(Q39725912)

14 September 2017

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title

Recent developments in the hammerhead ribozyme field (English)

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14 September 2017

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Vaish NK

1

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14 September 2017

Kore AR

series ordinal

2

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14 September 2017

Eckstein F

series ordinal

3

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14 September 2017

language of work or name

English

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publication date

1 December 1998

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14 September 2017

Nucleic Acids Research

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14 September 2017

26

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14 September 2017

23

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14 September 2017

5237-5242

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The structure, function and application of the hammerhead ribozyme

14 September 2017

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2F26.23.5237

Sequence requirements of the hammerhead RNA self-cleavage reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2F26.23.5237

A kinetic and thermodynamic analysis of cleavage site mutations in the hammerhead ribozyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2F26.23.5237

Structural variation induced by different nucleotides at the cleavage site of the hammerhead ribozyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2F26.23.5237

Sequence specificity of the hammerhead ribozyme revisited; the NHH rule

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2F26.23.5237

Extending the cleavage rules for the hammerhead ribozyme: mutating adenosine15.1 to inosine15.1 changes the cleavage site specificity from N16.2U16.1H17 to N16.2C16.1H17.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2F26.23.5237

The crystal structure of an all-RNA hammerhead ribozyme: a proposed mechanism for RNA catalytic cleavage

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2F26.23.5237

In vitro selection of a purine nucleotide-specific hammerheadlike ribozyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2F26.23.5237

Ribozymes: structure and mechanism in RNA catalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2F26.23.5237

Capturing the structure of a catalytic RNA intermediate: the hammerhead ribozyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2F26.23.5237

Ion-induced folding of the hammerhead ribozyme: a fluorescence resonance energy transfer study

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2F26.23.5237

The structural basis of hammerhead ribozyme self-cleavage

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2F26.23.5237

Inhibition of the hammerhead ribozyme cleavage reaction by site-specific binding of Tb

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2F26.23.5237

Involvement of a specific metal ion in the transition of the hammerhead ribozyme to its catalytic conformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2F26.23.5237

Thiophosphate interference experiments locate phosphates important for the hammerhead RNA self-cleavage reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2F26.23.5237

Explanation by the double-metal-ion mechanism of catalysis for the differential metal ion effects on the cleavage rates of 5'-oxy and 5'-thio substrates by a hammerhead ribozyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2F26.23.5237

Evidence for a hydroxide ion bridging two magnesium ions at the active site of the hammerhead ribozyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2F26.23.5237

A two-metal ion mechanism operates in the hammerhead ribozyme-mediated cleavage of an RNA substrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2F26.23.5237

Metal ions play a passive role in the hairpin ribozyme catalysed reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2F26.23.5237

Therapeutic ribozymes: principles and applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2F26.23.5237

Selecting effective antisense reagents on combinatorial oligonucleotide arrays

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2F26.23.5237

Selection of efficient cleavage sites in target RNAs by using a ribozyme expression library

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2F26.23.5237

Correlation of activity with stability of chemically modified ribozymes in nuclei suspension

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2F26.23.5237

Nuclease-resistant ribozymes decrease stromelysin mRNA levels in rabbit synovium following exogenous delivery to the knee joint

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2F26.23.5237

Inhibition of Plasmodium falciparum proliferation in vitro by ribozymes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2F26.23.5237

A good antisense molecule is hard to find

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2F26.23.5237

Optimizing the cell efficacy of synthetic ribozymes. Site selection and chemical modifications of ribozymes targeting the proto-oncogene c-myb.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2F26.23.5237

A nuclease-resistant protein kinase C alpha ribozyme blocks glioma cell growth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2F26.23.5237

Mechanism of oligonucleotide release from cationic liposomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2F26.23.5237

Engineering liposomes for drug delivery: progress and problems

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2F26.23.5237

Toxicity of cationic lipid-ribozyme complexes in human prostate tumor cells can mimic ribozyme activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2F26.23.5237

Intracellular application of hairpin ribozyme genes against hepatitis B virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2F26.23.5237

Growth arrest of Epstein-Barr virus immortalized B lymphocytes by adenovirus-delivered ribozymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2F26.23.5237

Stable in vivo gene transduction via a novel adenoviral/retroviral chimeric vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2F26.23.5237

Expression of small, therapeutic RNAs in human cell nuclei.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2F26.23.5237

Distinct roles of the co-activators p300 and CBP in retinoic-acid-induced F9-cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2F26.23.5237

Efficient and specific ribozyme-mediated reduction of bovine alpha-lactalbumin expression in double transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2F26.23.5237

A ribozyme-mediated, gene "knockdown" strategy for the identification of gene function in zebrafish

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2F26.23.5237

Ribozyme-mediated high resistance against potato spindle tuber viroid in transgenic potatoes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2F26.23.5237

A ribozyme gene and an antisense gene are equally effective in conferring resistance to tobacco mosaic virus on transgenic tobacco

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2F26.23.5237

21 January 2018

Identifiers

DOI

10.1093/NAR/26.23.5237

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14 September 2017

1 reference

14 September 2017

1 reference