(Q39756110)

English

The telomerase antagonist, imetelstat, efficiently targets glioblastoma tumor-initiating cells leading to decreased proliferation and tumor growth

scientific article

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

14 September 2017

The telomerase antagonist, imetelstat, efficiently targets glioblastoma tumor-initiating cells leading to decreased proliferation and tumor growth (English)

1 reference

Europe PubMed Central

14 September 2017

1 reference

based on heuristic

inferred from title

Woodring E. Wright

8

object named as

Woodring E Wright

1 reference

Europe PubMed Central

14 September 2017

9

object named as

Jerry W Shay

1 reference

Europe PubMed Central

14 September 2017

5

object named as

Kimmo J Hatanpaa

1 reference

Europe PubMed Central

14 September 2017

author name string

Calin O Marian

1

1 reference

Europe PubMed Central

14 September 2017

Steve K Cho

2

1 reference

Europe PubMed Central

14 September 2017

Brian M McEllin

3

1 reference

Europe PubMed Central

14 September 2017

Elizabeth A Maher

4

1 reference

Europe PubMed Central

14 September 2017

Christopher J Madden

6

1 reference

Europe PubMed Central

14 September 2017

Bruce E Mickey

7

1 reference

Europe PubMed Central

14 September 2017

Robert M Bachoo

10

1 reference

Europe PubMed Central

14 September 2017

language of work or name

0 references

publication date

1 January 2010

1 reference

Europe PubMed Central

14 September 2017

Clinical Cancer Research

1 reference

Europe PubMed Central

14 September 2017

16

1 reference

Europe PubMed Central

14 September 2017

154-163

1 reference

Europe PubMed Central

14 September 2017

1

1 reference

Europe PubMed Central

14 September 2017

Glioblastoma stem cells resistant to temozolomide-induced autophagy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883447

22 September 2017

Combination of adenoviral virotherapy and temozolomide chemotherapy eradicates malignant glioma through autophagic and apoptotic cell death in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883447

22 September 2017

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883447

22 September 2017

Malignant gliomas in adults

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883447

22 September 2017

Telomerase inhibitor GRN163L inhibits myeloma cell growth in vitro and in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883447

22 September 2017

Telomeres and aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883447

22 September 2017

Genomic expression patterns distinguish long-term from short-term glioblastoma survivors: a preliminary feasibility study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883447

22 September 2017

Angiogenesis and gliomas: current issues and development of surrogate markers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883447

22 September 2017

Telomerase and cancer therapeutics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883447

22 September 2017

Malignant astrocytic glioma: genetics, biology, and paths to treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883447

22 September 2017

CD133 negative glioma cells form tumors in nude rats and give rise to CD133 positive cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883447

22 September 2017

Ectopic telomerase expression inhibits neuronal differentiation of NT2 neural progenitor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883447

22 September 2017

Brain tumour stem cells: the undercurrents of human brain cancer and their relationship to neural stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883447

22 September 2017

Specific telomere dysfunction induced by GRN163L increases radiation sensitivity in breast cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883447

22 September 2017

Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumour-initiating cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883447

22 September 2017

Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883447

22 September 2017

Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883447

22 September 2017

Autophagic cell death of malignant glioma cells induced by a conditionally replicating adenovirus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883447

22 September 2017

Genomic profiling identifies discrete deletions associated with translocations in glioblastoma multiforme.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883447

22 September 2017

Effects of a novel telomerase inhibitor, GRN163L, in human breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883447

22 September 2017

In vivo inhibition of lung cancer by GRN163L: a novel human telomerase inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883447

22 September 2017

Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883447

22 September 2017

Identification of human brain tumour initiating cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883447

22 September 2017

Genetic alterations and in vivo tumorigenicity of neurospheres derived from an adult glioblastoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883447

22 September 2017

Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883447

22 September 2017

Factors influencing survival in high-grade gliomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883447

22 September 2017

Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883447

22 September 2017

Identification of a cancer stem cell in human brain tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883447

22 September 2017

Tight junctions of the blood-brain barrier: development, composition and regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883447

22 September 2017

Telomerase: a target for cancer therapeutics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883447

22 September 2017

Telomerase in brain tumors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883447

22 September 2017

Telomerase activity in primary and secondary glioblastomas multiforme as a novel molecular tumor marker

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883447

22 September 2017

Telomere reduction and telomerase inactivation during neuronal cell differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883447

25 September 2017

Telomerase expression in gliomas including the nonastrocytic tumors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883447

20 August 2018

Telomerase activity in human gliomas.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883447

20 August 2018

Differential telomerase expression in human primary intracranial tumors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883447

20 August 2018

Telomerase activity in human brain tumours.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883447

20 August 2018

Correlation of clinical features and telomerase activity in human gliomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/20048334

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lipid modification of GRN163, an N3'-->P5' thio-phosphoramidate oligonucleotide, enhances the potency of telomerase inhibition

1 reference

https://pubmed.ncbi.nlm.nih.gov/20048334

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human neural precursor cells express low levels of telomerase in vitro and show diminishing cell proliferation with extensive axonal outgrowth following transplantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20048334

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1158/1078-0432.CCR-09-2850

1 reference

Europe PubMed Central

14 September 2017

release_pyl2ptkbwnbshnu6upr4isjawu

1 reference

https://api.fatcat.wiki/v0/release/pyl2ptkbwnbshnu6upr4isjawu

24 November 2022

based on heuristic

mapped directly with Wikidata item

1 reference

Europe PubMed Central

14 September 2017

1 reference

Europe PubMed Central

14 September 2017

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q39756110&oldid=2089974679"