(Q39664189)

13 September 2017

title

Actinomycin D decreases Mcl-1 expression and acts synergistically with ABT-737 against small cell lung cancer cell lines (English)

1 reference

13 September 2017

Actinomycin D Decreases Mcl-1 Expression and Acts Synergistically with ABT-737 against Small Cell Lung Cancer Cell Lines (English)

1 reference

https://api.crossref.org/works/10.1158/1078-0432.CCR-10-0640

21 June 2024

1 reference

1 reference

Haishan Xu

1

1 reference

13 September 2017

Geoffrey W. Krystal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20732961

21 June 2024

language of work or name

English

0 references

publication date

23 August 2010

1 reference

full work available at URL

13 September 2017

https://aacrjournals.org/clincancerres/article-pdf/16/17/4392/1991187/4392.pdf

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20732961

http://clincancerres.aacrjournals.org/cgi/content/abstract/16/17/4392

21 June 2024

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20732961

https://aacrjournals.org/clincancerres/article-pdf/16/17/4392/1991187/4392.pdf

21 June 2024

file format

Portable Document Format

1 reference

https://api.crossref.org/works/10.1158/1078-0432.CCR-10-0640

21 June 2024

published in

Clinical Cancer Research

1 reference

13 September 2017

volume

16

1 reference

13 September 2017

issue

17

1 reference

13 September 2017

page(s)

4392-4400

1 reference

13 September 2017

cites work

Small-cell lung cancer

1

1 reference

https://api.crossref.org/works/10.1158/1078-0432.CCR-10-0640

Apoptosis defects and chemotherapy resistance: molecular interaction maps and networks

21 June 2024

2

1 reference

https://api.crossref.org/works/10.1158/1078-0432.CCR-10-0640

Small cell carcinomas of the lung express the Bcl-2 protein

21 June 2024

3

1 reference

https://api.crossref.org/works/10.1158/1078-0432.CCR-10-0640

Influence of Bcl-2 family members on the cellular response of small-cell lung cancer cell lines to ABT-737.

21 June 2024

4

1 reference

https://api.crossref.org/works/10.1158/1078-0432.CCR-10-0640

Alterations in the Noxa/Mcl-1 axis determine sensitivity of small cell lung cancer to the BH3 mimetic ABT-737.

21 June 2024

5

1 reference

https://api.crossref.org/works/10.1158/1078-0432.CCR-10-0640

Mimicking the BH3 domain to kill cancer cells

21 June 2024

6

1 reference

https://api.crossref.org/works/10.1158/1078-0432.CCR-10-0640

An inhibitor of Bcl-2 family proteins induces regression of solid tumours

21 June 2024

7

1 reference

https://api.crossref.org/works/10.1158/1078-0432.CCR-10-0640

ABT-263: a potent and orally bioavailable Bcl-2 family inhibitor

21 June 2024

8

1 reference

https://api.crossref.org/works/10.1158/1078-0432.CCR-10-0640

Structural insights into the degradation of Mcl-1 induced by BH3 domains

21 June 2024

9

1 reference

https://api.crossref.org/works/10.1158/1078-0432.CCR-10-0640

Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins

21 June 2024

10

1 reference

https://api.crossref.org/works/10.1158/1078-0432.CCR-10-0640

Targeting multiple arms of the apoptotic regulatory machinery

21 June 2024

11

1 reference

https://api.crossref.org/works/10.1158/1078-0432.CCR-10-0640

Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia

21 June 2024

12

1 reference

https://api.crossref.org/works/10.1158/1078-0432.CCR-10-0640

Mcl-1 down-regulation potentiates ABT-737 lethality by cooperatively inducing Bak activation and Bax translocation

21 June 2024

13

1 reference

https://api.crossref.org/works/10.1158/1078-0432.CCR-10-0640

Pharmacokinetics of actinomycin 0 in patients with malignant melanoma

21 June 2024

14

1 reference

https://api.crossref.org/works/10.1158/1078-0432.CCR-10-0640

Messenger RNA in HeLa cells: Kinetics of formation and decay

21 June 2024

17

1 reference

https://api.crossref.org/works/10.1158/1078-0432.CCR-10-0640

Pharmacokinetics of dactinomycin in a pediatric patient population: a United Kingdom Children's Cancer Study Group Study

21 June 2024

18

1 reference

https://api.crossref.org/works/10.1158/1078-0432.CCR-10-0640

A simple, rapid technique for determination of the effects of chemotherapeutic agents on mammalian cell-cycle traverse

21 June 2024

21

1 reference

https://api.crossref.org/works/10.1158/1078-0432.CCR-10-0640

Concomitant inhibition of MDM2 and Bcl-2 protein function synergistically induce mitochondrial apoptosis in AML.

21 June 2024

23

1 reference

https://api.crossref.org/works/10.1158/1078-0432.CCR-10-0640

Activity of the Bcl-2 family inhibitor ABT-263 in a panel of small cell lung cancer xenograft models

21 June 2024

24

1 reference

https://api.crossref.org/works/10.1158/1078-0432.CCR-10-0640

Intensive combined chemotherapy and radiotherapy in patients with nonresectable bronchogenic carcinoma

21 June 2024

25

1 reference

https://api.crossref.org/works/10.1158/1078-0432.CCR-10-0640

Molecular genetics of small cell lung carcinoma

21 June 2024

26

1 reference

https://api.crossref.org/works/10.1158/1078-0432.CCR-10-0640

Specific activation of the p53 pathway by low dose actinomycin D: a new route to p53 based cyclotherapy.

21 June 2024

27

1 reference

https://api.crossref.org/works/10.1158/1078-0432.CCR-10-0640

21 June 2024

Identifiers

1 reference

13 September 2017

1 reference