(Q39702048)

English

Cyclooxygenase-2 inhibitor NS398 enhances radiosensitivity of radioresistant esophageal cancer cells by inhibiting AKT activation and inducing apoptosis

scientific article

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

Cyclooxygenase-2 inhibitor NS398 enhances radiosensitivity of radioresistant esophageal cancer cells by inhibiting AKT activation and inducing apoptosis (English)

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

apoptotic process

0 references

esophageal cancer

1 reference

based on heuristic

inferred from title

author name string

Shao-Min Che

1

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

Xiao-Zhi Zhang

2

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

Lei Hou

3

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

Tian-Bao Song

4

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

publication date

1 August 2010

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

Cancer Investigation

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

28

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

7

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

679-688

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

Multimodality treatment of esophageal cancer: a review of the current status and future directions

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

Differential gene expression profiles of radioresistant oesophageal cancer cell lines established by continuous fractionated irradiation

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

COX-2 inhibitors as radiation sensitizers for upper GI tract cancers: esophagus, stomach, and pancreas

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

Malignant transformation and antineoplastic actions of nonsteroidal antiinflammatory drugs (NSAIDs) on cyclooxygenase-null embryo fibroblasts

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

Overexpression of cyclooxygenase-2 is associated with radioresistance in oral squamous cell carcinoma

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

Significance of COX-2 expression in human esophageal squamous cell carcinoma

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

Prognostic role of cyclooxygenase-2 expression in esophageal carcinoma.

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

Overexpression of cyclooxygenase-2 is associated with chemoradiotherapy resistance and prognosis in esophageal squamous cell carcinoma patients

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

Expression of Cox-2 protein in radioresistant laryngeal cancer.

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

Mechanism of growth inhibitory effects of cyclooxygenase-2 inhibitor-NS398 on cancer cells

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

COX-2 mRNA expression in esophageal squamous cell carcinoma (ESCC) and effect by NSAID.

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

Anti-gastric cancer effects of celecoxib, a selective COX-2 inhibitor, through inhibition of Akt signaling

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

Celecoxib, a cyclooxygenase-2 inhibitor, induces apoptosis in human osteosarcoma cell line MG-63 via down-regulation of PI3K/Akt

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

3-phosphoinositide-dependent protein kinase-1/Akt signaling represents a major cyclooxygenase-2-independent target for celecoxib in prostate cancer cells

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

Celecoxib disrupts the canonical apoptotic network in HTLV-I cells through activation of Bax and inhibition of PKB/Akt

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

Radiosensitivity enhancement by celecoxib, a cyclooxygenase (COX)-2 selective inhibitor, via COX-2-dependent cell cycle regulation on human cancer cells expressing differential COX-2 levels

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

Cyclooxygenase-2 inhibitors demonstrate anti-proliferative effects in oesophageal cancer cells by prostaglandin E(2)-independent mechanisms

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

NS-398 induces apoptosis in human esophageal cancer cells through inhibition of NF-kappaB downstream regulation of cyclooxygenase-2.

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

Stress and radiation-induced activation of multiple intracellular signaling pathways

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt.

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

Targeting of AKT1 enhances radiation toxicity of human tumor cells by inhibiting DNA-PKcs-dependent DNA double-strand break repair.

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

Activation of the PI3-K/AKT pathway and implications for radioresistance mechanisms in head and neck cancer

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

Therapeutic potential of phosphoinositide 3-kinase inhibitors.

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

Combination of a COX-2 inhibitor with radiotherapy or radiochemotherapy in the treatment of thoracic cancer

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

Radiation sensitivity of human carcinoma cells transfected with small interfering RNA targeted against cyclooxygenase-2.

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

Combination of radiation and celebrex (celecoxib) reduce mammary and lung tumor growth

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

COX-2 inhibitors act as radiosensitizer in tumor treatment.

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

Mechanism and regulation of human non-homologous DNA end-joining

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

The role of double-strand break repair — insights from human genetics

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

The cyclooxygenase-2 inhibitor celecoxib induces apoptosis by blocking Akt activation in human prostate cancer cells independently of Bcl-2

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

Insulin-like growth factor-I inhibits transcriptional responses of transforming growth factor-beta by phosphatidylinositol 3-kinase/Akt-dependent suppression of the activation of Smad3 but not Smad2.

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

Synergy between celecoxib and radiotherapy results from inhibition of cyclooxygenase-2-derived prostaglandin E2, a survival factor for tumor and associated vasculature

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

Enhancement of glioblastoma radioresponse by a selective COX-2 inhibitor celecoxib: inhibition of tumor angiogenesis with extensive tumor necrosis

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

NSAIDs inhibit alpha V beta 3 integrin-mediated and Cdc42/Rac-dependent endothelial-cell spreading, migration and angiogenesis.

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

Inhibition of COX-2 with NS-398 decreases colon cancer cell motility through blocking epidermal growth factor receptor transactivation: possibilities for combination therapy.

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

Systematic review: Cyclo-oxygenase-2 in human oesophageal adenocarcinogenesis.

1 reference

https://api.crossref.org/works/10.3109%2F07357907.2010.483504

21 January 2018

Identifiers

10.3109/07357907.2010.483504

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

release_ow526q3hjvfb3iro5wr6qx7hhe

1 reference

https://api.fatcat.wiki/v0/release/ow526q3hjvfb3iro5wr6qx7hhe

24 November 2022

based on heuristic

mapped directly with Wikidata item

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q39702048&oldid=2088998950"