(Q39782235)

English

A new PG13-based packaging cell line for stable production of clinical-grade self-inactivating gamma-retroviral vectors using targeted integration.

scientific article published on 29 October 2009

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scholarly article

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11 February 2020

A new PG13-based packaging cell line for stable production of clinical-grade self-inactivating gamma-retroviral vectors using targeted integration (English)

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11 February 2020

Leonor Gama-Norton

4

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11 February 2020

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11 February 2020

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R Loew

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11 February 2020

Y Meyer

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11 February 2020

K Kuehlcke

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11 February 2020

D Wirth

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11 February 2020

H Hauser

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11 February 2020

M Grez

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11 February 2020

S Thornhill

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11 February 2020

A Thrasher

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11 February 2020

C Baum

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11 February 2020

A Schambach

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11 February 2020

publication date

29 October 2009

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11 February 2020

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11 February 2020

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11 February 2020

2

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11 February 2020

272-280

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11 February 2020

The future of gene therapy

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A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency

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Physiological promoters reduce the genotoxic risk of integrating gene vectors

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A new generation of retroviral producer cells: predictable and stable virus production by Flp-mediated site-specific integration of retroviral vectors.

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21 January 2018

The use of recombinase mediated cassette exchange in retroviral vector producer cell lines: predictability and efficiency by transgene exchange

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21 January 2018

Evaluation of retroviral vector design in defined chromosomal loci by Flp-mediated cassette replacement.

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21 January 2018

Gene therapy of X-linked severe combined immunodeficiency by use of a pseudotyped gammaretroviral vector

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Use of mutated FLP recognition target (FRT) sites for the exchange of expression cassettes at defined chromosomal loci

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Effects of retroviral vector design on expression of human adenosine deaminase in murine bone marrow transplant recipients engrafted with genetically modified cells

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Overcoming promoter competition in packaging cells improves production of self-inactivating retroviral vectors

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Characterization of the chicken beta-globin insulator

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Transgene optimization significantly improves SIN vector titers, gp91phox expression and reconstitution of superoxide production in X-CGD cells.

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Self-inactivating gammaretroviral vectors for gene therapy of X-linked severe combined immunodeficiency.

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Tight control of gene expression in mammalian cells by tetracycline-responsive promoters

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A transient three-plasmid expression system for the production of high titer retroviral vectors

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Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

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Context Dependence of Different Modules for Posttranscriptional Enhancement of Gene Expression from Retroviral Vectors

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A third-generation lentivirus vector with a conditional packaging system

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Design and production of retro- and lentiviral vectors for gene expression in hematopoietic cells

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Construction and properties of retrovirus packaging cells based on gibbon ape leukemia virus

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Improving transcriptional termination of self-inactivating gamma-retroviral and lentiviral vectors

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High-titer packaging cells producing recombinant retroviruses resistant to human serum

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Identifiers

10.1038/GT.2009.134

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11 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19865181%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

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