(Q39658220)

English

Farnesyl transferase inhibitor treatment of breast cancer cells leads to altered RhoA and RhoC GTPase activity and induces a dormant phenotype

scientific article published on 26 October 2010

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

Farnesyl transferase inhibitor treatment of breast cancer cells leads to altered RhoA and RhoC GTPase activity and induces a dormant phenotype (English)

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

author name string

Moumita Chatterjee

1

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

Kenneth L van Golen

2

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

language of work or name

0 references

publication date

26 October 2010

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

number of pages

9

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based on heuristic

inferred from page(s)

International Journal of Cancer

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

129

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Europe PubMed Central

PubMed publication ID

13 September 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

61-69

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

Why three Rho proteins? RhoA, RhoB, RhoC, and cell motility

1 reference

https://api.crossref.org/works/10.1002%2FIJC.25655

21 January 2018

RhoC is dispensable for embryogenesis and tumor initiation but essential for metastasis

1 reference

https://api.crossref.org/works/10.1002%2FIJC.25655

21 January 2018

Integrin alpha5beta1 promotes survival of growth-arrested breast cancer cells: an in vitro paradigm for breast cancer dormancy in bone marrow

1 reference

https://api.crossref.org/works/10.1002%2FIJC.25655

21 January 2018

Dual FGF-2 and intergrin alpha5beta1 signaling mediate GRAF-induced RhoA inactivation in a model of breast cancer dormancy

1 reference

https://api.crossref.org/works/10.1002%2FIJC.25655

21 January 2018

Rho GTPases in PC-3 prostate cancer cell morphology, invasion and tumor cell diapedesis

1 reference

https://api.crossref.org/works/10.1002%2FIJC.25655

21 January 2018

Functional analysis of the contribution of RhoA and RhoC GTPases to invasive breast carcinoma

1 reference

https://api.crossref.org/works/10.1002%2FIJC.25655

21 January 2018

Multiple signaling pathways are activated during insulin-like growth factor-I (IGF-I) stimulated breast cancer cell migration

1 reference

https://api.crossref.org/works/10.1002%2FIJC.25655

21 January 2018

Oncogenic Ras downregulates Rac activity, which leads to increased Rho activity and epithelial-mesenchymal transition

1 reference

https://api.crossref.org/works/10.1002%2FIJC.25655

21 January 2018

Effect of a farnesyl transferase inhibitor (R115777) on ductal carcinoma in situ of the breast in a human xenograft model and on breast and ovarian cancer cell growth in vitro and in vivo.

1 reference

https://api.crossref.org/works/10.1002%2FIJC.25655

21 January 2018

Inhibition of metastatic outgrowth from single dormant tumor cells by targeting the cytoskeleton.

1 reference

https://api.crossref.org/works/10.1002%2FIJC.25655

21 January 2018

Anti-RhoA and anti-RhoC siRNAs inhibit the proliferation and invasiveness of MDA-MB-231 breast cancer cells in vitro and in vivo.

1 reference

https://api.crossref.org/works/10.1002%2FIJC.25655

21 January 2018

Roles of the Rac1 and Rac3 GTPases in human tumor cell invasion

1 reference

https://api.crossref.org/works/10.1002%2FIJC.25655

21 January 2018

Farnesyltransferase inhibitors: Ras research yields a potential cancer therapeutic

1 reference

https://api.crossref.org/works/10.1002%2FIJC.25655

21 January 2018

Evidence that farnesyltransferase inhibitors suppress Ras transformation by interfering with Rho activity

1 reference

https://api.crossref.org/works/10.1002%2FIJC.25655

21 January 2018

Cell growth inhibition by farnesyltransferase inhibitors is mediated by gain of geranylgeranylated RhoB.

