(Q39817169)

14 September 2017

title

FGF-receptor substrate 2 functions as a molecular sensor integrating external regulatory signals into the FGF pathway (English)

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14 September 2017

Wenchao Zhou

1

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14 September 2017

Xiujing Feng

2

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14 September 2017

Yingjie Wu

3

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14 September 2017

Johannes Benge

4

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14 September 2017

Zhe Zhang

5

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14 September 2017

Zhengjun Chen

6

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14 September 2017

publication date

4 August 2009

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14 September 2017

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14 September 2017

volume

19

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14 September 2017

issue

10

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14 September 2017

page(s)

1165-1177

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https://scigraph.springernature.com/pub.10.1038/cr.2009.95

14 September 2017

exact match

0 references

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Binding of Shp2 tyrosine phosphatase to FRS2 is essential for fibroblast growth factor-induced PC12 cell differentiation

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FRS2 proteins recruit intracellular signaling pathways by binding to diverse targets on fibroblast growth factor and nerve growth factor receptors

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Novel recognition motif on fibroblast growth factor receptor mediates direct association and activation of SNT adapter proteins

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Stimulation of phosphatidylinositol 3-kinase by fibroblast growth factor receptors is mediated by coordinated recruitment of multiple docking proteins

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Docking protein FRS2 links the protein tyrosine kinase RET and its oncogenic forms with the mitogen-activated protein kinase signaling cascade

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FRS2 PTB domain conformation regulates interactions with divergent neurotrophic receptors

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Fibroblast growth factor receptor substrate 2 participates in vascular endothelial growth factor-induced signaling

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FRS2 alpha attenuates FGF receptor signaling by Grb2-mediated recruitment of the ubiquitin ligase Cbl.

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7 January 2021

Direct interaction of Rnd1 with FRS2 beta regulates Rnd1-induced down-regulation of RhoA activity and is involved in fibroblast growth factor-induced neurite outgrowth in PC12 cells

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7 January 2021

Identifiers

DOI

10.1038/CR.2009.95

1 reference

14 September 2017

1 reference