(Q34622335)

3 August 2017

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title

Centrosome replication, genomic instability and cancer (English)

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3 August 2017

Krämer A

1

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3 August 2017

Neben K

series ordinal

2

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3 August 2017

Ho AD

series ordinal

3

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3 August 2017

1 May 2002

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3 August 2017

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3 August 2017

16

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3 August 2017

767-775

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3 August 2017

5

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https://scigraph.springernature.com/pub.10.1038/sj.leu.2402454

3 August 2017

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cites work

Genetic instabilities in human cancers

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Aneuploidy and cancer

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Genetic instability in colorectal cancers

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

DNA content as a prognostic marker in patients with oral leukoplakia.

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Cytogenetic comparisons of synchronous carcinomas and polyps in patients with colorectal cancer

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Cytogenetic analysis of colorectal adenomas: karyotypic comparisons of synchronous tumors.

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

DNA aneuploidy as a marker of premalignancy in surveillance of patients with ulcerative colitis

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Evolution of neoplastic cell lineages in Barrett oesophagus

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Aneuploidy correlated 100% with chemical transformation of Chinese hamster cells

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Image analysis of papillary thyroid carcinoma fine-needle aspirates: significant association between aneuploidy and death from disease

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

DNA aneuploidy by flow cytometry is an independent prognostic factor in gastric cancer.

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Trisomy 7-harbouring non-random duplication of the mutant MET allele in hereditary papillary renal carcinomas

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Acute myeloid leukemia

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Genetic instability of cancer cells is proportional to their degree of aneuploidy

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Identification of a vertebrate sister-chromatid separation inhibitor involved in transformation and tumorigenesis

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Control of apoptosis and mitotic spindle checkpoint by survivin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

A checkpoint on the road to cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Mutations of mitotic checkpoint genes in human cancers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

A role for the Adenomatous Polyposis Coli protein in chromosome segregation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Mutations in the APC tumour suppressor gene cause chromosomal instability

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Human T cell leukemia virus type 1 oncoprotein Tax targets the human mitotic checkpoint protein MAD1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Microtubule organizing centers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Centrosome structure and microtubule nucleation in animal cells

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

The centrosome and its role in the organization of microtubules

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Integrating centrosome structure with protein composition and function in animal cells

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

1 reference

7 January 2021

Re-evaluating centrosome function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Centriole disassembly in vivo and its effect on centrosome structure and function in vertebrate cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Centriole number and the reproductive capacity of spindle poles

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Reproductive capacity of sea urchin centrosomes without centrioles

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Planting the seeds of biotechnology

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

The mammalian gamma-tubulin complex contains homologues of the yeast spindle pole body components spc97p and spc98p

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Pericentrin and gamma-tubulin form a protein complex and are organized into a novel lattice at the centrosome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

The respective contributions of the mother and daughter centrioles to centrosome activity and behavior in vertebrate cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Spindle assembly in animal cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Zygotic development without functional mitotic centrosomes.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Requirement of a centrosomal activity for cell cycle progression through G1 into S phase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Centrosome-independent mitotic spindle formation in vertebrates

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Centrosome-dependent exit of cytokinesis in animal cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Centrosomes as command centres for cellular control

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Tetraploid state induces p53-dependent arrest of nontransformed mammalian cells in G1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

The centrosome and cellular organization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Mode of centriole duplication and distribution

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Centriole cycle in Chinese hamster ovary cells as determined by whole-mount electron microscopy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Centrioles in the cell cycle. I. Epithelial cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Dissociation of centrosome replication events from cycles of DNA synthesis and mitotic division in hydroxyurea-arrested Chinese hamster ovary cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Requirement of Cdk2-cyclin E activity for repeated centrosome reproduction in Xenopus egg extracts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Cyclin-dependent kinase control of centrosome duplication

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Cyclin-dependent kinase 2 (Cdk2) is required for centrosome duplication in mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Centrosome duplication in mammalian somatic cells requires E2F and Cdk2-cyclin A.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

A role for cyclin E/Cdk2 in the timing of the midblastula transition in Xenopus embryos

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Cyclin E controls S phase progression and its down-regulation during Drosophila embryogenesis is required for the arrest of cell proliferation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Protein synthesis and the cell cycle: centrosome reproduction in sea urchin eggs is not under translational control

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Nucleophosmin/B23 is a target of CDK2/cyclin E in centrosome duplication

