(Q39715536)

English

Hepatitis B virus X protein promotes liver cell proliferation via a positive cascade loop involving arachidonic acid metabolism and p-ERK1/2.

scientific article published on 13 April 2010

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scholarly article

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Europe PubMed Central

PubMed publication ID

14 September 2017

Hepatitis B virus X protein promotes liver cell proliferation via a positive cascade loop involving arachidonic acid metabolism and p-ERK1/2. (English)

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

Hepatitis B virus

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author name string

Changliang Shan

1

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

Fuqing Xu

2

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Europe PubMed Central

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14 September 2017

Shuai Zhang

3

1 reference

Europe PubMed Central

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14 September 2017

Jiacong You

4

1 reference

Europe PubMed Central

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14 September 2017

Xiaona You

5

1 reference

Europe PubMed Central

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14 September 2017

Liyan Qiu

6

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14 September 2017

Jie Zheng

7

1 reference

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14 September 2017

Lihong Ye

8

1 reference

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14 September 2017

Xiaodong Zhang

9

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14 September 2017

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13 April 2010

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Europe PubMed Central

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14 September 2017

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Europe PubMed Central

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14 September 2017

20

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PubMed publication ID

14 September 2017

5

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14 September 2017

563-575

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Europe PubMed Central

PubMed publication ID

14 September 2017

https://scigraph.springernature.com/pub.10.1038/cr.2010.49

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The hepatitis B virus-X protein activates a phosphatidylinositol 3-kinase-dependent survival signaling cascade

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Transcriptional repression of the human p53 gene by hepatitis B viral X protein

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Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactions

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Akt activation by arachidonic acid metabolism occurs via oxidation and inactivation of PTEN tumor suppressor.

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Expression of HBx and COX-2 in chronic hepatitis B, cirrhosis and hepatocellular carcinoma: implication of HBx in upregulation of COX-2.

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Gene expression profiles of human liver cells mediated by hepatitis B virus X protein

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Transformation of human liver L-O2 cells mediated by stable HBx transfection

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Proliferation and migration mediated by Dkk-1/Wnt/beta-catenin cascade in a model of hepatocellular carcinoma cells

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Mitogen-activated protein kinases: new signaling pathways functioning in cellular responses to environmental stress

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Activation of PKCbeta(II) and PKCtheta is essential for LDL-induced cell proliferation of human aortic smooth muscle cells via Gi-mediated Erk1/2 activation and Egr-1 upregulation.

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Sphingosine-1-phosphate modulates both lipolysis and leptin production in differentiated rat white adipocytes

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Human hepatitis B virus X protein promotes cell proliferation and inhibits cell apoptosis through interacting with a serine protease Hepsin

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Premature cell cycle entry induced by hepatitis B virus regulatory HBx protein during compensatory liver regeneration

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Paracrine in vivo inhibitory effects of hepatitis B virus X protein (HBx) on liver cell proliferation: an alternative mechanism of HBx-related pathogenesis

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Hepatitis B virus X protein induces apoptosis in hepatoma cells through inhibiting Bcl-xL expression

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Leukotactin-1-induced ERK activation is mediated via Gi/Go protein/PLC/PKC delta/Ras cascades in HOS cells

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Regulation of tumor cell motility by ERK mitogen-activated protein kinases

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Hepatitis B virus X protein upregulates survivin expression in hepatoma tissues.

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The extracellular signal-regulated kinase: multiple substrates regulate diverse cellular functions

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p38 and ERK1/2 coordinate cellular migration and proliferation in epithelial wound healing: evidence of cross-talk activation between MAP kinase cascades

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A role for cyclooxygenase-2 inhibitors in the prevention and treatment of cancer.

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Potent cell growth inhibitory effects in hepatitis B virus X protein positive hepatocellular carcinoma cells by the selective cyclooxygenase-2 inhibitor celecoxib

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Identification of a natural mutant of HBV X protein truncated 27 amino acids at the COOH terminal and its effect on liver cell proliferation

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Identifiers

10.1038/CR.2010.49

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

14 September 2017

ResearchGate publication ID

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