(Q39795839)

14 September 2017

title

Suppression in mevalonate synthesis mediates antitumor effects of combined statin and gamma-tocotrienol treatment (English)

1 reference

14 September 2017

Vikram B Wali

1

1 reference

14 September 2017

Sunitha V Bachawal

series ordinal

2

1 reference

14 September 2017

Paul W Sylvester

series ordinal

3

1 reference

14 September 2017

publication date

24 September 2009

1 reference

14 September 2017

1 reference

14 September 2017

volume

44

1 reference

14 September 2017

issue

10

1 reference

14 September 2017

page(s)

925-934

1 reference

Regulation of the mevalonate pathway

14 September 2017

cites work

1 reference

12 December 2020

Regulation of HMG-CoA reductase

1 reference

12 December 2020

RAS and RHO GTPases in G1-phase cell-cycle regulation

1 reference

12 December 2020

Studies on the feed-back regulation of cholesterol synthesis

1 reference

12 December 2020

Mechanisms mediating the antiproliferative and apoptotic effects of vitamin E in mammary cancer cells

1 reference

12 December 2020

Cellular functions of the Rap1 GTP-binding protein: a pattern emerges

1 reference

12 December 2020

Effects of statins and farnesyltransferase inhibitors on the development and progression of cancer

1 reference

12 December 2020

Multivalent control of 3-hydroxy-3-methylglutaryl coenzyme A reductase. Mevalonate-derived product inhibits translation of mRNA and accelerates degradation of enzyme.

1 reference

12 December 2020

Antiproliferative and apoptotic effects of tocopherols and tocotrienols on preneoplastic and neoplastic mouse mammary epithelial cells

1 reference

12 December 2020

Synergistic antiproliferative effects of gamma-tocotrienol and statin treatment on mammary tumor cells

1 reference

12 December 2020

Studies of the isoprenoid-mediated inhibition of mevalonate synthesis applied to cancer chemotherapy and chemoprevention.

1 reference

12 December 2020

DELETION OF THE CHOLESTEROL-NEGATIVE FEEDBACK SYSTEM IN LIVER TUMORS

1 reference

12 December 2020

Crosstalk between cAMP and MAP kinase signaling in the regulation of cell proliferation

1 reference

12 December 2020

Phase I study of lovastatin, an inhibitor of the mevalonate pathway, in patients with cancer.

1 reference

12 December 2020

Selective inhibition of Rab prenylation by a phosphonocarboxylate analogue of risedronate induces apoptosis, but not S-phase arrest, in human myeloma cells.

1 reference

12 December 2020

Combined treatment of gamma-tocotrienol with statins induce mammary tumor cell cycle arrest in G1

1 reference

12 December 2020

gamma-Tocotrienol inhibits ErbB3-dependent PI3K/Akt mitogenic signalling in neoplastic mammary epithelial cells

1 reference

12 December 2020

Metastatic potential of hyperplastic alveolar nodule derived mouse mammary tumor cells following intravenous inoculation

1 reference

12 December 2020

Lovastatin-mediated G1 arrest is through inhibition of the proteasome, independent of hydroxymethyl glutaryl-CoA reductase

1 reference

12 December 2020

Gamma-tocotrienol inhibits neoplastic mammary epithelial cell proliferation by decreasing Akt and nuclear factor kappaB activity

1 reference

12 December 2020

Inhibition of the mevalonate pathway and activation of p38 MAP kinase are independently regulated by nitrogen-containing bisphosphonates in breast cancer cells

1 reference

12 December 2020

Lovastatin inhibits tumor growth and lung metastasis in mouse mammary carcinoma model: a p53-independent mitochondrial-mediated apoptotic mechanism

1 reference

12 December 2020

Isoprenoid-mediated inhibition of mevalonate synthesis: potential application to cancer

1 reference

12 December 2020

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications

1 reference

12 December 2020

Fatty acid modulation of epidermal growth factor-induced mouse mammary epithelial cell proliferation in vitro.

1 reference

12 December 2020

MAP kinase signalling pathways in cancer

1 reference

12 December 2020

Targeting the mitogen-activated protein kinase cascade to treat cancer

1 reference

12 December 2020

Rap1-mediated activation of extracellular signal-regulated kinases by cyclic AMP is dependent on the mode of Rap1 activation

1 reference

12 December 2020

Isoprenoid addition to Ras protein is the critical modification for its membrane association and transforming activity

1 reference

12 December 2020

Role of caspase-8 activation in mediating vitamin E-induced apoptosis in murine mammary cancer cells

1 reference

12 December 2020

Blocking oncogenic Ras signaling for cancer therapy

1 reference

12 December 2020

The chemoprevention of cancer by mevalonate-derived constituents of fruits and vegetables

1 reference

12 December 2020

Posttranslational modification of proteins by isoprenoids in mammalian cells

1 reference

12 December 2020

Protein prenylation: key to ras function and cancer intervention?

1 reference

12 December 2020

Cerivastatin and reports of fatal rhabdomyolysis

1 reference

12 December 2020

Emerging role of RAB GTPases in cancer and human disease

1 reference

12 December 2020

Mechanisms and consequences of activation of protein kinase B/Akt

1 reference

12 December 2020

Animal cell cycles and their control

1 reference

12 December 2020

Breast cancer growth prevention by statins

1 reference

12 December 2020

Tocotrienols regulate cholesterol production in mammalian cells by post-transcriptional suppression of 3-hydroxy-3-methylglutaryl-coenzyme A reductase

1 reference

12 December 2020

Selection and characterization in culture of mammary tumor cells with distinctive growth properties in vivo

1 reference

12 December 2020

Induction of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in human fibroblasts incubated with compactin (ML-236B), a competitive inhibitor of the reductase

1 reference

12 December 2020

Mevalonic acid-dependent degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase in vivo and in vitro

1 reference

12 December 2020

10.1007/S11745-009-3344-0

Identifiers

DOI

1 reference

14 September 2017

1 reference