(Q39663853)

English

Inhibition of phosphatidylinositol 3-kinase promotes tumor cell resistance to chemotherapeutic agents via a mechanism involving delay in cell cycle progression

scientific article published on August 22, 2010

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scholarly article

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Europe PubMed Central

PubMed publication ID

13 September 2017

Inhibition of phosphatidylinositol 3-kinase promotes tumor cell resistance to chemotherapeutic agents via a mechanism involving delay in cell cycle progression (English)

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Europe PubMed Central

PubMed publication ID

13 September 2017

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inferred from title

phosphoinositide-3 kinase inhibitor

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20736003

22 June 2024

author name string

Richard Sullivan

2

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13 September 2017

Gail T. McDonald

1

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20736003

22 June 2024

Geneviève C. Paré

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20736003

22 June 2024

Charles H. Graham

4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20736003

22 June 2024

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22 August 2010

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13 September 2017

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https://api.elsevier.com/content/article/PII:S0014482710004015?httpAccept=text/xml

1 reference

10.1016/J.YEXCR.2010.08.007

https://api.crossref.org/works/10.1016/J.YEXCR.2010.08.007

22 June 2024

https://api.elsevier.com/content/article/PII:S0014482710004015?httpAccept=text/plain

1 reference

10.1016/J.YEXCR.2010.08.007

https://api.crossref.org/works/10.1016/J.YEXCR.2010.08.007

22 June 2024

Experimental Cell Research

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Europe PubMed Central

PubMed publication ID

13 September 2017

316

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Europe PubMed Central

PubMed publication ID

13 September 2017

19

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Europe PubMed Central

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13 September 2017

3197-3206

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

Cell signaling and cancer

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The PI3K inhibitor arsenal: choose your weapon!

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PI3K in lymphocyte development, differentiation and activation

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Cellular function of phosphoinositide 3-kinases: implications for development, homeostasis, and cancer.

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Phosphoinositide 3-OH kinase p85alpha and p110beta are essential for androgen receptor transactivation and tumor progression in prostate cancers

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Role of the phosphatidylinositol 3'-kinase-Akt signal pathway in the proliferation of human pancreatic ductal carcinoma cell lines

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Growth inhibition of human malignant glioma cells induced by the PI3-K-specific inhibitor

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Constitutive phosphoinositide 3-kinase/Akt activation represents a favorable prognostic factor in de novo acute myelogenous leukemia patients.

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Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

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A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V

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Synthesis and biological evaluation of 4-morpholino-2-phenylquinazolines and related derivatives as novel PI3 kinase p110alpha inhibitors

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Beyond PTEN mutations: the PI3K pathway as an integrator of multiple inputs during tumorigenesis

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Inhibition of phosphatidylinositol-3-kinase causes increased sensitivity to radiation through a PKB-dependent mechanism

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PTEN/MMAC1/TEP1 suppresses the tumorigenicity and induces G1 cell cycle arrest in human glioblastoma cells

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7 January 2021

Tangeretin sensitizes cisplatin-resistant human ovarian cancer cells through downregulation of phosphoinositide 3-kinase/Akt signaling pathway.

1 reference

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7 January 2021

Inhibition of PI3K/Akt partially leads to the inhibition of PrP(C)-induced drug resistance in gastric cancer cells

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The F-box protein Skp2 is a ubiquitylation target of a Cul1-based core ubiquitin ligase complex: evidence for a role of Cul1 in the suppression of Skp2 expression in quiescent fibroblasts

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Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

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Multiple roles of the PI3K/PKB (Akt) pathway in cell cycle progression

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Timeline: Chemotherapy and the war on cancer.

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Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27(Kip1) by PKB/Akt-mediated phosphorylation in breast cancer

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7 January 2021

Differential modulation of zinc-stimulated p21(Cip/WAF1) and cyclin D1 induction by inhibition of PI3 kinase in HT-29 colorectal cancer cells

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7 January 2021

The phosphatidylinositol 3-Kinase AKT pathway in human cancer

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Impact of the cyclin-dependent kinase inhibitor p27Kip1 on resistance of tumor cells to anticancer agents

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Targeting the PI3K/Akt/mTOR pathway: effective combinations and clinical considerations

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Phosphoinositide 3-kinase/Akt pathway plays an important role in chemoresistance of gastric cancer cells against etoposide and doxorubicin induced cell death

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Phosphatidylinositol 3-kinase inhibition by LY294002 radiosensitizes human cervical cancer cell lines

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Epidermal growth factor receptor-dependent Akt activation by oxidative stress enhances cell survival

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Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB.

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22 June 2024

Identifiers

10.1016/J.YEXCR.2010.08.007

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

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