(Q39706243)

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The sulfated triphenyl methane derivative acid fuchsin is a potent inhibitor of amyloid formation by human islet amyloid polypeptide and protects against the toxic effects of amyloid formation

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Europe PubMed Central

PMC publication ID

14 September 2017

The sulfated triphenyl methane derivative acid fuchsin is a potent inhibitor of amyloid formation by human islet amyloid polypeptide and protects against the toxic effects of amyloid formation (English)

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

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inferred from title

Chris Middleton

object named as

Chris T Middleton

4

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Andisheh Abedini

object named as

Andisheh Abedini

2

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Daniel P Raleigh

object named as

Daniel P Raleigh

8

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Martin T. Zanni

6

object named as

Martin T Zanni

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

author name string

Fanling Meng

1

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Annette Plesner

3

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Europe PubMed Central

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14 September 2017

Kathryn J Potter

5

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Europe PubMed Central

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14 September 2017

C Bruce Verchere

7

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Europe PubMed Central

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14 September 2017

language of work or name

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publication date

7 May 2010

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Europe PubMed Central

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14 September 2017

Journal of Molecular Biology

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Europe PubMed Central

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14 September 2017

400

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Europe PubMed Central

PMC publication ID

14 September 2017

3

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

555-566

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Islet amyloid deposition limits the viability of human islet grafts but not porcine islet grafts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2902639

14 September 2017

2D IR provides evidence for mobile water molecules in beta-amyloid fibrils

1 reference

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14 September 2017

Two-dimensional IR spectroscopy and isotope labeling defines the pathway of amyloid formation with residue-specific resolution

1 reference

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14 September 2017

How to turn your pump-probe instrument into a multidimensional spectrometer: 2D IR and Vis spectroscopies via pulse shaping

1 reference

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14 September 2017

Molecular structural basis for polymorphism in Alzheimer's -amyloid fibrils

1 reference

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14 September 2017

Peptide and protein mimetics inhibiting amyloid beta-peptide aggregation.

1 reference

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Small molecule protein-protein interaction inhibitors as CNS therapeutic agents: current progress and future hurdles.

1 reference

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14 September 2017

Two-dimensional infrared spectra of isotopically diluted amyloid fibrils from Abeta40.

1 reference

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14 September 2017

Tracking fiber formation in human islet amyloid polypeptide with automated 2D-IR spectroscopy

1 reference

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14 September 2017

Small-molecule aggregates inhibit amyloid polymerization

1 reference

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Alzhemed: a potential treatment for Alzheimer's disease

1 reference

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14 September 2017

Automated 2D IR spectroscopy using a mid-IR pulse shaper and application of this technology to the human islet amyloid polypeptide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2902639

14 September 2017

Inhibition of amyloid fibril formation by polyphenols: structural similarity and aromatic interactions as a common inhibition mechanism

1 reference

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14 September 2017

Design of a mimic of nonamyloidogenic and bioactive human islet amyloid polypeptide (IAPP) as nanomolar affinity inhibitor of IAPP cytotoxic fibrillogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2902639

14 September 2017

Cell biology of protein misfolding: the examples of Alzheimer's and Parkinson's diseases

1 reference

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14 September 2017

Islet amyloid: a critical entity in the pathogenesis of type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2902639

14 September 2017

Islet amyloid polypeptide and type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2902639

14 September 2017

Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2902639

14 September 2017

The prohormone convertase enzyme 2 (PC2) is essential for processing pro-islet amyloid polypeptide at the NH2-terminal cleavage site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2902639

14 September 2017

Islet amyloid: a long-recognized but underappreciated pathological feature of type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2902639

14 September 2017

Sulfate content and specific glycosaminoglycan backbone of perlecan are critical for perlecan's enhancement of islet amyloid polypeptide (amylin) fibril formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2902639

14 September 2017

Defective prohormone processing and altered pancreatic islet morphology in mice lacking active SPC2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2902639

14 September 2017

Pancreatic islet cell toxicity of amylin associated with type-2 diabetes mellitus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2902639

14 September 2017

A novel peptide in the calcitonin gene related peptide family as an amyloid fibril protein in the endocrine pancreas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2902639

14 September 2017

Purification and characterization of a peptide from amyloid-rich pancreases of type 2 diabetic patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2902639

14 September 2017

Amyloid fibrils in human insulinoma and islets of Langerhans of the diabetic cat are derived from a neuropeptide-like protein also present in normal islet cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2902639

14 September 2017

The insulin secretory granule

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2902639

14 September 2017

Islet amyloid polypeptide. A new beta cell secretory product related to islet amyloid deposits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2902639

14 September 2017

Exploiting cross-amyloid interactions to inhibit protein aggregation but not function: nanomolar affinity inhibition of insulin aggregation by an IAPP mimic

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2902639

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Eprodisate for the treatment of renal disease in AA amyloidosis.

