(Q39788628)

14 September 2017

Ikappa B kinasebeta/nuclear factor-kappaB activation controls the development of liver metastasis by way of interleukin-6 expression (English)

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14 September 2017

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9

Michael Karin

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14 September 2017

Shin Maeda

1

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14 September 2017

Yohko Hikiba

2

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14 September 2017

Kei Sakamoto

3

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14 September 2017

Hayato Nakagawa

4

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14 September 2017

Yoshihiro Hirata

5

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14 September 2017

Yoku Hayakawa

6

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14 September 2017

Ayako Yanai

7

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14 September 2017

Keiji Ogura

8

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14 September 2017

Masao Omata

10

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14 September 2017

language of work or name

English

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publication date

1 December 2009

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14 September 2017

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14 September 2017

50

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14 September 2017

6

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14 September 2017

1851-1860

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Tumor metastasis: mechanistic insights and clinical challenges

14 September 2017

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Metastasis: a therapeutic target for cancer

21 January 2018

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NF-kappaB at the crossroads of life and death

21 January 2018

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Missing pieces in the NF-kappaB puzzle

21 January 2018

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NF-kappaB in cancer: from innocent bystander to major culprit

21 January 2018

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IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer

21 January 2018

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NF-kappaB functions as a tumour promoter in inflammation-associated cancer

21 January 2018

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IKKbeta couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis

21 January 2018

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Back to the future: COX-2 inhibitors for chemoprevention and cancer therapy

21 January 2018

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The protein kinase PKR is required for macrophage apoptosis after activation of Toll-like receptor 4.

21 January 2018

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TGF-beta suppresses tumor progression in colon cancer by inhibition of IL-6 trans-signaling.

21 January 2018

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Interleukin 1 (IL-1)-dependent melanoma hepatic metastasis in vivo; increased endothelial adherence by IL-1-induced mannose receptors and growth factor production in vitro

21 January 2018

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Inflammation and cancer: how hot is the link?

21 January 2018

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Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6

21 January 2018

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Interleukin-6 contributes to growth in cholangiocarcinoma cells by aberrant promoter methylation and gene expression

21 January 2018

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An oriental herbal cocktail, ka-mi-kae-kyuk-tang, exerts anti-cancer activities by targeting angiogenesis, apoptosis and metastasis.

21 January 2018

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Interleukin-6 induces transcriptional activation of vascular endothelial growth factor (VEGF) in astrocytes in vivo and regulates VEGF promoter activity in glioblastoma cells via direct interaction between STAT3 and Sp1.

21 January 2018

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Selective inhibition of NF-kappaB activation by a peptide that blocks the interaction of NEMO with the IkappaB kinase complex

21 January 2018

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Gender disparity in liver cancer due to sex differences in MyD88-dependent IL-6 production

21 January 2018

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Mutations in the EGFR kinase domain mediate STAT3 activation via IL-6 production in human lung adenocarcinomas

21 January 2018

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Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis

21 January 2018

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Liver failure and defective hepatocyte regeneration in interleukin-6-deficient mice.

21 January 2018

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Normal liver regeneration and liver cell apoptosis after partial hepatectomy in tumor necrosis factor-alpha-deficient mice

21 January 2018

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Initiation of liver growth by tumor necrosis factor: deficient liver regeneration in mice lacking type I tumor necrosis factor receptor

21 January 2018

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21 January 2018

Inflammation and cancer

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Mucosal and enterocyte IL-6 production during sepsis and endotoxemia--role of transcription factors and regulation by the stress response

21 January 2018

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Targeting tumor-associated macrophages as a novel strategy against breast cancer

21 January 2018

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Distinct role of macrophages in different tumor microenvironments

21 January 2018

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Loss of IkkB promotes migration and proliferation of mouse embryo fibroblast cells

21 January 2018

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Inhibition of constitutive NF-kappa B activity by I kappa B alpha M suppresses tumorigenesis

21 January 2018

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Constitutive activation of NF-kappaB during progression of breast cancer to hormone-independent growth

21 January 2018

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The IKK NF-kappa B system: a treasure trove for drug development

21 January 2018

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Tocilizumab: the first interleukin-6-receptor inhibitor

21 January 2018

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Synergistic upregulation of metalloproteinase-9 by growth factors and inflammatory cytokines: an absolute requirement for transcription factor NF-kappa B

21 January 2018

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7 January 2021

IKKβ Is Required for Prevention of Apoptosis Mediated by Cell-Bound but Not by Circulating TNFα

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7 January 2021

Cutting edge: The IkappaB kinase (IKK) inhibitor, NEMO-binding domain peptide, blocks inflammatory injury in murine colitis

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7 January 2021

Clinical significance of interleukin-6 (IL-6) in the spread of gastric cancer: role of IL-6 as a prognostic factor

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7 January 2021

Evaluation of serum procalcitonin and interleukin-6 levels as markers of liver metastasis

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7 January 2021

Tumor necrosis factor-alpha-induced cyclooxygenase-2 expression via sequential activation of ceramide-dependent mitogen-activated protein kinases, and IkappaB kinase 1/2 in human alveolar epithelial cells.

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7 January 2021

Type I interferon as a novel risk factor for endothelial progenitor cell depletion and endothelial dysfunction in systemic lupus erythematosus

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7 January 2021

Identifiers

DOI

10.1002/HEP.23199

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release_gd7t6cygqjefxdkb5q7h5kk5wm

14 September 2017

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