(Q39748955)

14 September 2017

1 reference

title

Innate signaling by mycobacterial cell wall components and relevance for development of adjuvants for subunit vaccines (English)

1 reference

14 September 2017

1 reference

2

1 reference

14 September 2017

Hermann Giresse Tima

1

1 reference

PubMed ID

27206681

14 September 2017

Marta Romano

series ordinal

3

1 reference

PubMed ID

27206681

14 September 2017

language of work or name

1 reference

20 May 2016

1 reference

Expert Review of Vaccines

14 September 2017

1 reference

14 September 2017

15

1 reference

14 September 2017

11

1 reference

14 September 2017

1409-1420

1 reference

Active and passive immunity, vaccine types, excipients and licensing

14 September 2017

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

Mechanism of action of licensed vaccine adjuvants

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

Alum interaction with dendritic cell membrane lipids is essential for its adjuvanticity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

The mechanism of action of MF59 - an innately attractive adjuvant formulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

Inflammasome-independent role of the apoptosis-associated speck-like protein containing CARD (ASC) in the adjuvant effect of MF59.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

Enhanced humoral and memory B cellular immunity using HPV16/18 L1 VLP vaccine formulated with the MPL/aluminium salt combination (AS04) compared to aluminium salt only

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

Adjuvant System AS03 containing α-tocopherol modulates innate immune response and leads to improved adaptive immunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

Influenza virosomes as a vaccine adjuvant and carrier system

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

Pathogen recognition and innate immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

Toll-like receptor signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

Intranasal seasonal influenza vaccine and a TLR-3 agonist, rintatolimod, induced cross-reactive IgA antibody formation against avian H5N1 and H7N9 influenza HA in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

Selection of an adjuvant for seasonal influenza vaccine in elderly people: modelling immunogenicity from a randomized trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

Safety and immunogenicity of a recombinant hemagglutinin influenza-flagellin fusion vaccine (VAX125) in healthy young adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

Immunogenicity of intradermal trivalent influenza vaccine with topical imiquimod: a double blind randomized controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

Combining viral vectored and protein-in-adjuvant vaccines against the blood-stage malaria antigen AMA1: report on a phase 1a clinical trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

A novel liposomal adjuvant system, CAF01, promotes long-lived Mycobacterium tuberculosis-specific T-cell responses in human

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

Sensing of Mycobacterium tuberculosis and consequences to both host and bacillus

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

Towards understanding the functional diversity of cell wall mycolic acids of Mycobacterium tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

Growth of Mycobacterium tuberculosis biofilms containing free mycolic acids and harbouring drug-tolerant bacteria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

The Mycobacterium tuberculosis cell wall component mycolic acid elicits pathogen-associated host innate immune responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

Foamy macrophages from tuberculous patients' granulomas constitute a nutrient-rich reservoir for M. tuberculosis persistence

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

Mycobacterium tuberculosis uses host triacylglycerol to accumulate lipid droplets and acquires a dormancy-like phenotype in lipid-loaded macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

The effect of oxygenated mycolic acid composition on cell wall function and macrophage growth in Mycobacterium tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

Oxygenated mycolic acids are necessary for virulence of Mycobacterium tuberculosis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

Molecular structure of the Mycobacterium tuberculosis virulence factor, mycolic acid, determines the elicited inflammatory pattern.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

A mycolic acid-specific CD1-restricted T cell population contributes to acute and memory immune responses in human tuberculosis infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

Immunization with a mycobacterial lipid vaccine improves pulmonary pathology in the guinea pig model of tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

Extravascular coagulation and fibrinolysis in murine lung inflammation induced by the mycobacterial cord factor trehalose-6,6'-dimycolate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

Cord factor (alpha,alpha-trehalose 6,6'-dimycolate) inhibits fusion between phospholipid vesicles

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

Cord factor and peptidoglycan recapitulate the Th17-promoting adjuvant activity of mycobacteria through mincle/CARD9 signaling and the inflammasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

Molecular and supra-molecular structure related differences in toxicity and granulomatogenic activity of mycobacterial cord factor in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

The Mycobacterium tuberculosis MEP (2C-methyl-d-erythritol 4-phosphate) pathway as a new drug target

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

Trehalose 6,6'-dimycolate and lipid in the pathogenesis of caseating granulomas of tuberculosis in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

Trans-cyclopropanation of mycolic acids on trehalose dimycolate suppresses Mycobacterium tuberculosis -induced inflammation and virulence

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

Mycobacterium tuberculosis controls host innate immune activation through cyclopropane modification of a glycolipid effector molecule

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

Mycolic acid modification by the mmaA4 gene of M. tuberculosis modulates IL-12 production

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

Cationic liposomes formulated with synthetic mycobacterial cordfactor (CAF01): a versatile adjuvant for vaccines with different immunological requirements

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

Small cationic DDA:TDB liposomes as protein vaccine adjuvants obviate the need for TLR agonists in inducing cellular and humoral responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

The Mincle-activating adjuvant TDB induces MyD88-dependent Th1 and Th17 responses through IL-1R signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

Adjuvanted HLA-supertype restricted subdominant peptides induce new T-cell immunity during untreated HIV-1-infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

