(Q39827200)

English

The enhancement of Raf-1 kinase activity by knockdown of Spry2 is associated with high sensitivity to paclitaxel in v-Ha-ras-transformed NIH 3T3 fibroblasts

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

The enhancement of Raf-1 kinase activity by knockdown of Spry2 is associated with high sensitivity to paclitaxel in v-Ha-ras-transformed NIH 3T3 fibroblasts (English)

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

1 reference

based on heuristic

inferred from title

author name string

Jun-Ho Ahn

1

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

Ki-Hwan Eum

2

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

Michael Lee

3

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

publication date

9 July 2009

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

Molecular and Cellular Biochemistry

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

332

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

1-2

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

189-197

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

https://scigraph.springernature.com/pub.10.1007/s11010-009-0191-5

0 references

Identification of tumor-specific paclitaxel (Taxol)-responsive regulatory elements in the interleukin-8 promoter

1 reference

https://api.crossref.org/works/10.1007%2FS11010-009-0191-5

21 January 2018

Inhibition of phosphorylation of BAD and Raf-1 by Akt sensitizes human ovarian cancer cells to paclitaxel

1 reference

https://pubmed.ncbi.nlm.nih.gov/19588231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Raf-1 kinase activation is uncoupled from downstream MEK/ERK pathway in cells treated with Src tyrosine kinase inhibitor PP2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19588231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vinblastine-induced phosphorylation of Bcl-2 and Bcl-XL is mediated by JNK and occurs in parallel with inactivation of the Raf-1/MEK/ERK cascade

1 reference

https://pubmed.ncbi.nlm.nih.gov/19588231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Id-1-induced Raf/MEK pathway activation is essential for its protective role against taxol-induced apoptosis in nasopharyngeal carcinoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19588231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A signal transduction pathway for activation of the mdr1 promoter involves the proto-oncogene c-raf kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/19588231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Raf-1 kinase activity predicts for paclitaxel resistance in TP53mut, but not TP53wt human ovarian cancer cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19588231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Do beta-tubulin mutations have a role in resistance to chemotherapy?

1 reference

https://pubmed.ncbi.nlm.nih.gov/19588231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Taxanes, microtubules and chemoresistant breast cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19588231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mammalian Sprouty4 suppresses Ras-independent ERK activation by binding to Raf1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19588231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epigenetic inactivation of the human sprouty2 (hSPRY2) homologue in prostate cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19588231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of cancer drug resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/19588231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

sprouty encodes a novel antagonist of FGF signaling that patterns apical branching of the Drosophila airways

1 reference

https://pubmed.ncbi.nlm.nih.gov/19588231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of sprouty 2 inhibits HGF/SF-mediated cell growth, invasion, migration, and cytokinesis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19588231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Src tyrosine kinase inhibitor PP2 markedly enhances Ras-independent activation of Raf-1 protein kinase by phorbol myristate acetate and H2O2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19588231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel angiogenic signaling pathways and vascular targets

1 reference

https://pubmed.ncbi.nlm.nih.gov/19588231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Embryonic lethality and fetal liver apoptosis in mice lacking the c-raf-1 gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/19588231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Roles of the RAF/MEK/ERK and PI3K/PTEN/AKT pathways in malignant transformation and drug resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/19588231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sprouty2 inhibits the Ras/MAP kinase pathway by inhibiting the activation of Raf.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19588231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel role of Sprouty 2 in regulating cellular apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19588231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of beta-tubulin isotypes in resistance to antimitotic drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/19588231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High Raf-1 kinase activity protects human tumor cells against paclitaxel-induced cytotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/19588231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sprouty 2 regulates DNA damage-induced apoptosis in Ras-transformed human fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/19588231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Raf kinase inhibitory protein regulates aurora B kinase and the spindle checkpoint

1 reference

https://pubmed.ncbi.nlm.nih.gov/19588231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of angiogenesis by a mouse sprouty protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/19588231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of Raf/MEK/ERK kinase activity does not affect the chemoresistance profile of advanced prostate cancer cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19588231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Taxol and 10-deacetylbaccatinIII induce distinct changes in the dynamics of caveolae

1 reference

https://pubmed.ncbi.nlm.nih.gov/19588231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Resistance to Taxol in lung cancer cells associated with increased microtubule dynamics

1 reference

https://pubmed.ncbi.nlm.nih.gov/19588231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synergistic anti-tumoral effect of paclitaxel (Taxol)+AS101 in a murine model of B16 melanoma: association with ras-dependent signal-transduction pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/19588231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Single cell gel/comet assay: guidelines for in vitro and in vivo genetic toxicology testing

1 reference

https://pubmed.ncbi.nlm.nih.gov/19588231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sprouty 2, an inhibitor of mitogen-activated protein kinase signaling, is down-regulated in hepatocellular carcinoma.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19588231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of signalling by Sprouty: a developing story

1 reference

https://pubmed.ncbi.nlm.nih.gov/19588231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of four chemotherapy regimens for advanced non-small-cell lung cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/19588231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of Taxol-induced cell death are concentration dependent.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19588231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Down-regulation of Raf-1 kinase is associated with paclitaxel resistance in human breast cancer MCF-7/Adr cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19588231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Raf-1 and Bcl-2 induce distinct and common pathways that contribute to breast cancer drug resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/19588231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Taxol induces bcl-2 phosphorylation and death of prostate cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19588231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase II Trial of Taxol, an Active Drug in the Treatment of Metastatic Breast Cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/19588231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeting microtubules for cancer chemotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/19588231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mammalian sprouty proteins inhibit cell growth and differentiation by preventing ras activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19588231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Raf-1/bcl-2 phosphorylation: a step from microtubule damage to cell death.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19588231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular effects of paclitaxel: myths and reality (a critical review).

1 reference

https://pubmed.ncbi.nlm.nih.gov/19588231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Taxol induction of p21WAF1 and p53 requires c-raf-1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19588231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The complexity of Raf-1 regulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19588231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Taxol-induced apoptosis and phosphorylation of Bcl-2 protein involves c-Raf-1 and represents a novel c-Raf-1 signal transduction pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/19588231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/19588231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Taxol: a unique antineoplastic agent with significant activity in advanced ovarian epithelial neoplasms

1 reference

https://pubmed.ncbi.nlm.nih.gov/19588231

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11010-009-0191-5

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

15 September 2017

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