(Q39828329)

15 September 2017

P-21-activated protein kinase-1 functions as a linker between insulin and Wnt signaling pathways in the intestine (English)

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15 September 2017

J Sun

1

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15 September 2017

S Khalid

2

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15 September 2017

M Rozakis-Adcock

3

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15 September 2017

I G Fantus

4

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15 September 2017

T Jin

5

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15 September 2017

language of work or name

English

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publication date

6 July 2009

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15 September 2017

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15 September 2017

28

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15 September 2017

3132-3144

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15 September 2017

35

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https://scigraph.springernature.com/pub.10.1038/onc.2009.167

15 September 2017

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cites work

beta-catenin is a target for the ubiquitin-proteasome pathway

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

Regulation of microfilament reorganization and invasiveness of breast cancer cells by kinase dead p21-activated kinase-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

Epigenetic inactivation of the Wnt antagonist DICKKOPF-1 (DKK-1) gene in human colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

Phosphorylation of the ErbB3 binding protein Ebp1 by p21-activated kinase 1 in breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

Functional interaction of beta-catenin with the transcription factor LEF-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

Linking colorectal cancer to Wnt signaling

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.167

Pak-1 expression increases with progression of colorectal carcinomas to metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

Pyruvate inhibits zinc-mediated pancreatic islet cell death and diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

P21-activated protein kinase is overexpressed in hepatocellular carcinoma and enhances cancer metastasis involving c-Jun NH2-terminal kinase activation and paxillin phosphorylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

Adenomatous polyposis coli/beta-catenin interaction and downstream targets: altered gene expression in gastrointestinal tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

Wnt breakers in colon cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

PAK1 primes MEK1 for phosphorylation by Raf-1 kinase during cross-cascade activation of the ERK pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

Wnt induction of chondrocyte hypertrophy through the Runx2 transcription factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

A synthetic inhibitor of the mitogen-activated protein kinase cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

Rac-PAK signaling stimulates extracellular signal-regulated kinase (ERK) activation by regulating formation of MEK1-ERK complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

PAK1 interacts with beta-catenin and is required for the regulation of the beta-catenin signalling pathway by gastrins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

Identification of c-MYC as a target of the APC pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

Phosphorylation of beta-catenin by cyclic AMP-dependent protein kinase stabilizes beta-catenin through inhibition of its ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

Complex formation of adenomatous polyposis coli gene product and axin facilitates glycogen synthase kinase-3 beta-dependent phosphorylation of beta-catenin and down-regulates beta-catenin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

Beta-catenin mutations in cell lines established from human colorectal cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

TSC2 integrates Wnt and energy signals via a coordinated phosphorylation by AMPK and GSK3 to regulate cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

p21-activated Kinase 1 (Pak1)-dependent phosphorylation of Raf-1 regulates its mitochondrial localization, phosphorylation of BAD, and Bcl-2 association

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

Wnt and beyond Wnt: multiple mechanisms control the transcriptional property of beta-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

The protein kinase Pak3 positively regulates Raf-1 activity through phosphorylation of serine 338

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

p21-activated kinase (PAK1) is phosphorylated and activated by 3-phosphoinositide-dependent kinase-1 (PDK1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

Lessons from hereditary colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

The p21Rac/Cdc42-activated kinases (PAKs).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

Diabetes mellitus publication patterns, 1984-2005.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

Oncogenic K-ras stimulates Wnt signaling in colon cancer through inhibition of GSK-3beta.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

Glucagon-like peptide-1 activation of TCF7L2-dependent Wnt signaling enhances pancreatic beta cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

Target genes of beta-catenin-T cell-factor/lymphoid-enhancer-factor signaling in human colorectal carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

MEK1 activation by PAK: a novel mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

Insulin-like growth factor 1 regulates the location, stability, and transcriptional activity of beta-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

APC mutations occur early during colorectal tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

Insulin-like growth factor-1 regulates endogenous RUNX2 activity in endothelial cells through a phosphatidylinositol 3-kinase/ERK-dependent and Akt-independent signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

Insulin and wnt1 pathways cooperate to induce reserve cell activation in differentiation and myotube hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

PAK1 phosphorylation of MEK1 regulates fibronectin-stimulated MAPK activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

PAK1-mediated activation of ERK1/2 regulates lamellipodial dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

Both Wnt and mTOR signaling pathways are involved in insulin-stimulated proto-oncogene expression in intestinal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

Adhesion stimulates direct PAK1/ERK2 association and leads to ERK-dependent PAK1 Thr212 phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

Kinase-deficient Pak1 mutants inhibit Ras transformation of Rat-1 fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

A role for Pak protein kinases in Schwann cell transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

The Akt proto-oncogene links Ras to Pak and cell survival signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

Phosphorylation of beta-catenin by cyclic AMP-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

Insulin activates a p21-activated kinase in muscle cells via phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

The POU homeodomain protein OCT3 as a potential transcriptional activator for fibroblast growth factor-4 (FGF-4) in human breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

TCF-4 mediates cell type-specific regulation of proglucagon gene expression by beta-catenin and glycogen synthase kinase-3beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

Cross talk between the insulin and Wnt signaling pathways: evidence from intestinal endocrine L cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

Involvement of alpha-PAK-interacting exchange factor in the PAK1-c-Jun NH(2)-terminal kinase 1 activation and apoptosis induced by benzo[a]pyrene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

A Phosphatidylinositol 3-kinase-regulated Akt-independent signaling promotes cigarette smoke-induced FRA-1 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

Akt Phosphorylation of Serine 21 on Pak1 Modulates Nck Binding and Cell Migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

Protein shuttles, IGF-I and colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

Hyperinsulinaemia and hyperglycaemia: possible risk factors of colorectal cancer among diabetic patients

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

Insulin and IGF-1 stimulate the beta-catenin pathway through two signalling cascades involving GSK-3beta inhibition and Ras activation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

Type 2 Diabetes Mellitus: The Impact on Colorectal Adenoma Risk in Women

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

Insulin, insulin-like growth factors and colon cancer: a review of the evidence

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

Metabolic syndrome, hyperinsulinemia, and colon cancer: a review

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

Function of the Rho family GTPases in Ras-stimulated Raf activation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

A prospective study of plasma C-peptide and colorectal cancer risk in men

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.167

31 March 2020

Identifiers

DOI

10.1038/ONC.2009.167

1 reference

release_cvpi3m5ce5h5xpxpop46zmgfjy

15 September 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/cvpi3m5ce5h5xpxpop46zmgfjy

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference