(Q39687424)

English

Sortilin facilitates signaling of ciliary neurotrophic factor and related helical type 1 cytokines targeting the gp130/leukemia inhibitory factor receptor beta heterodimer

scientific article published on 28 June 2010

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Sortilin facilitates signaling of ciliary neurotrophic factor and related helical type 1 cytokines targeting the gp130/leukemia inhibitory factor receptor beta heterodimer (English)

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

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Peder Madsen

4

1 reference

ORCID Public Data File 2021

author name string

Jakob Vejby Larsen

1

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Maria Hansen

2

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Bjarne Møller

3

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Jürgen Scheller

5

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Morten Nielsen

6

1 reference

Europe PubMed Central

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14 September 2017

Claus Munck Petersen

7

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

language of work or name

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publication date

28 June 2010

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Molecular and Cellular Biology

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Europe PubMed Central

PMC publication ID

14 September 2017

30

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

17

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

4175-4187

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2937557/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Ligands bind to Sortilin in the tunnel of a ten-bladed beta-propeller domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937557

14 September 2017

Conditional gp130 deficient mouse mutants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937557

14 September 2017

Phylogeny and evolution of class-I helical cytokines.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937557

14 September 2017

Neuropoietin, a new IL-6-related cytokine signaling through the ciliary neurotrophic factor receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937557

14 September 2017

Sortilin is essential for proNGF-induced neuronal cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937557

14 September 2017

Generation of the β-Amyloid Peptide and the Amyloid Precursor Protein C-terminal Fragment γ Are Potentiated by FE65L1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937557

14 September 2017

Principles of interleukin (IL)-6-type cytokine signalling and its regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937557

14 September 2017

Neurotensin receptor-1 and -3 complex modulates the cellular signaling of neurotensin in the HT29 cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937557

14 September 2017

The sortilin cytoplasmic tail conveys Golgi-endosome transport and binds the VHS domain of the GGA2 sorting protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937557

14 September 2017

Activation and functional characterization of the mosaic receptor SorLA/LR11.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937557

14 September 2017

Soluble gp130 is the natural inhibitor of soluble interleukin-6 receptor transsignaling responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937557

14 September 2017

CLF associates with CLC to form a functional heteromeric ligand for the CNTF receptor complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937557

14 September 2017

Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937557

14 September 2017

Identification and characterization of SorCS, a third member of a novel receptor family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937557

14 September 2017

Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937557

14 September 2017

Receptor recognition sites of cytokines are organized as exchangeable modules. Transfer of the leukemia inhibitory factor receptor-binding site from ciliary neurotrophic factor to interleukin-6.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937557

14 September 2017

Identification of a Leu-lle internalization motif within the cytoplasmic domain of the leukaemia inhibitory factor receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937557

14 September 2017

Propeptide cleavage conditions sortilin/neurotensin receptor-3 for ligand binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937557

14 September 2017

The 100-kDa neurotensin receptor is gp95/sortilin, a non-G-protein-coupled receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937557

14 September 2017

Apolipoprotein E binds to and potentiates the biological activity of ciliary neurotrophic factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937557

14 September 2017

Molecular identification of a novel candidate sorting receptor purified from human brain by receptor-associated protein affinity chromatography

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937557

14 September 2017

Molecular characterization of a novel human hybrid-type receptor that binds the alpha2-macroglobulin receptor-associated protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937557

14 September 2017

LIFR beta and gp130 as heterodimerizing signal transducers of the tripartite CNTF receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937557

14 September 2017

Proliferative responses and binding properties of hematopoietic cells transfected with low-affinity receptors for leukemia inhibitory factor, oncostatin M, and ciliary neurotrophic factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937557

14 September 2017

Crystal structure of dimeric human ciliary neurotrophic factor determined by MAD phasing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937557

14 September 2017

Mice lacking the CNTF receptor, unlike mice lacking CNTF, exhibit profound motor neuron deficits at birth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937557

14 September 2017

Three-dimensional structure of the LDL receptor-binding domain of human apolipoprotein E

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937557

14 September 2017

The receptor for ciliary neurotrophic factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937557

14 September 2017

Synthesis and localization of ciliary neurotrophic factor in the sciatic nerve of the adult rat after lesion and during regeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937557

14 September 2017

Sorting by the cytoplasmic domain of the amyloid precursor protein binding receptor SorLA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937557

14 September 2017

ProBDNF induces neuronal apoptosis via activation of a receptor complex of p75NTR and sortilin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937557

14 September 2017

Polarity and lipid raft association of the components of the ciliary neurotrophic factor receptor complex in Madin-Darby canine kidney cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937557

14 September 2017

The upper cytokine-binding module and the Ig-like domain of the leukaemia inhibitory factor (LIF) receptor are sufficient for a functional LIF receptor complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937557

25 September 2017

The box-1 region of the leukemia inhibitory factor receptor alpha-chain cytoplasmic domain is sufficient for hemopoietic cell proliferation and differentiation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937557

25 September 2017

The receptor-associated protein (RAP) binds calmodulin and is phosphorylated by calmodulin-dependent kinase II.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937557

25 September 2017

Ciliary neurotrophic factor enhances neuronal survival in embryonic rat hippocampal cultures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937557

15 June 2018

Cholinergic neuronotrophic factors: intraocular distribution of trophic activity for ciliary neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937557

15 June 2018

Roles for the pro-neurotrophin receptor sortilin in neuronal development, aging and brain injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937557

20 August 2018

Suckling defect in mice lacking the soluble haemopoietin receptor NR6.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937557

20 August 2018

Ciliary neurotrophic factor enhances the survival of Purkinje cells in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937557

20 August 2018

Control of embryonic motoneuron survival in vivo by ciliary neurotrophic factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/20584990

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of ciliary neurotrophic factor expression in myelin-related Schwann cells in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/20584990

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Released form of CNTF receptor alpha component as a soluble mediator of CNTF responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/20584990

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a region within the cytoplasmic domain of the interleukin-6 (IL-6) signal transducer gp130 important for ligand-induced endocytosis of the IL-6 receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/20584990

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neonatal death in mice lacking cardiotrophin-like cytokine is associated with multifocal neuronal hypoplasia

1 reference

https://pubmed.ncbi.nlm.nih.gov/20584990

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Localization of functional receptor epitopes on the structure of ciliary neurotrophic factor indicates a conserved, function-related epitope topography among helical cytokines

1 reference

https://pubmed.ncbi.nlm.nih.gov/20584990

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Changes in neurotrophic factor expression and receptor activation following exposure of hippocampal neuron/astrocyte cocultures to kainic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/20584990

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human CNTF and related cytokines: effects on DRG neurone survival

1 reference

https://pubmed.ncbi.nlm.nih.gov/20584990

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A bioactive designer cytokine for human hematopoietic progenitor cell expansion

1 reference

https://pubmed.ncbi.nlm.nih.gov/20584990

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.00274-10

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

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