(Q39663853)

English

Inhibition of phosphatidylinositol 3-kinase promotes tumor cell resistance to chemotherapeutic agents via a mechanism involving delay in cell cycle progression

scientific article published on 22 August 2010

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Europe PubMed Central

13 September 2017

Inhibition of phosphatidylinositol 3-kinase promotes tumor cell resistance to chemotherapeutic agents via a mechanism involving delay in cell cycle progression (English)

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Europe PubMed Central

13 September 2017

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Gail T McDonald

1

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Europe PubMed Central

13 September 2017

Richard Sullivan

2

1 reference

Europe PubMed Central

13 September 2017

Geneviève C Paré

3

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Europe PubMed Central

13 September 2017

Charles H Graham

4

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Europe PubMed Central

13 September 2017

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publication date

22 August 2010

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Europe PubMed Central

13 September 2017

Experimental Cell Research

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Europe PubMed Central

13 September 2017

316

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Europe PubMed Central

13 September 2017

19

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Europe PubMed Central

13 September 2017

3197-3206

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Europe PubMed Central

13 September 2017

Cell signaling and cancer

1 reference

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Role of the phosphatidylinositol 3'-kinase-Akt signal pathway in the proliferation of human pancreatic ductal carcinoma cell lines

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Inhibition of phosphatidylinositol-3-kinase causes increased sensitivity to radiation through a PKB-dependent mechanism

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Tangeretin sensitizes cisplatin-resistant human ovarian cancer cells through downregulation of phosphoinositide 3-kinase/Akt signaling pathway.

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The F-box protein Skp2 is a ubiquitylation target of a Cul1-based core ubiquitin ligase complex: evidence for a role of Cul1 in the suppression of Skp2 expression in quiescent fibroblasts

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Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

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Multiple roles of the PI3K/PKB (Akt) pathway in cell cycle progression

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Timeline: Chemotherapy and the war on cancer.

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Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27(Kip1) by PKB/Akt-mediated phosphorylation in breast cancer

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The phosphatidylinositol 3-Kinase AKT pathway in human cancer

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Impact of the cyclin-dependent kinase inhibitor p27Kip1 on resistance of tumor cells to anticancer agents

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Targeting the PI3K/Akt/mTOR pathway: effective combinations and clinical considerations

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Phosphoinositide 3-kinase/Akt pathway plays an important role in chemoresistance of gastric cancer cells against etoposide and doxorubicin induced cell death

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Phosphatidylinositol 3-kinase inhibition by LY294002 radiosensitizes human cervical cancer cell lines

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Epidermal growth factor receptor-dependent Akt activation by oxidative stress enhances cell survival

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Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB.

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Activation of the PI3K/Akt pathway and chemotherapeutic resistance

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Identifiers

10.1016/J.YEXCR.2010.08.007

1 reference

Europe PubMed Central

13 September 2017

1 reference

Europe PubMed Central

13 September 2017

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