(Q39675496)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20661222%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

title

MCPH1/BRIT1 limits ionizing radiation-induced centrosome amplification (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20661222%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20661222%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

James Brown

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20661222%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Emer Bourke

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20661222%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Peter Dockery

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20661222%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Ciaran G Morrison

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20661222%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

author name string

J A L Brown

1

1 reference

13 September 2017

E Bourke

2

1 reference

13 September 2017

P Dockery

4

1 reference

13 September 2017

C G Morrison

5

1 reference

13 September 2017

language of work or name

English

0 references

publication date

26 July 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20661222%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20661222%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

volume

29

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20661222%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

issue

40

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20661222%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

page(s)

5537-5544

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20661222%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/onc.2010.302

8 February 2020

exact match

0 references

cites work

Regulation of mitotic entry by microcephalin and its overlap with ATR signalling

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.302

DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.302

DNA damage induces Chk1-dependent threonine-160 phosphorylation and activation of Cdk2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.302

DNA damage induces Chk1-dependent centrosome amplification.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.302

Managing the centrosome numbers game: from chaos to stability in cancer cell division

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.302

Microcephalin coordinates mitosis in the syncytial Drosophila embryo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.302

Centrosome amplification and the development of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.302

Centrosome amplification induced by DNA damage occurs during a prolonged G2 phase and involves ATM.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.302

A mechanism linking extra centrosomes to chromosomal instability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.302

Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.302

Identification of microcephalin, a protein implicated in determining the size of the human brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.302

The DNA-damage response in human biology and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.302

Distinct BRCT domains in Mcph1/Brit1 mediate ionizing radiation-induced focus formation and centrosomal localization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.302

BRIT1/MCPH1 is essential for mitotic and meiotic recombination DNA repair and maintaining genomic stability in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.302

Multiple tumor suppressor pathways negatively regulate telomerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.302

BRIT1/MCPH1 is a DNA damage responsive protein that regulates the Brca1-Chk1 pathway, implicating checkpoint dysfunction in microcephaly

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.302

Structure meets function--centrosomes, genome maintenance and the DNA damage response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.302

Aurora-A overexpression reveals tetraploidization as a major route to centrosome amplification in p53-/- cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.302

Centrosome aberrations: cause or consequence of cancer progression?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.302

BRIT1/MCPH1 links chromatin remodelling to DNA damage response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.302

BRIT1 regulates early DNA damage response, chromosomal integrity, and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.302

Differential regulation of centrosome integrity by DNA damage response proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.302

The Drosophila homolog of MCPH1, a human microcephaly gene, is required for genomic stability in the early embryo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.302

Homologous recombination and non-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.302

Microcephalin and pericentrin regulate mitotic entry via centrosome-associated Chk1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.302

Mutations in microcephalin cause aberrant regulation of chromosome condensation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.302

Establishment of a mouse model with misregulated chromosome condensation due to defective Mcph1 function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.302

Cep76, a centrosomal protein that specifically restrains centriole reduplication

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.302

Microcephalin/MCPH1 associates with the Condensin II complex to function in homologous recombination repair.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.302

MCPH1 functions in an H2AX-dependent but MDC1-independent pathway in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.302

Microcephalin regulates BRCA2 and Rad51-associated DNA double-strand break repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.302

Microcephalin Is a DNA Damage Response Protein Involved in Regulation of CHK1 and BRCA1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.302