from mouse hepatocytes in vitro and in vivo results in apoptosis and hepatitis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.431

Liver cell polyploidization: a pivotal role for binuclear hepatocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.431

Integrin-linked kinase: a cancer therapeutic target unique among its ILK.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.431

Aurora A phosphorylation of TACC3/maskin is required for centrosome-dependent microtubule assembly in mitosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.431

Targeting integrin-linked kinase inhibits Akt signaling pathways and decreases tumor progression of human glioblastoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.431

Centrosome replication, genomic instability and cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.431

Mechanisms to suppress multipolar divisions in cancer cells with extra centrosomes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.431

Msps/XMAP215 interacts with the centrosomal protein D-TACC to regulate microtubule behaviour.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.431

ILK, PINCH and parvin: the tIPP of integrin signalling

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.431

Localization of human TACC3 to mitotic spindles is mediated by phosphorylation on Ser558 by Aurora A: a novel pharmacodynamic method for measuring Aurora A activity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.431

Centrosome amplification drives chromosomal instability in breast tumor development

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.431

Altered centrosome structure is associated with abnormal mitoses in human breast tumors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.431

Liver tetraploidization is controlled by a new process of incomplete cytokinesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.431

Integrin-linked kinase--essential roles in physiology and cancer biology.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.431

Origins and consequences of centrosome aberrations in human cancers

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.431

Centrosome aberrations: cause or consequence of cancer progression?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.431

Function and regulation of Maskin, a TACC family protein, in microtubule growth during mitosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.431

Spindle multipolarity is prevented by centrosomal clustering.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.431

Identification of griseofulvin as an inhibitor of centrosomal clustering in a phenotype-based screen

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.431

Mitosis in a cell with multiple centrioles

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.431

Multipolar spindle pole coalescence is a major source of kinetochore mis-attachment and chromosome mis-segregation in cancer cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.431

Identification of the substrates and interaction proteins of aurora kinases from a protein-protein interaction model

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.431

Preferential dependence of breast cancer cells versus normal cells on integrin-linked kinase for protein kinase B/Akt activation and cell survival

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.431

Migfilin and Mig-2 link focal adhesions to filamin and the actin cytoskeleton and function in cell shape modulation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.431

Centrosome amplification as a possible mechanism for numerical chromosome aberrations in cerebral primitive neuroectodermal tumors with TP53 mutations

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.431

Actin and microtubules: working together to control spindle polarity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.431

Expression of an amino-terminal BRCA1 deletion mutant causes a dominant growth inhibition in MCF10A cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.431

Centrosome function in cancer: guilty or innocent?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.431

31 March 2020

Identifiers

DOI

10.1038/ONC.2010.431

1 reference

Dimensions Publication ID

13 September 2017

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1 reference