(Q39835313)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27099176%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

title

Lentiviral hematopoietic stem cell gene therapy for X-linked severe combined immunodeficiency (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27099176%20AND%20SRC:MED&resulttype=core&format=json

severe combined immunodeficiency

2 April 2020

main subject

gene therapy

0 references

1 reference

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27099176%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Geraldine M O'Connor

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27099176%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Harry Malech

28

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27099176%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

20

Luigi D Notarangelo

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27099176%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

1

Suk See De Ravin

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27099176%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

17

Douglas Kuhns

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27099176%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

8

Uimook Choi

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27099176%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

23

Elizabeth Kang

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27099176%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

7

Narda Theobald

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27099176%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

29

Lela Kardava

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27099176%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

author name string

Xiaolin Wu

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27099176%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Nana Kwatemaa

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27099176%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Patricia Littel

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27099176%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Ling Su

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27099176%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Martha Marquesen

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27099176%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Dianne Hilligoss

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27099176%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Janet Lee

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27099176%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Clarissa M Buckner

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27099176%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Daniel McVicar

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27099176%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Robert E Throm

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27099176%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Sheng Zhou

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27099176%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

I Celine Hanson

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27099176%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Mort J Cowan

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27099176%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Coleen Hadigan

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27099176%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Michael Meagher

25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27099176%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

John T Gray

26

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27099176%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Brian P Sorrentino

27

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27099176%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Susan Moir

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27099176%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Sandra Anaya-O'Brien

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27099176%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

language of work or name

English

0 references

publication date

1 April 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27099176%20AND%20SRC:MED&resulttype=core&format=json

Science Translational Medicine

2 April 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27099176%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

volume

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27099176%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

issue

335

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27099176%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

page(s)

335ra57

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27099176%20AND%20SRC:MED&resulttype=core&format=json

A modified γ-retrovirus vector for X-linked severe combined immunodeficiency

2 April 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5557273

Severe cutaneous human papillomavirus infection associated with natural killer cell deficiency following stem cell transplantation for severe combined immunodeficiency

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5557273

Mobilization characteristics and strategies to improve hematopoietic progenitor cell mobilization and collection in patients with chronic granulomatous disease and severe combined immunodeficiency

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5557273

Transplantation outcomes for severe combined immunodeficiency, 2000-2009.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5557273

HIV latency. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5557273

Enhancers are major targets for murine leukemia virus vector integration

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5557273

Lentiviral hematopoietic stem cell gene therapy benefits metachromatic leukodystrophy

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5557273

Lentiviral hematopoietic stem cell gene therapy in patients with Wiskott-Aldrich syndrome.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5557273

Mouse transplant models for evaluating the oncogenic risk of a self-inactivating XSCID lentiviral vector

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5557273

Transduction of human CD34+ repopulating cells with a self-inactivating lentiviral vector for SCID-X1 produced at clinical scale by a stable cell line.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5557273

Gene therapy for adenosine deaminase-deficient severe combined immune deficiency: clinical comparison of retroviral vectors and treatment plans.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5557273

The host genomic environment of the provirus determines the abundance of HTLV-1-infected T-cell clones

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5557273

Transfusion independence and HMGA2 activation after gene therapy of human β-thalassaemia

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5557273

Efficacy of gene therapy for X-linked severe combined immunodeficiency

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5557273

A self-inactivating lentiviral vector for SCID-X1 gene therapy that does not activate LMO2 expression in human T cells

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5557273

Long-term clinical outcome of patients with severe combined immunodeficiency who received related donor bone marrow transplants without pretransplant chemotherapy or post-transplant GVHD prophylaxis

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5557273

Efficient construction of producer cell lines for a SIN lentiviral vector for SCID-X1 gene therapy by concatemeric array transfection

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5557273

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5557273

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5557273

Insertional mutagenesis combined with acquired somatic mutations causes leukemogenesis following gene therapy of SCID-X1 patients

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5557273

Vector integration is nonrandom and clustered and influences the fate of lymphopoiesis in SCID-X1 gene therapy

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5557273

Gene therapy improves immune function in preadolescents with X-linked severe combined immunodeficiency

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5557273

Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5557273

LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5557273

Transcription start regions in the human genome are favored targets for MLV integration

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5557273

Differential expression of CD21 identifies developmentally and functionally distinct subsets of human transitional B cells.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5557273

Hematopoietic stem cell gene therapy for adenosine deaminase deficient-SCID.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5557273

Gene therapy for immunodeficiency due to adenosine deaminase deficiency.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5557273

Long-term outcome after hematopoietic stem cell transplantation of a single-center cohort of 90 patients with severe combined immunodeficiency

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5557273

Failure of SCID-X1 gene therapy in older patients

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5557273

A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5557273

10.1126/SCITRANSLMED.AAD8856

20 August 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27099176%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27099176%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

1 reference