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Ancient adaptive evolution of tetherin shaped the functions of Vpu and Nef in human immunodeficiency virus and primate lentiviruses.
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Europe PubMed Central
PMC publication ID
2898239
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20444900%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
title
Ancient adaptive evolution of tetherin shaped the functions of Vpu and Nef in human immunodeficiency virus and primate lentiviruses
(English)
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stated in
Europe PubMed Central
PMC publication ID
2898239
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20444900%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
main subject
virology
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adaptive evolution
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author
Harmit Singh Malik
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2
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Europe PubMed Central
PMC publication ID
2898239
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20444900%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
Efrem S. Lim
series ordinal
1
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Europe PubMed Central
PMC publication ID
2898239
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20444900%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
Michael Emerman
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3
object named as
Michael Emerman
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Europe PubMed Central
PMC publication ID
2898239
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20444900%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
language of work or name
English
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publication date
5 May 2010
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Europe PubMed Central
PMC publication ID
2898239
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20444900%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
published in
Journal of Virology
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Europe PubMed Central
PMC publication ID
2898239
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20444900%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
volume
84
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Europe PubMed Central
PMC publication ID
2898239
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20444900%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
issue
14
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Europe PubMed Central
PMC publication ID
2898239
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20444900%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
page(s)
7124-7134
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Europe PubMed Central
PMC publication ID
2898239
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20444900%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
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Antiviral activity of the interferon-induced cellular protein BST-2/tetherin
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Tetherin-driven adaptation of Vpu and Nef function and the evolution of pandemic and nonpandemic HIV-1 strains.
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Tetherin inhibits HIV-1 release by directly tethering virions to cells
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HIV-1 Vpu neutralizes the antiviral factor Tetherin/BST-2 by binding it and directing its beta-TrCP2-dependent degradation
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Vpu directs the degradation of the human immunodeficiency virus restriction factor BST-2/Tetherin via a {beta}TrCP-dependent mechanism
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Species-specific activity of SIV Nef and HIV-1 Vpu in overcoming restriction by tetherin/BST2
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The human immunodeficiency virus (HIV) type 2 envelope protein is a functional complement to HIV type 1 Vpu that enhances particle release of heterologous retroviruses.
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14 September 2017
The two biological activities of human immunodeficiency virus type 1 Vpu protein involve two separable structural domains.
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14 September 2017
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14 September 2017
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14 September 2017
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14 September 2017
HIV-1 Nef interferes with host cell motility by deregulation of Cofilin
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14 September 2017
HIV-1 antagonism of CD317 is species specific and involves Vpu-mediated proteasomal degradation of the restriction factor
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14 September 2017
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Identifiers
DOI
10.1128/JVI.00468-10
1 reference
stated in
Europe PubMed Central
PMC publication ID
2898239
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20444900%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
PMC publication ID
2898239
1 reference
stated in
Europe PubMed Central
PMC publication ID
2898239
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20444900%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
PubMed publication ID
20444900
1 reference
stated in
Europe PubMed Central
PMC publication ID
2898239
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20444900%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
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