Direct recognition of the mycobacterial glycolipid, trehalose dimycolate, by C-type lectin Mincle

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

Cutting edge: Mincle is essential for recognition and adjuvanticity of the mycobacterial cord factor and its synthetic analog trehalose-dibehenate

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

MCL and Mincle: C-Type Lectin Receptors That Sense Damaged Self and Pathogen-Associated Molecular Patterns

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

C-type lectin MCL is an FcRγ-coupled receptor that mediates the adjuvanticity of mycobacterial cord factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

The C-type lectin receptor CLECSF8 (CLEC4D) is expressed by myeloid cells and triggers cellular activation through Syk kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

C-Type Lectin Receptor MCL Facilitates Mincle Expression and Signaling through Complex Formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

Mycobacterial receptor, Clec4d (CLECSF8, MCL), is coregulated with Mincle and upregulated on mouse myeloid cells following microbial challenge.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

The C-type lectin receptor CLECSF8/CLEC4D is a key component of anti-mycobacterial immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

Characterization of the receptors for mycobacterial cord factor in Guinea pig.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

Contribution of MINCLE-SYK Signaling to Activation of Primary Human APCs by Mycobacterial Cord Factor and the Novel Adjuvant TDB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

The biology of Mycobacterium cord factor and roles in pathogen-host interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

Structure-activity relationship of mycoloyl glycolipids derived from Rhodococcus sp. 4306.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

Corynomycolic acid-containing glycolipids signal through the pattern recognition receptor Mincle

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

Mycolyltransferase-mediated glycolipid exchange in Mycobacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

Structural requirements for glycolipid antigen recognition by CD1b-restricted T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

T-cell responses to CD1-presented lipid antigens in humans with Mycobacterium tuberculosis infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

The mycobacterial glycolipid glucose monomycolate induces a memory T cell response comparable to a model protein antigen and no B cell response upon experimental vaccination of cattle

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

Th1-skewed tissue responses to a mycolyl glycolipid in mycobacteria-infected rhesus macaques

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

A microbial glycolipid functions as a new class of target antigen for delayed-type hypersensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

Targeted delivery of mycobacterial antigens to human dendritic cells via Siglec-7 induces robust T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

Mycolic acids constitute a scaffold for mycobacterial lipid antigens stimulating CD1-restricted T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

Adjuvant properties of a simplified C32 monomycolyl glycerol analogue

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

A simple mycobacterial monomycolated glycerol lipid has potent immunostimulatory activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

Glycerol monomycolate is a novel ligand for the human, but not mouse macrophage inducible C-type lectin, Mincle

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

Induction of CD8+ T-cell responses against subunit antigens by the novel cationic liposomal CAF09 adjuvant

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

Maturation of human dendritic cells by cell wall skeleton of Mycobacterium bovis bacillus Calmette-Guérin: involvement of toll-like receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

Innate immune therapy with a Bacillus Calmette-Guérin cell wall skeleton after radical surgery for non-small cell lung cancer: a case-control study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

The mycobacterial cell wall: structure, biosynthesis and sites of drug action.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

Mycobacterial lipoarabinomannans: modulators of dendritic cell function and the apoptotic response

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

Lipoarabinomannan and related glycoconjugates: structure, biogenesis and role in Mycobacterium tuberculosis physiology and host-pathogen interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

Lipoarabinomannan mannose caps do not affect mycobacterial virulence or the induction of protective immunity in experimental animal models of infection and have minimal impact on in vitro inflammatory responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

The mannose cap of mycobacterial lipoarabinomannan does not dominate the Mycobacterium-host interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

Collectin CL-LK Is a Novel Soluble Pattern Recognition Receptor for Mycobacterium tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

Dectin-2 is a direct receptor for mannose-capped lipoarabinomannan of mycobacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

Inducible IL-2 production by dendritic cells revealed by global gene expression analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

Effect of lipoarabinomannan from Mycobacterium avium subsp avium in Freund's incomplete adjuvant on the immune response of cattle

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

Key roles of adjuvants in modern vaccines

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

The mycobacterial cord factor adjuvant analogue trehalose-6,6'-dibehenate (TDB) activates the Nlrp3 inflammasome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

The dectin-1/inflammasome pathway is responsible for the induction of protective T-helper 17 responses that discriminate between yeasts and hyphae of Candida albicans

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

SYK kinase signaling and the NLRP3 inflammasome in antifungal immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

Mycobacterium tuberculosis and TLR2 agonists inhibit induction of type I IFN and class I MHC antigen cross processing by TLR9

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

Mincle suppresses Toll-like receptor 4 activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

Lipoarabinomannan-Responsive Polycytotoxic T Cells Are Associated with Protection in Human Tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

Mycolic acid-specific T cells protect against Mycobacterium tuberculosis infection in a humanized transgenic mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

The tuberculosis vaccine H4:IC31 is safe and induces a persistent polyfunctional CD4 T cell response in South African adults: A randomized controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

Safety and immunogenicity of candidate vaccine M72/AS01E in adolescents in a TB endemic setting

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F14760584.2016.1187067

10.1080/14760584.2016.1187067

21 January 2018

Identifiers

DOI

1 reference

14 September 2017

1 reference

PubMed ID

27206681