1 reference

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14 September 2017

Inhibition of islet amyloid polypeptide fibril formation: a potential role for heteroaromatic interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2902639

14 September 2017

Amylin compared with calcitonin gene-related peptide: structure, biology, and relevance to metabolic disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2902639

14 September 2017

Immunohistology of islet amyloid polypeptide in diabetes mellitus: semi-quantitative studies in a post-mortem series

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2902639

25 September 2017

Strategies for extracting structural information from 2D IR spectroscopy of amyloid: application to islet amyloid polypeptide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2902639

17 June 2018

Amyloid formation results in recurrence of hyperglycaemia following transplantation of human IAPP transgenic mouse islets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2902639

17 June 2018

Islet amyloid, increased A-cells, reduced B-cells and exocrine fibrosis: quantitative changes in the pancreas in type 2 diabetes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2902639

17 June 2018

Generation and characterization of phase and amplitude shaped femtosecond mid-IR pulses.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2902639

20 August 2018

Two-dimensional infrared spectroscopy provides evidence of an intermediate in the membrane-catalyzed assembly of diabetic amyloid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2902639

20 August 2018

Islets in type 2 diabetes: in honor of Dr. Robert C. Turner

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2902639

20 August 2018

Small-molecule inhibitors of islet amyloid polypeptide fibril formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2902639

20 August 2018

Rifampicin does not prevent amyloid fibril formation by human islet amyloid polypeptide but does inhibit fibril thioflavin-T interactions: implications for mechanistic studies of beta-cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2902639

20 August 2018

Targeting soluble Abeta peptide with Tramiprosate for the treatment of brain amyloidosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2902639

20 August 2018

Recovery and purification of highly aggregation-prone disulfide-containing peptides: application to islet amyloid polypeptide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2902639

20 August 2018

The role of His-18 in amyloid formation by human islet amyloid polypeptide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2902639

20 August 2018

Formation of amyloid in human pancreatic islets transplanted to the liver and spleen of nude mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2902639

20 August 2018

Seeding specificity in amyloid growth induced by heterologous fibrils

1 reference

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20 August 2018

Identification of a novel human islet amyloid polypeptide beta-sheet domain and factors influencing fibrillogenesis

1 reference

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20 August 2018

Developmental expression of the prohormone convertases PC1 and PC2 in mouse pancreatic islets.

1 reference

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20 August 2018

Arresting amyloidosis in vivo using small-molecule anionic sulphonates or sulphates: implications for Alzheimer's disease

1 reference

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20 August 2018

Widespread amyloid deposition in transplanted human pancreatic islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/20452363

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Advances in the treatment of amyloidosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20452363

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Incorporation of Pseudoproline Derivatives Allows the Facile Synthesis of Human IAPP, a Highly Amyloidogenic and Aggregation-Prone Polypeptide

1 reference

https://pubmed.ncbi.nlm.nih.gov/20452363

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Islet amyloid formed from diabetes-associated peptide may be pathogenic in type-2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20452363

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heparin-binding properties of the amyloidogenic peptides Abeta and amylin. Dependence on aggregation state and inhibition by Congo red

1 reference

https://pubmed.ncbi.nlm.nih.gov/20452363

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/20452363

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Femtosecond pulse shaping directly in the mid-IR using acousto-optic modulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20452363

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A Single-Point Mutation Converts the Highly Amyloidogenic Human Islet Amyloid Polypeptide into a Potent Fibrillization Inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/20452363

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of beta-cell prohormone convertase (PC)1/3 in processing of pro-islet amyloid polypeptide

1 reference

https://pubmed.ncbi.nlm.nih.gov/20452363

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.JMB.2010.05.001

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

ResearchGate publication ID

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