1 reference

https://api.crossref.org/works/10.1002%2FIJC.25655

21 January 2018

Dormancy and breast cancer

1 reference

https://api.crossref.org/works/10.1002%2FIJC.25655

21 January 2018

Characterization of RhoC expression in benign and malignant breast disease: a potential new marker for small breast carcinomas with metastatic ability

1 reference

https://api.crossref.org/works/10.1002%2FIJC.25655

21 January 2018

Rho proteins induce metastatic properties in vivo

1 reference

https://api.crossref.org/works/10.1002%2FIJC.25655

21 January 2018

Rho GTPases are over-expressed in human tumors.

1 reference

https://api.crossref.org/works/10.1002%2FIJC.25655

21 January 2018

p190-B, a new member of the Rho GAP family, and Rho are induced to cluster after integrin cross-linking

1 reference

https://api.crossref.org/works/10.1002%2FIJC.25655

21 January 2018

The function of the p190 Rho GTPase-activating protein is controlled by its N-terminal GTP binding domain

1 reference

https://api.crossref.org/works/10.1002%2FIJC.25655

21 January 2018

A balance of signaling by Rho family small GTPases RhoA, Rac1 and Cdc42 coordinates cytoskeletal morphology but not cell survival

1 reference

https://api.crossref.org/works/10.1002%2FIJC.25655

21 January 2018

Signals from the Ras, Rac, and Rho GTPases converge on the Pak protein kinase in Rat-1 fibroblasts

1 reference

https://api.crossref.org/works/10.1002%2FIJC.25655

21 January 2018

Rho-regulatory proteins in breast cancer cell motility and invasion

1 reference

https://api.crossref.org/works/10.1002%2FIJC.25655

21 January 2018

Autophagy, senescence and tumor dormancy in cancer therapy

1 reference

https://api.crossref.org/works/10.1002%2FIJC.25655

21 January 2018

Extracellular matrix regulation of autophagy

1 reference

https://api.crossref.org/works/10.1002%2FIJC.25655

21 January 2018

Contributions of extracellular matrix signaling and tissue architecture to nuclear mechanisms and spatial organization of gene expression control

1 reference

https://api.crossref.org/works/10.1002%2FIJC.25655

21 January 2018

Regulation of pancreatic cancer cell migration and invasion by RhoC GTPase and caveolin-1

1 reference

https://api.crossref.org/works/10.1002%2FIJC.25655

21 January 2018

Fibronectin, integrins, and growth control

1 reference

https://api.crossref.org/works/10.1002%2FIJC.25655

21 January 2018

Evidence for the interplay between JNK and p53-DRAM signalling pathways in the regulation of autophagy

1 reference

https://api.crossref.org/works/10.1002%2FIJC.25655

21 January 2018

Extracellular matrix, Rac1 signaling, and estrogen-induced proliferation in MCF-7 breast cancer cells

1 reference

https://api.crossref.org/works/10.1002%2FIJC.25655

21 January 2018

The small GTP-binding protein rho activates c-Jun N-terminal kinases/stress-activated protein kinases in human kidney 293T cells. Evidence for a Pak-independent signaling pathway

1 reference

https://api.crossref.org/works/10.1002%2FIJC.25655

21 January 2018

RhoC GTPase is required for PC-3 prostate cancer cell invasion but not motility

1 reference

https://api.crossref.org/works/10.1002%2FIJC.25655

21 January 2018

Rac downregulates Rho activity: reciprocal balance between both GTPases determines cellular morphology and migratory behavior

1 reference

https://api.crossref.org/works/10.1002%2FIJC.25655

21 January 2018

Mitogen activated protein kinase pathway is involved in RhoC GTPase induced motility, invasion and angiogenesis in inflammatory breast cancer

1 reference

https://api.crossref.org/works/10.1002%2FIJC.25655

21 January 2018

Inflammatory breast cancer

1 reference

https://api.crossref.org/works/10.1002%2FIJC.25655

21 January 2018

Identifiers

10.1002/IJC.25655

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

ResearchGate publication ID

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