(Q39832953)

15 September 2017

title

TNF-like weak inducer of apoptosis inhibits proinflammatory TNF receptor-1 signaling (English)

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15 September 2017

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10

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15 September 2017

Martin Ehrenschwender

object named as

M Ehrenschwender

4

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author name string

A Wicovsky

1

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15 September 2017

S Salzmann

2

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15 September 2017

C Roos

3

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15 September 2017

T Rosenthal

5

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15 September 2017

D Siegmund

6

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15 September 2017

F Henkler

7

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15 September 2017

F Gohlke

8

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15 September 2017

C Kneitz

9

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15 September 2017

publication date

26 June 2009

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Cell Death & Differentiation

15 September 2017

published in

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15 September 2017

volume

16

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15 September 2017

issue

11

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15 September 2017

page(s)

1445-1459

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https://scigraph.springernature.com/pub.10.1038/cdd.2009.80

15 September 2017

exact match

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cites work

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The Fn14 cytoplasmic tail binds tumour-necrosis-factor-receptor-associated factors 1, 2, 3 and 5 and mediates nuclear factor-kappaB activation

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TWEAK induces NF-kappaB2 p100 processing and long lasting NF-kappaB activation.

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TWEAK mediates signal transduction and differentiation of RAW264.7 cells in the absence of Fn14/TweakR. Evidence for a second TWEAK receptor

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TWEAK/Fn14 interaction regulates RANTES production, BMP-2-induced differentiation, and RANKL expression in mouse osteoblastic MC3T3-E1 cells

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TWEAKing tissue remodeling by a multifunctional cytokine: role of TWEAK/Fn14 pathway in health and disease

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Ion-channel-forming colicins

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Studies on the interaction between TWEAK and the death receptor WSL-1/TRAMP (DR3)

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The mitogen-inducible Fn14 gene encodes a type I transmembrane protein that modulates fibroblast adhesion and migration

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A novel TNF receptor family member binds TWEAK and is implicated in angiogenesis

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TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1-TRAF2 complex to sensitize tumor cells to TNFalpha.

21 January 2018

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The Fn14 immediate-early response gene is induced during liver regeneration and highly expressed in both human and murine hepatocellular carcinomas

21 January 2018

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TWEAK induces liver progenitor cell proliferation

21 January 2018

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Anti-TWEAK monoclonal antibodies reduce immune cell infiltration in the central nervous system and severity of experimental autoimmune encephalomyelitis.

21 January 2018

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TWEAK, via its receptor Fn14, is a novel regulator of mesenchymal progenitor cells and skeletal muscle regeneration

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Tumor necrosis factor-like weak inducer of apoptosis inhibits skeletal myogenesis through sustained activation of nuclear factor-kappaB and degradation of MyoD protein.

21 January 2018

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TRAF2 and TRAF3 signal adapters act cooperatively to control the maturation and survival signals delivered to B cells by the BAFF receptor.

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Critical roles of TRAF2 and TRAF5 in tumor necrosis factor-induced NF-kappa B activation and protection from cell death

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Early lethality, functional NF-kappaB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice

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Inhibition of death receptor-mediated gene induction by a cycloheximide-sensitive factor occurs at the level of or upstream of Fas-associated death domain protein (FADD)

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TWEAK can induce cell death via endogenous TNF and TNF receptor 1.

21 January 2018

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Multiple pathways of TWEAK-induced cell death

21 January 2018

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Death of HT29 adenocarcinoma cells induced by TNF family receptor activation is caspase-independent and displays features of both apoptosis and necrosis

21 January 2018

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Identification of RIP1 kinase as a specific cellular target of necrostatins

21 January 2018

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Tumor necrosis factor receptor-associated factor (TRAF) 1 regulates CD40-induced TRAF2-mediated NF-kappaB activation

21 January 2018

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TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways

21 January 2018

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TRAF1 is a TNF inducible regulator of NF-kappaB activation.

21 January 2018

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Caspase-mediated cleavage converts the tumor necrosis factor (TNF) receptor-associated factor (TRAF)-1 from a selective modulator of TNF receptor signaling to a general inhibitor of NF-kappaB activation

21 January 2018

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Tumor therapeutics by design: targeting and activation of death receptors

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The tumor necrosis factor receptor 2 signal transducers TRAF2 and c-IAP1 are components of the tumor necrosis factor receptor 1 signaling complex

21 January 2018

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NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation

21 January 2018

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Ubiquitination and translocation of TRAF2 is required for activation of JNK but not of p38 or NF-kappaB.

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2009.80

TNF-alpha induced c-IAP1/TRAF2 complex translocation to a Ubc6-containing compartment and TRAF2 ubiquitination

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2009.80

Tumor necrosis factor receptor 2 signaling induces selective c-IAP1-dependent ASK1 ubiquitination and terminates mitogen-activated protein kinase signaling

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2009.80

TNF-RII and c-IAP1 mediate ubiquitination and degradation of TRAF2

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2009.80

CD30-dependent degradation of TRAF2: implications for negative regulation of TRAF signaling and the control of cell survival

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2009.80

De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2009.80

Ubiquitination of RIP Is Required for Tumor Necrosis Factor α-induced NF-κB Activation

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2009.80

Activation of IKK by TNFalpha requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO

21 January 2018

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Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation [corrected]

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2009.80

cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2009.80

c-IAP1 and c-IAP2 are critical mediators of tumor necrosis factor alpha (TNFalpha)-induced NF-kappaB activation

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2009.80

TRAF6 deficiency promotes TNF-induced cell death through inactivation of GSK3beta

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2009.80

TRAF2 phosphorylation modulates tumor necrosis factor alpha-induced gene expression and cell resistance to apoptosis

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2009.80

An antiapoptotic protein, c-FLIPL, directly binds to MKK7 and inhibits the JNK pathway

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2009.80

Translocation of TRAF proteins regulates apoptotic threshold of cells

21 January 2018

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The TWEAK-Fn14 cytokine-receptor axis: discovery, biology and therapeutic targeting

21 January 2018

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No end in site: TWEAK/Fn14 activation and autoimmunity associated- end-organ pathologies

21 January 2018

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TWEAK and the central nervous system

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2009.80

Permanent cell line expressing human factor VIII-related antigen established by hybridization

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2009.80

Highly efficient gene transfer into baboon marrow repopulating cells using GALV-pseudotype oncoretroviral vectors produced by human packaging cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.80

The extracellular domains of FasL and Fas are sufficient for the formation of supramolecular FasL-Fas clusters of high stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.80

Regulation of TNFR1 and CD95 signalling by receptor compartmentalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.80

Noncanonical NF-kappaB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.80

Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-kappaB signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.80

Identification of a ligand for the death-domain-containing receptor Apo3

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.80

7 January 2021

TWEAK shall inherit the earth

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.80

7 January 2021

TWEAK is a novel arthritogenic mediator

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.80

7 January 2021

The human tumor necrosis factor (TNF) receptor-associated factor 1 gene (TRAF1) is up-regulated by cytokines of the TNF ligand family and modulates TNF-induced activation of NF-kappaB and c-Jun N-terminal kinase

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.80

7 January 2021

Identification and characterization of two CD40-inducible enhancers in the mouse TRAF1 gene locus

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.80

7 January 2021

A crucial role for p80 TNF-R2 in amplifying p60 TNF-R1 apoptosis signals in T lymphocytes

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.80

7 January 2021

Identifiers

DOI

10.1038/CDD.2009.80

1 reference

15 September 2017

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