(Q39749097)

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17(R),18(S)-epoxyeicosatetraenoic acid, a potent eicosapentaenoic acid (EPA) derived regulator of cardiomyocyte contraction: structure-activity relationships and stable analogues

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scholarly article

1 reference

Europe PubMed Central

14 September 2017

17(R),18(S)-epoxyeicosatetraenoic acid, a potent eicosapentaenoic acid (EPA) derived regulator of cardiomyocyte contraction: structure-activity relationships and stable analogues (English)

1 reference

Europe PubMed Central

14 September 2017

object named as

John R Falck

1

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2

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Gerd Wallukat

1 reference

Europe PubMed Central

14 September 2017

author name string

Narender Puli

3

1 reference

Europe PubMed Central

14 September 2017

Mohan Goli

4

1 reference

Europe PubMed Central

14 September 2017

Cosima Arnold

5

1 reference

Europe PubMed Central

14 September 2017

Anne Konkel

6

1 reference

Europe PubMed Central

14 September 2017

Michael Rothe

7

1 reference

Europe PubMed Central

14 September 2017

Robert Fischer

8

1 reference

Europe PubMed Central

14 September 2017

Dominik N Müller

9

1 reference

Europe PubMed Central

14 September 2017

Wolf-Hagen Schunck

10

1 reference

Europe PubMed Central

14 September 2017

language of work or name

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publication date

1 June 2011

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Europe PubMed Central

14 September 2017

Journal of Medicinal Chemistry

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Europe PubMed Central

14 September 2017

54

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Europe PubMed Central

14 September 2017

12

1 reference

Europe PubMed Central

14 September 2017

4109-4118

1 reference

Europe PubMed Central

14 September 2017

Rapid synthesis of an array of trisubstituted urea-based soluble epoxide hydrolase inhibitors facilitated by a novel solid-phase method

1 reference

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New antiarrhythmic drugs for treatment of atrial fibrillation.

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Reduced prostaglandin F2 alpha release from blood mononuclear leukocytes after oral supplementation of omega3 fatty acids: the OmegAD study

1 reference

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Stereoselective epoxidation of the last double bond of polyunsaturated fatty acids by human cytochromes P450.

1 reference

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20-125Iodo-14,15-epoxyeicosa-5(Z)-enoic acid: a high-affinity radioligand used to characterize the epoxyeicosatrienoic acid antagonist binding site

1 reference

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Detection of omega-3 oxylipins in human plasma and response to treatment with omega-3 acid ethyl esters

1 reference

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Omega-3 polyunsaturated fatty acids and cardiovascular diseases

1 reference

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Docosahexaenoic acid (DHA) and cardiovascular disease risk factors

1 reference

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Cardiovascular disease prevention and treatment

1 reference

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Metabolism of eicosapentaenoic and docosahexaenoic acids by recombinant human cytochromes P450.

1 reference

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Direct protective effects of poly-unsaturated fatty acids, DHA and EPA, against activation of cardiac late sodium current: a mechanism for ischemia selectivity

1 reference

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14 September 2017

Omega-3 fatty acids and cardiovascular disease: a case for omega-3 index as a new risk factor

1 reference

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14 September 2017

Action of epoxyeicosatrienoic acids on cellular function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122156

14 September 2017

Cardiovascular therapeutic aspects of soluble epoxide hydrolase inhibitors.

1 reference

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14 September 2017

cis-dihydroxylation of unsaturated potassium alkyl- and aryltrifluoroborates

1 reference

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14 September 2017

Cyclooxygenases, peroxide tone and the allure of fish oil.

