(Q39703256)

14 September 2017

title

A distinct role of RhoB in gastric cancer suppression (English)

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14 September 2017

Jitao Zhou

1

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14 September 2017

Yajie Zhu

2

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14 September 2017

Guoyun Zhang

3

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14 September 2017

Na Liu

4

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14 September 2017

Lijun Sun

5

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14 September 2017

Ming Liu

6

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14 September 2017

Meng Qiu

7

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14 September 2017

Deyun Luo

8

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14 September 2017

Qiulin Tang

9

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14 September 2017

Zhengyin Liao

10

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14 September 2017

Yi Zheng

11

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14 September 2017

Feng Bi

12

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14 September 2017

language of work or name

English

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publication date

1 March 2011

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International Journal of Cancer

14 September 2017

published in

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14 September 2017

volume

128

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14 September 2017

issue

5

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14 September 2017

page(s)

1057-1068

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14 September 2017

cites work

RHO-GTPases and cancer

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Searching new targets for anticancer drug design: the families of Ras and Rho GTPases and their effectors

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Ras and Rho GTPases: a family reunion

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Rho GTPases: signaling, migration, and invasion

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The role of RhoC in growth and metastatic capacity of melanoma

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Loss of RhoB expression in human lung cancer progression.

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RhoB is frequently downregulated in non-small-cell lung cancer and resides in the 2p24 homozygous deletion region of a lung cancer cell line

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1 reference

RhoB is dispensable for mouse development, but it modifies susceptibility to tumor formation as well as cell adhesion and growth factor signaling in transformed cells

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Rho GTPases in human breast tumours: expression and mutation analyses and correlation with clinical parameters

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Regulation of epidermal growth factor receptor traffic by the small GTPase rhoB

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RhoB is stabilized by transforming growth factor beta and antagonizes transcriptional activation

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Reversal of the malignant phenotype of gastric cancer cells by inhibition of RhoA expression and activity

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RhoC is essential for the metastasis of gastric cancer

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Oesophageal squamous cell neoplasia in head and neck cancer patients: upregulation of COX-2 during carcinogenesis

21 January 2018

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Frzb, a secreted Wnt antagonist, decreases growth and invasiveness of fibrosarcoma cells associated with inhibition of Met signaling

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15-Lipoxygenase-1 mediates cyclooxygenase-2 inhibitor-induced apoptosis in gastric cancer

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Interleukin 7 reduces the levels of spontaneous apoptosis in CD4+ and CD8+ T cells from HIV-1-infected individuals

21 January 2018

1 reference

Molecular basis for Rho GTPase signaling specificity

21 January 2018

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Cloning of the human RHOB gene promoter: characterization of a VNTR sequence that affects transcriptional activity

21 January 2018

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Histone deacetylase 1 represses the small GTPase RhoB expression in human nonsmall lung carcinoma cell line

21 January 2018

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Farnesyltransferase and geranylgeranyltransferase I inhibitors upregulate RhoB expression by HDAC1 dissociation, HAT association and histone acetylation of the RhoB promoter.

21 January 2018

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EGFR, ErbB2 and Ras but not Src suppress RhoB expression while ectopic expression of RhoB antagonizes oncogene-mediated transformation

21 January 2018

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RhoB controls Akt trafficking and stage-specific survival of endothelial cells during vascular development

21 January 2018

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Akt mediates Ras downregulation of RhoB, a suppressor of transformation, invasion, and metastasis

21 January 2018

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RhoB facilitates c-Myc turnover by supporting efficient nuclear accumulation of GSK-3.

21 January 2018

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21 January 2018

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Up-regulation of RhoB by glucocorticoids and its effects on the cell proliferation and NF-kappaB transcriptional activity

21 January 2018

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ROCK I-mediated activation of NF-kappaB by RhoB

21 January 2018

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Activation of RhoB by hypoxia controls hypoxia-inducible factor-1alpha stabilization through glycogen synthase kinase-3 in U87 glioblastoma cells

21 January 2018

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RhoB is required to mediate apoptosis in neoplastically transformed cells after DNA damage

21 January 2018

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RhoB alteration is necessary for apoptotic and antineoplastic responses to farnesyltransferase inhibitors

21 January 2018

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Cyclin B1 is a critical target of RhoB in the cell suicide program triggered by farnesyl transferase inhibition

21 January 2018

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The association between RhoB and caspase-2: changes with lovastatin-induced apoptosis

21 January 2018

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Farnesylated RhoB prevents cell cycle arrest and actin cytoskeleton disruption caused by the geranylgeranyltransferase I inhibitor GGTI-298.

21 January 2018

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The epidemiology of gastric cancer

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/IJC.25445

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14 September 2017

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