(Q39812610)

14 September 2017

title

MDM2 gene amplification and protein expressions in colon carcinoma: is targeting MDM2 a new therapeutic option? (English)

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14 September 2017

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6

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14 September 2017

2

Louis Libbrecht

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14 September 2017

Monirath Hav

1

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14 September 2017

Liesbeth Ferdinande

3

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14 September 2017

Piet Pattyn

4

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14 September 2017

Stephanie Laurent

5

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14 September 2017

Marleen Praet

7

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14 September 2017

Patrick Pauwels

8

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14 September 2017

language of work or name

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27 November 2010

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14 September 2017

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14 September 2017

volume

458

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14 September 2017

issue

2

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14 September 2017

page(s)

197-203

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The p53 tumor suppressor: a master regulator of diverse cellular processes and therapeutic target in cancer

14 September 2017

cites work

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https://api.crossref.org/works/10.1007%2FS00428-010-1012-7

Restoration of p53 function leads to tumour regression in vivo

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00428-010-1012-7

The MDM2 gene amplification database

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00428-010-1012-7

Mdm2 promotes the rapid degradation of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-010-1012-7

Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-010-1012-7

Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-010-1012-7

Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-010-1012-7

Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00428-010-1012-7

A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-010-1012-7

MDM2 SNP309 Associates With Accelerated Pancreatic Adenocarcinoma Formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-010-1012-7

Analysis of mdm2 and p53 gene alterations in glioblastomas and its correlation with clinical factors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-010-1012-7

Polysomy 17 in breast cancer: clinicopathologic significance and impact on HER-2 testing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-010-1012-7

MDM2 inhibitors for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-010-1012-7

In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-010-1012-7

Temporal activation of p53 by a specific MDM2 inhibitor is selectively toxic to tumors and leads to complete tumor growth inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-010-1012-7

Small-molecule inhibitors of the MDM2-p53 protein-protein interaction to reactivate p53 function: a novel approach for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-010-1012-7

Small-molecule inhibitors of MDM2 as new anticancer therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-010-1012-7

MDM2 inhibitor MI-319 in combination with cisplatin is an effective treatment for pancreatic cancer independent of p53 function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-010-1012-7

Reactivation of p53 by novel MDM2 inhibitors: implications for pancreatic cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-010-1012-7

Small-molecule MDM2 antagonists reveal aberrant p53 signaling in cancer: implications for therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-010-1012-7

MDM2 SNP309 accelerates colorectal tumour formation in women.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-010-1012-7

MDM2 SNP309 Accelerates Tumor Formation in a Gender-Specific and Hormone-Dependent Manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-010-1012-7

Cytoplasmic tethering is involved in synergistic inhibition of p53 by Mdmx and Mdm2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-010-1012-7

The clinicopathological features and importance of p53, Rb, and mdm2 expression in phaeochromocytomas and paragangliomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-010-1012-7

Expression of mdm2 and p53 in epithelial neoplasms of the colorectum

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00428-010-1012-7

Overexpression of MDM2 oncoprotein correlates with possession of estrogen receptor alpha and lack of MDM2 mRNA splice variants in human breast cancer

21 January 2018

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12 December 2020

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12 December 2020

MDM2 gene amplification is correlated to tumor progression but not to the presence of SNP309 or TP53 mutational status in primary colorectal cancers

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12 December 2020

Tumour suppression by p53: the importance of apoptosis and cellular senescence

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12 December 2020

Expression of p53 and mdm2 mRNA and protein in colorectal carcinomas

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12 December 2020

Fluorescence in situ hybridization for MDM2 gene amplification as a diagnostic tool in lipomatous neoplasms

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12 December 2020

Tumor suppression by p53: making cells senescent

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12 December 2020

10.1007/S00428-010-1012-7

Identifiers

DOI

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14 September 2017

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