1 reference

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14 September 2017

Eicosapentaenoic acid metabolism by cytochrome P450 enzymes of the CYP2C subfamily

1 reference

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Omega 3-fatty acids: health benefits and cellular mechanisms of action

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Clinical prevention of sudden cardiac death by n-3 polyunsaturated fatty acids and mechanism of prevention of arrhythmias by n-3 fish oils

1 reference

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The CYP4A isoforms hydroxylate epoxyeicosatrienoic acids to form high affinity peroxisome proliferator-activated receptor ligands

1 reference

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Early protection against sudden death by n-3 polyunsaturated fatty acids after myocardial infarction: time-course analysis of the results of the Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto Miocardico (GISSI)-Prevenzione.

1 reference

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14 September 2017

Potent urea and carbamate inhibitors of soluble epoxide hydrolases

1 reference

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14 September 2017

Effects of long-chain polyunsaturated fatty acids on the contraction of neonatal rat cardiac myocytes

1 reference

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Free, long-chain, polyunsaturated fatty acids reduce membrane electrical excitability in neonatal rat cardiac myocytes

1 reference

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Discovery of a highly potent, selective, and bioavailable soluble epoxide hydrolase inhibitor with excellent ex vivo target engagement

1 reference

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14,15-Epoxyeicosa-5,8,11-trienoic acid (14,15-EET) surrogates containing epoxide bioisosteres: influence upon vascular relaxation and soluble epoxide hydrolase inhibition.

1 reference

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Arachidonic acid-metabolizing cytochrome P450 enzymes are targets of {omega}-3 fatty acids

1 reference

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Prevention and termination of beta-adrenergic agonist-induced arrhythmias by free polyunsaturated fatty acids in neonatal rat cardiac myocytes

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Epoxygenase metabolites of docosahexaenoic and eicosapentaenoic acids inhibit platelet aggregation at concentrations below those affecting thromboxane synthesis

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Effect of low doses of n-3 fatty acids on cardiovascular diseases in 4,837 post-myocardial infarction patients: design and baseline characteristics of the Alpha Omega Trial

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17,18-epoxyeicosatetraenoic acid targets PPARγ and p38 mitogen-activated protein kinase to mediate its anti-inflammatory effects in the lung: role of soluble epoxide hydrolase

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Relaxing effects of 17(18)-EpETE on arterial and airway smooth muscles in human lung

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20 August 2018

Characterization of epoxyeicosatrienoic acid binding site in U937 membranes using a novel radiolabeled agonist, 20-125i-14,15-epoxyeicosa-8(Z)-enoic acid

1 reference

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Dietary n-3 polyunsaturated fatty acids and direct renin inhibition improve electrical remodeling in a model of high human renin hypertension

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The vasodilator 17,18-epoxyeicosatetraenoic acid targets the pore-forming BK alpha channel subunit in rodents.

1 reference

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Mouse Cyp4a isoforms: enzymatic properties, gender- and strain-specific expression, and role in renal 20-hydroxyeicosatetraenoic acid formation

1 reference

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Human CYP1A1 variants lead to differential eicosapentaenoic acid metabolite patterns

1 reference

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20 August 2018

Arachidonic and eicosapentaenoic acid metabolism by human CYP1A1: highly stereoselective formation of 17(R),18(S)-epoxyeicosatetraenoic acid.

1 reference

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14,15-Epoxyeicosa-5(Z)-enoic acid: a selective epoxyeicosatrienoic acid antagonist that inhibits endothelium-dependent hyperpolarization and relaxation in coronary arteries

1 reference

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Cytochrome P450-dependent eicosapentaenoic acid metabolites are novel BK channel activators

1 reference

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Urinary excretion of diols derived from eicosapentaenoic acid during N-3 fatty acid ingestion by man

1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/21591683

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inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/21591683

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based on heuristic

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1 reference

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1 reference

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based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1021/JM200132Q

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Europe PubMed Central

14 September 2017

release_6lqv4d345jflvadjsdrgn6i7ii

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https://api.fatcat.wiki/v0/release/6lqv4d345jflvadjsdrgn6i7ii

24 November 2022

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mapped directly with Wikidata item

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Europe PubMed Central

14 September 2017

1 reference

Europe PubMed Central

14 September 2017

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