(Q39707182)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20445350%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

title

A recombinant immunotoxin targeting CD22 with low immunogenicity, low nonspecific toxicity, and high antitumor activity in mice (English)

1 reference

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1 February 2020

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20445350%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

5

Masanori Onda

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20445350%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

6

Ira Pastan

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20445350%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

author name string

Johanna K Hansen

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20445350%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

Laiman Xiang

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20445350%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

Richard Beers

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20445350%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

publication date

1 April 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20445350%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

published in

Journal of Immunotherapy

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20445350%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

volume

33

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20445350%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20445350%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

page(s)

297-304

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20445350%20AND%20SRC:MED&resulttype=core&format=json

HA22 (R490A) is a recombinant immunotoxin with increased antitumor activity without an increase in animal toxicity.

1 February 2020

cites work

1 reference

12 December 2020

Cleavage of pseudomonas exotoxin and diphtheria toxin by a furin-like enzyme prepared from beef liver

1 reference

12 December 2020

Structure of exotoxin A of Pseudomonas aeruginosa at 3.0-Angstrom resolution

1 reference

12 December 2020

Inhibition of TNF-alpha produced by Kupffer cells protects against the nonspecific liver toxicity of immunotoxin anti-Tac(Fv)-PE38, LMB-2

1 reference

12 December 2020

Processing of Pseudomonas exotoxin by a cellular protease results in the generation of a 37,000-Da toxin fragment that is translocated to the cytosol

1 reference

12 December 2020

An immunotoxin with greatly reduced immunogenicity by identification and removal of B cell epitopes

1 reference

12 December 2020

A protease-resistant immunotoxin against CD22 with greatly increased activity against CLL and diminished animal toxicity.

1 reference

12 December 2020

Furin-mediated cleavage of Pseudomonas exotoxin-derived chimeric toxins.

1 reference

12 December 2020

Recombinant RFB4 single-chain immunotoxin that is cytotoxic towards CD22-positive cells

1 reference

12 December 2020

Renal filtration, transport, and metabolism of low-molecular-weight proteins: A review

1 reference

12 December 2020

Recombinant immunotoxins in the treatment of cancer

1 reference

12 December 2020

High shed antigen levels within tumors: an additional barrier to immunoconjugate therapy

1 reference

12 December 2020

Efficacy of the anti-CD22 recombinant immunotoxin BL22 in chemotherapy-resistant hairy-cell leukemia

1 reference

12 December 2020

Phase I study of SS1P, a recombinant anti-mesothelin immunotoxin given as a bolus I.V. infusion to patients with mesothelin-expressing mesothelioma, ovarian, and pancreatic cancers

1 reference

12 December 2020

Characterization of the B cell epitopes associated with a truncated form of Pseudomonas exotoxin (PE38) used to make immunotoxins for the treatment of cancer patients

1 reference

12 December 2020

Immunotoxin treatment of cancer

1 reference

12 December 2020

Immunotoxin therapy of cancer

1 reference

12 December 2020

Protein transport in mouse kidney utilizing tyrosinase as an ultrastructural tracer

1 reference

12 December 2020

Phase I trial of recombinant immunotoxin RFB4(dsFv)-PE38 (BL22) in patients with B-cell malignancies

1 reference

12 December 2020

Immunotoxin and Taxol synergy results from a decrease in shed mesothelin levels in the extracellular space of tumors

1 reference

12 December 2020

Induction of optimal mucosal antibody responses: effects of age, immunization route(s), and dosing schedule in rats

1 reference

12 December 2020