(Q39681333)

13 September 2017

MK-4827, a PARP-1/-2 inhibitor, strongly enhances response of human lung and breast cancer xenografts to radiation (English)

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13 September 2017

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8

Carlo Toniatti

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13 September 2017

3

K Kian Ang

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13 September 2017

Li Wang

1

1 reference

13 September 2017

Kathy A Mason

2

1 reference

13 September 2017

Thomas Buchholz

4

1 reference

13 September 2017

David Valdecanas

5

1 reference

13 September 2017

Anjili Mathur

6

1 reference

13 September 2017

Carolyn Buser-Doepner

7

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13 September 2017

Luka Milas

9

1 reference

13 September 2017

language of work or name

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30 November 2011

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Investigational New Drugs

13 September 2017

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13 September 2017

30

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13 September 2017

6

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13 September 2017

2113-2120

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https://scigraph.springernature.com/pub.10.1007/s10637-011-9770-x

13 September 2017

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cites work

Nicotinamide mononucleotide activation of a new DNA-dependent polyadenylic acid synthesizing nuclear enzyme

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9770-X

Poly(ADP-ribose) polymerase and the therapeutic effects of its inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9770-X

Poly(ADP-ribose): novel functions for an old molecule

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9770-X

PARP-1, PARP-2, and the cellular response to low doses of ionizing radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9770-X

Inhibition of poly(ADP-ribose) polymerase in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9770-X

Role of poly(ADP-ribose) formation in DNA repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9770-X

Poly(ADP-ribose) polymerase: a new therapeutic target?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9770-X

Poly(ADP-ribose) polymerase null mouse cells synthesize ADP-ribose polymers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9770-X

A review of PARP inhibitors: from bench to bedside

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9770-X

PARP inhibitors for cancer therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9770-X

PARP inhibitor development for systemic cancer targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9770-X

Radiosensitization of human and rodent cell lines by INO-1001, a novel inhibitor of poly(ADP-ribose) polymerase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9770-X

INO-1001, a novel inhibitor of poly(ADP-ribose) polymerase, enhances tumor response to doxorubicin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9770-X

PARP inhibitors: new partners in the therapy of cancer and inflammatory diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9770-X

Poly(ADP-ribose) polymerase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9770-X

Radiosensitization by the poly(ADP-ribose) polymerase inhibitor 4-amino-1,8-naphthalimide is specific of the S phase of the cell cycle and involves arrest of DNA synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9770-X

ABT-888, an orally active poly(ADP-ribose) polymerase inhibitor that potentiates DNA-damaging agents in preclinical tumor models

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9770-X

Anticancer chemosensitization and radiosensitization by the novel poly(ADP-ribose) polymerase-1 inhibitor AG14361.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9770-X

Enhanced radiosensitization of human glioma cells by combining inhibition of poly(ADP-ribose) polymerase with inhibition of heat shock protein 90

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9770-X

In vitro and in vivo radiosensitization of glioblastoma cells by the poly (ADP-ribose) polymerase inhibitor E7016.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9770-X

Inhibition of poly(ADP-ribose) polymerase enhances cell death and improves tumor growth delay in irradiated lung cancer models

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9770-X

Poly(ADP-ribose) polymerase inhibitor induces accelerated senescence in irradiated breast cancer cells and tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9770-X

Preclinical selection of a novel poly(ADP-ribose) polymerase inhibitor for clinical trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9770-X

Replication-dependent radiosensitization of human glioma cells by inhibition of poly(ADP-Ribose) polymerase: mechanisms and therapeutic potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9770-X

Discovery of 2-{4-[(3S)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide (MK-4827): a novel oral poly(ADP-ribose)polymerase (PARP) inhibitor efficacious in BRCA-1 and -2 mutant tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9770-X

Functional interaction between PARP-1 and PARP-2 in chromosome stability and embryonic development in mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9770-X

Pre-clinical and clinical evaluation of PARP inhibitors as tumour-specific radiosensitisers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9770-X

(ADP-ribose)n participates in DNA excision repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10637-011-9770-X

Head and neck cancer radiosensitization by the novel poly(ADP-ribose) polymerase inhibitor GPI-15427.

21 January 2018

1 reference

12 December 2020

Small-molecule PARP modulators--current status and future therapeutic potential.

1 reference

12 December 2020

PARP inhibitors in breast cancer.

1 reference

12 December 2020

Inhibition of poly(ADP)-ribose polymerase as a therapeutic strategy for breast cancer.

1 reference

12 December 2020

Clinical poly(ADP-ribose) polymerase inhibitors for the treatment of cancer.

1 reference

12 December 2020

Inhibition of nuclear NAD nucleosidase and poly ADP-ribose polymerase activity from rat liver by nicotinamide and 5'-methyl nicotinamide

1 reference

12 December 2020

10.1007/S10637-011-9770-X

Identifiers

DOI

1 reference

13 September 2017

1 reference