(Q39834578)

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Adenovirally mediated p53 overexpression diversely influence the cell cycle of HEp-2 and CAL 27 cell lines upon cisplatin and methotrexate treatment.

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1 February 2020

Adenovirally mediated p53 overexpression diversely influence the cell cycle of HEp-2 and CAL 27 cell lines upon cisplatin and methotrexate treatment (English)

1 reference

Europe PubMed Central

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1 February 2020

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Sandra Kraljević Pavelić

1

1 reference

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1 February 2020

Marko Marjanović

2

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1 February 2020

4

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Marijeta Kralj

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1 February 2020

author name string

Miroslav Poznić

3

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1 February 2020

publication date

23 June 2009

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1 February 2020

Journal of Cancer Research and Clinical Oncology

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1 February 2020

135

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1 February 2020

12

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1 February 2020

1747-1761

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1 February 2020

https://scigraph.springernature.com/pub.10.1007/s00432-009-0621-5

0 references

Effects of cisplatin on expression of DNA ligases in MiaPaCa human pancreatic cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19548002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

To die or not to die: how does p53 decide?

1 reference

https://pubmed.ncbi.nlm.nih.gov/19548002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A reversible, p53-dependent G0/G1 cell cycle arrest induced by ribonucleotide depletion in the absence of detectable DNA damage.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19548002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p21WAF1/CIP1 is more effective than p53 in growth suppression of mouse renal carcinoma cell line Renca in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/19548002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of G1/S transition potentiates oxaliplatin-induced cell death in colon cancer cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/19548002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure and growth-dependent regulation of the human cyclin B1 promoter

1 reference

https://pubmed.ncbi.nlm.nih.gov/19548002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pivotal role of the cyclin-dependent kinase inhibitor p21WAF1/CIP1 in apoptosis and autophagy

1 reference

https://pubmed.ncbi.nlm.nih.gov/19548002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p53 regulates a G2 checkpoint through cyclin B1

1 reference

https://pubmed.ncbi.nlm.nih.gov/19548002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA damage-induced expression of p53 suppresses mitotic checkpoint kinase hMps1: the lack of this suppression in p53MUT cells contributes to apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19548002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of cyclin-dependent kinase 2 by p21 is necessary for retinoblastoma protein-mediated G1 arrest after gamma-irradiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19548002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cisplatin-induced growth arrest of head and neck cancer cells correlates with increased expression of p16 and p53.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19548002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of p53 and caspase 3 activity on cell death and senescence in response to methotrexate in the breast tumor cell

1 reference

https://pubmed.ncbi.nlm.nih.gov/19548002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The p53 response to DNA damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/19548002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Atypical cytostatic mechanism of N-1-sulfonylcytosine derivatives determined by in vitro screening and computational analysis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19548002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Restoration of p53 function leads to tumour regression in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/19548002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adenovirus-mediated p53 gene therapy in osteosarcoma cell lines: sensitization to cisplatin and doxorubicin

1 reference

https://pubmed.ncbi.nlm.nih.gov/19548002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of CDK activity and PCNA-dependent DNA replication by p21 is blocked by interaction with the HPV-16 E7 oncoprotein

1 reference

https://pubmed.ncbi.nlm.nih.gov/19548002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TP53 status and taxane-platinum versus platinum-based therapy in ovarian cancer patients: a non-randomized retrospective study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19548002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of the cyclin-dependent kinase inhibitor p21 in apoptosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19548002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New functional activities for the p21 family of CDK inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/19548002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p53 — Master and Commander

1 reference

https://pubmed.ncbi.nlm.nih.gov/19548002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Administration of wild-type p53 adenoviral vector synergistically enhances the cytotoxicity of anti-cancer drugs in human lung cancer cells irrespective of the status of p53 gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/19548002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Outcomes of p53 activation--spoilt for choice

1 reference

https://pubmed.ncbi.nlm.nih.gov/19548002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adenovirus-mediated p53 gene therapy: overview of preclinical studies and potential clinical applications

1 reference

https://pubmed.ncbi.nlm.nih.gov/19548002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The dark side of a tumor suppressor: anti-apoptotic p53.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19548002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

WAF1, a potential mediator of p53 tumor suppression

1 reference

https://pubmed.ncbi.nlm.nih.gov/19548002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adenovirus p53 gene therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/19548002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synergistic effects of adenovirus expressing wild-type p53 on chemosensitivity of non-small cell lung cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19548002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The tumour suppressor protein p53 can repress transcription of cyclin B.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19548002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Current status of gendicine in China: recombinant human Ad-p53 agent for treatment of cancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/19548002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Requirement for p53 and p21 to sustain G2 arrest after DNA damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/19548002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeting the checkpoint kinases: chemosensitization versus chemoprotection

1 reference

https://pubmed.ncbi.nlm.nih.gov/19548002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Degradation of cyclin B is required for the onset of anaphase in Mammalian cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19548002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p21-Mediated nuclear retention of cyclin B1-Cdk1 in response to genotoxic stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/19548002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical implications of p53 mutations

1 reference

https://pubmed.ncbi.nlm.nih.gov/19548002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disruption of p53 in human cancer cells alters the responses to therapeutic agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/19548002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

P53: an ubiquitous target of anticancer drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/19548002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Wild-type p53: tumors can't stand it.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19548002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p53-oriented cancer therapies: current progress

1 reference

https://pubmed.ncbi.nlm.nih.gov/19548002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The individualization of cancer therapy: the unexpected role of p53.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19548002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Growing clinical evidence for the interaction of the p53 genotype and response to induction chemotherapy in advanced non-small cell lung cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/19548002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of the efficacy of 7-hydroxystaurosporine (UCN-01) and other staurosporine analogs to abrogate cisplatin-induced cell cycle arrest in human breast cancer cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/19548002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

P53 tumor suppressor gene therapy for cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/19548002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cisplatin chemotherapy plus adenoviral p53 gene therapy in EBV-positive and -negative nasopharyngeal carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/19548002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of p21(Waf-1) in regulating the G1 and G2/M checkpoints in ultraviolet-irradiated keratinocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19548002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endogenous p21WAF1/CIP1 status predicts the response of human tumor cells to wild-type p53 and p21WAF1/CIP1 overexpression

1 reference

https://pubmed.ncbi.nlm.nih.gov/19548002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p21 is necessary for the p53-mediated G1 arrest in human cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19548002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Somatic point mutations in the p53 gene of human tumors and cell lines: updated compilation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19548002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation of a human cyclin cDNA: evidence for cyclin mRNA and protein regulation in the cell cycle and for interaction with p34cdc2

1 reference

https://pubmed.ncbi.nlm.nih.gov/19548002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Temporal and spatial control of cyclin B1 destruction in metaphase

1 reference

https://pubmed.ncbi.nlm.nih.gov/19548002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Repression of cyclin B1 expression after treatment with adriamycin, but not cisplatin in human lung cancer A549 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19548002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A dual role of p21waf1/cip1 gene in apoptosis of HEp-2 treated with cisplatin or methotrexate.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19548002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proliferation, cell cycle and apoptosis in cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/19548002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Constitutive expression of E2F-1 leads to p21-dependent cell cycle arrest in S phase of the cell cycle

1 reference

https://pubmed.ncbi.nlm.nih.gov/19548002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00432-009-0621-5

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19548002%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19548002%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

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