(Q53564939)

15 May 2018

title

Akt activation by arachidonic acid metabolism occurs via oxidation and inactivation of PTEN tumor suppressor. (English)

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15 May 2018

author name string

T M Covey

series ordinal

1

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15 May 2018

K Edes

series ordinal

2

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15 May 2018

F A Fitzpatrick

series ordinal

3

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15 May 2018

language of work or name

English

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publication date

19 March 2007

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15 May 2018

published in

Oncogene

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15 May 2018

volume

26

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15 May 2018

issue

39

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15 May 2018

page(s)

5784-5792

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15 May 2018

Regulation of Akt by arachidonic acid and phosphoinositide 3-kinase in angiotensin II-stimulated vascular smooth muscle cells

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210391

Inflammation and cancer: how hot is the link?

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7 January 2021

The PI 3-kinase/Akt signaling pathway is activated due to aberrant Pten expression and targets transcription factors NF-kappaB and c-Myc in pancreatic cancer cells

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210391

7 January 2021

Regulation of FAK Ser-722 phosphorylation and kinase activity by GSK3 and PP1 during cell spreading and migration

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7 January 2021

Dysregulation of HIF and VEGF is a unifying feature of the familial hamartoma syndromes

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7 January 2021

New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway

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7 January 2021

AKT/PKB and other D3 phosphoinositide-regulated kinases: kinase activation by phosphoinositide-dependent phosphorylation

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7 January 2021

Redox regulation of PTEN and protein tyrosine phosphatases in H(2)O(2) mediated cell signaling

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7 January 2021

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

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7 January 2021

Cyclooxygenases and lipoxygenases as potential targets for treatment of pancreatic cancer

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7 January 2021

PI3K/Akt signalling pathway and cancer.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210391

7 January 2021

Regulation of the PTEN phosphatase

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210391

7 January 2021

Nonsteroidal anti-inflammatory drugs, short-chain fatty acids, and reactive oxygen metabolism in human colorectal cancer cells

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7 January 2021

Angiotensin II activates Akt/protein kinase B by an arachidonic acid/redox-dependent pathway and independent of phosphoinositide 3-kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210391

7 January 2021

Activation of the phosphatidylinositol 3-kinase-Akt/protein kinase B signaling pathway in arachidonic acid-stimulated human myeloid and endothelial cells: involvement of the ErbB receptor family

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210391

7 January 2021

Arachidonic acid activates phosphatidylinositol 3-kinase signaling and induces gene expression in prostate cancer

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210391

7 January 2021

Akt/PKB promotes cancer cell invasion via increased motility and metalloproteinase production

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210391

7 January 2021

Haploinsufficiency of the Pten tumor suppressor gene promotes prostate cancer progression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210391

7 January 2021

Reversible oxidation and inactivation of the tumor suppressor PTEN in cells stimulated with peptide growth factors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210391

7 January 2021

Reversible inactivation of the tumor suppressor PTEN by H2O2

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210391

7 January 2021

PTEN: The down side of PI 3-kinase signalling.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210391

7 January 2021

Redox regulation of PI 3-kinase signalling via inactivation of PTEN

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210391

7 January 2021

Angiotensin II-induced Akt activation is mediated by metabolites of arachidonic acid generated by CaMKII-stimulated Ca2(+)-dependent phospholipase A2.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210391

7 January 2021

A causal relationship between unscheduled eicosanoid signaling and tumor development: cancer chemoprevention by inhibitors of arachidonic acid metabolism

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7 January 2021

Recent advances on the molecular mechanisms involved in pancreatic cancer progression and therapies

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7 January 2021

The major target of the endogenously generated reactive oxygen species in response to insulin stimulation is phosphatase and tensin homolog and not phosphoinositide-3 kinase (PI-3 kinase) in the PI-3 kinase/Akt pathway

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210391

7 January 2021

Pten constrains centroacinar cell expansion and malignant transformation in the pancreas

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210391

7 January 2021

Redox redux: revisiting PTPs and the control of cell signaling

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210391

7 January 2021

Pten dose dictates cancer progression in the prostate

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210391

7 January 2021

Reactive lipid species from cyclooxygenase-2 inactivate tumor suppressor LKB1/STK11: cyclopentenone prostaglandins and 4-hydroxy-2-nonenal covalently modify and inhibit the AMP-kinase kinase that modulates cellular energy homeostasis and protein tra

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210391

7 January 2021

Translation initiation and its deregulation during tumorigenesis

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210391

7 January 2021

Elevation of serum group II phospholipase A2 levels in patients with advanced cancer

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210391

7 January 2021

Redox regulation of PTEN by S-nitrosothiols

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210391

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1210391

1 reference

15 May 2018

1 reference

15 May 2018