(Q39941137)

English

Transgene optimization significantly improves SIN vector titers, gp91phox expression and reconstitution of superoxide production in X-CGD cells.

scientific article published on 11 September 2008

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Europe PubMed Central

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14 January 2020

Transgene optimization significantly improves SIN vector titers, gp91phox expression and reconstitution of superoxide production in X-CGD cells (English)

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14 January 2020

Bibiana Moreno-Carranza

1

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14 January 2020

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14 January 2020

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M Gentsch

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14 January 2020

A Schambach

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14 January 2020

G Santilli

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14 January 2020

E Rudolf

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14 January 2020

M F Ryser

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14 January 2020

S Haria

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14 January 2020

A J Thrasher

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14 January 2020

C Baum

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14 January 2020

S Brenner

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14 January 2020

M Grez

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14 January 2020

publication date

11 September 2008

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14 January 2020

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14 January 2020

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14 January 2020

1

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14 January 2020

111-118

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14 January 2020

https://scigraph.springernature.com/pub.10.1038/gt.2008.143

0 references

Correction of ADA-SCID by stem cell gene therapy combined with nonmyeloablative conditioning

1 reference

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Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease

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Successful reconstitution of immunity in ADA-SCID by stem cell gene therapy following cessation of PEG-ADA and use of mild preconditioning

1 reference

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21 January 2018

Gene therapy of X-linked severe combined immunodeficiency by use of a pseudotyped gammaretroviral vector

1 reference

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21 January 2018

Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1.

1 reference

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21 January 2018

Side effects of retroviral gene transfer into hematopoietic stem cells

1 reference

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21 January 2018

Mutagenesis and oncogenesis by chromosomal insertion of gene transfer vectors.

1 reference

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21 January 2018

Chance or necessity? Insertional mutagenesis in gene therapy and its consequences

1 reference

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21 January 2018

Gene therapy for severe combined immunodeficiency: are we there yet?

1 reference

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21 January 2018

A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency

1 reference

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21 January 2018

LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1

1 reference

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21 January 2018

Activation of the T-cell oncogene LMO2 after gene therapy for X-linked severe combined immunodeficiency

1 reference

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21 January 2018

Chronic granulomatous disease.

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.143

21 January 2018

The NADPH oxidase and chronic granulomatous disease

1 reference

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21 January 2018

Genetic, biochemical, and clinical features of chronic granulomatous disease.

1 reference

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21 January 2018

Severe phenotype of chronic granulomatous disease presenting in a female with a de novo mutation in gp91-phox and a non familial, extremely skewed X chromosome inactivation

1 reference

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21 January 2018

Chronic granulomatous disease. Report on a national registry of 368 patients

1 reference

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21 January 2018

Inserting optimism into gene therapy.

1 reference

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21 January 2018

Overcoming promoter competition in packaging cells improves production of self-inactivating retroviral vectors

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.143

21 January 2018

Gene targeting of X chromosome-linked chronic granulomatous disease locus in a human myeloid leukemia cell line and rescue by expression of recombinant gp91phox

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.143

21 January 2018

Activity analysis of housekeeping promoters using self-inactivating lentiviral vector delivery into the mouse retina.

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.143

21 January 2018

Self-inactivating gammaretroviral vectors for gene therapy of X-linked severe combined immunodeficiency.

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.143

21 January 2018

Multilineage hematopoietic reconstitution without clonal selection in ADA-SCID patients treated with stem cell gene therapy

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.143

21 January 2018

Retroviral integration and human gene therapy

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.143

21 January 2018

Vector integration is nonrandom and clustered and influences the fate of lymphopoiesis in SCID-X1 gene therapy

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.143

21 January 2018

Gammaretrovirus-mediated correction of SCID-X1 is associated with skewed vector integration site distribution in vivo

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.143

21 January 2018

Insertional mutagenesis identifies genes that promote the immortalization of primary bone marrow progenitor cells

1 reference

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21 January 2018

Retroviral vector insertion sites associated with dominant hematopoietic clones mark "stemness" pathways

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21 January 2018

The MDS1-EVI1 gene complex as a retrovirus integration site: impact on behavior of hematopoietic cells and implications for gene therapy

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21 January 2018

Leukemias following retroviral transfer of multidrug resistance 1 (MDR1) are driven by combinatorial insertional mutagenesis.

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https://api.crossref.org/works/10.1038%2FGT.2008.143

21 January 2018

A chromatin insulator protects retrovirus vectors from chromosomal position effects

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https://api.crossref.org/works/10.1038%2FGT.2008.143

21 January 2018

An experimental system for the evaluation of retroviral vector design to diminish the risk for proto-oncogene activation

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21 January 2018

Cell-culture assays reveal the importance of retroviral vector design for insertional genotoxicity

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21 January 2018

Physiological promoters reduce the genotoxic risk of integrating gene vectors

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Hematopoietic stem cell gene transfer in a tumor-prone mouse model uncovers low genotoxicity of lentiviral vector integration

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Analysis of factor VIII mediated suppression of lentiviral vector titres

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Optimization of self-complementary AAV vectors for liver-directed expression results in sustained correction of hemophilia B at low vector dose

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Vector design for expression of O6-methylguanine-DNA methyltransferase in hematopoietic cells

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Nuclear-localizing O6-benzylguanine-resistant GFP-MGMT fusion protein as a novel in vivo selection marker

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Polyclonal long-term MFGS-gp91phox marking in rhesus macaques after nonmyeloablative transplantation with transduced autologous peripheral blood progenitor cells.

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High-level transduction and gene expression in hematopoietic repopulating cells using a human immunodeficiency [correction of imunodeficiency] virus type 1-based lentiviral vector containing an internal spleen focus forming virus promoter

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

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Kinetic microplate assay for superoxide production by neutrophils and other phagocytic cells

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7 January 2021

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