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

The mouse Mps1p-like kinase regulates centrosome duplication

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

A centrosomal function for the human Nek2 protein kinase, a member of the NIMA family of cell cycle regulators.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

The centrosomal protein C-Nap1 is required for cell cycle-regulated centrosome cohesion

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Abnormal centrosome amplification in the absence of p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Direct regulation of the centrosome duplication cycle by the p53-p21Waf1/Cip1 pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Mitotic kinases as regulators of cell division and its checkpoints

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

The C. elegans zyg-1 gene encodes a regulator of centrosome duplication with distinct maternal and paternal roles in the embryo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Components of an SCF ubiquitin ligase localize to the centrosome and regulate the centrosome duplication cycle

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

The SCF ubiquitin ligase protein slimb regulates centrosome duplication in Drosophila.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Targeted disruption of Skp2 results in accumulation of cyclin E and p27(Kip1), polyploidy and centrosome overduplication

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Alzheimer presenilins in the nuclear membrane, interphase kinetochores, and centrosomes suggest a role in chromosome segregation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Centrosome disorganization in fibroblast cultures derived from R6/2 Huntington's disease (HD) transgenic mice and HD patients

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Centrosome proteins: a major class of autoantigens in scleroderma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Vaccinia virus infection disrupts microtubule organization and centrosome function.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Multiple centrosome formation induced by the expression of Vpr gene of human immunodeficiency virus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Anticentriolar autoantibodies in children with central nervous system manifestations of Mycoplasma pneumoniae infection

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Allelotype of colorectal carcinomas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Centrosome amplification as a possible mechanism for numerical chromosome aberrations in cerebral primitive neuroectodermal tumors with TP53 mutations

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Centrosome hypertrophy in human breast tumors: implications for genomic stability and cell polarity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Altered centrosome structure is associated with abnormal mitoses in human breast tumors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Centrosome abnormalities in human carcinomas of the gallbladder and intrahepatic and extrahepatic bile ducts.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Centrosome hyperamplification in head and neck squamous cell carcinoma: a potential phenotypic marker of tumor aggressiveness

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Microtubule nucleating capacity of centrosomes in tissue sections

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Centrosomes and cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Managing the centrosome numbers game: from chaos to stability in cancer cell division

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

The human papillomavirus type 16 E6 and E7 oncoproteins cooperate to induce mitotic defects and genomic instability by uncoupling centrosome duplication from the cell division cycle

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Formation of the tetraploid intermediate is associated with the development of cells with more than four centrioles in the elastase-simian virus 40 tumor antigen transgenic mouse model of pancreatic cancer.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Stepwise progression of centrosome defects associated with local tumor growth and metastatic process of human pancreatic carcinoma cells transplanted orthotopically into nude mice.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Centrosome amplification and instability occurs exclusively in aneuploid, but not in diploid colorectal cancer cell lines, and correlates with numerical chromosomal aberrations

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

The interphase microtubule damage checkpoint defines an S-phase commitment point and does not require p21(waf-1).

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

A role for cyclin D3 in the endomitotic cell cycle

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Asymmetrical segregation of chromosomes with a normal metaphase/anaphase checkpoint in polyploid megakaryocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Multi-step control of spindle pole body duplication by cyclin-dependent kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Deregulated cyclin E induces chromosome instability

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Synergistic induction of centrosome hyperamplification by loss of p53 and cyclin E overexpression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Centrosome abnormalities and genomic instability by episomal expression of human papillomavirus type 16 in raft cultures of human keratinocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Role of p21(Cip1/Waf1) in cell-cycle exit of endomitotic megakaryocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Centrosome hyperamplification in human cancer: chromosome instability induced by p53 mutation and/or Mdm2 overexpression.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Genomic convergence and suppression of centrosome hyperamplification in primary p53-/- cells in prolonged culture

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Centrosome amplification and a defective G2-M cell cycle checkpoint induce genetic instability in BRCA1 exon 11 isoform-deficient cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

BRCA1-associated tumorigenesis: what have we learned from knockout mice?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Mammalian recombination-repair genes XRCC2 and XRCC3 promote correct chromosome segregation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Structure and function of the centriole in animal cells: progress and questions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402454

7 January 2021

Identifiers

DOI

10.1038/SJ.LEU.2402454

1 reference

Dimensions Publication ID

3 August 2017

0 references

1 reference