(Q39751684)

14 September 2017

title

Structure of the CED-4-CED-9 complex provides insights into programmed cell death in Caenorhabditis elegans (English)

1 reference

Programmed cell death activator egl-1 CELE_F23B12.9

14 September 2017

main subject

Caenorhabditis elegans

0 references

1 reference

Apoptosis regulator ced-9 CELE_T07C4.8

1 reference

Cell death protein 3 subunit p17 CELE_C48D1.2

1 reference

Cell death protein 4 CELE_C35D10.9

1 reference

1 reference

David Kokel

8

0 references

Qun Liu

object named as

Qun Liu

5

0 references

Ding Xue

object named as

Ding Xue

11

0 references

Jiaqing He

object named as

Jiaqing He

6

0 references

author name string

Nieng Yan

1

1 reference

14 September 2017

Jijie Chai

2

1 reference

14 September 2017

Eui Seung Lee

3

1 reference

14 September 2017

Lichuan Gu

4

1 reference

14 September 2017

Jia-Wei Wu

7

1 reference

14 September 2017

Huilin Li

9

1 reference

14 September 2017

Quan Hao

10

1 reference

14 September 2017

Yigong Shi

12

1 reference

14 September 2017

language of work or name

English

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publication date

1 October 2005

1 reference

14 September 2017

1 reference

14 September 2017

volume

437

1 reference

14 September 2017

issue

7060

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14 September 2017

page(s)

831-837

1 reference

Worms, life, and death (Nobel lecture).

14 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04002

The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04002

The Caenorhabditis elegans cell-death protein CED-3 is a cysteine protease with substrate specificities similar to those of the human CPP32 protease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04002

21 January 2018

Caspases: enemies within

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04002

Interaction of CED-4 with CED-3 and CED-9: a molecular framework for cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04002

Direct physical interaction between the Caenorhabditis elegans 'death proteins' CED-3 and CED-4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04002

Caenorhabditis elegans CED-4 stimulates CED-3 processing and CED-3-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04002

Interaction and regulation of subcellular localization of CED-4 by CED-9

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04002

Essential role of CED-4 oligomerization in CED-3 activation and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04002

C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04002

Translocation of C. elegans CED-4 to nuclear membranes during programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04002

CED-4 induces chromatin condensation in Schizosaccharomyces pombe and is inhibited by direct physical association with CED-9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04002

Interaction between the C. elegans cell-death regulators CED-9 and CED-4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04002

The C. elegans protein EGL-1 is required for programmed cell death and interacts with the Bcl-2-like protein CED-9

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04002

Caenorhabditis elegans EGL-1 disrupts the interaction of CED-9 with CED-4 and promotes CED-3 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04002

Demonstration of the in vivo interaction of key cell death regulators by structure-based design of second-site suppressors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04002

Structural, biochemical, and functional analyses of CED-9 recognition by the proapoptotic proteins EGL-1 and CED-4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04002

Structure of the apoptotic protease-activating factor 1 bound to ADP

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04002

Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04002

Protein structure comparison by alignment of distance matrices

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04002

Structure and function of Cdc6/Cdc18: implications for origin recognition and checkpoint control

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04002

Conformational changes induced by nucleotide binding in Cdc6/ORC from Aeropyrum pernix

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04002

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04002

ATP-activated oligomerization as a mechanism for apoptosis regulation: fold and mechanism prediction for CED-4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04002

Unique structural features of a BCL-2 family protein CED-9 and biophysical characterization of CED-9/EGL-1 interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04002

Protease activity of in vitro transcribed and translated Caenorhabditis elegans cell death gene (ced-3) product

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04002

An alternatively spliced C. elegans ced-4 RNA encodes a novel cell death inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04002

Mutational analysis of the interacting cell death regulators CED-9 and CED-4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04002

Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04002

Advances in direct methods for protein crystallography

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04002

Automated MAD and MIR structure solution

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04002

Methods used in the structure determination of bovine mitochondrial F1 ATPase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04002

Improved methods for building protein models in electron density maps and the location of errors in these models

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04002

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04002

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04002

Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04002

21 January 2018

Identifiers

DOI

10.1038/NATURE04002

1 reference

Dimensions Publication ID

14 September 2017

1016162000

0 references

1 reference