(Q39839629)

15 September 2017

Role of amyloid-beta glycine 33 in oligomerization, toxicity, and neuronal plasticity (English)

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15 September 2017

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2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6665404&resulttype=core&format=json

15 May 2020

Lisa M Munter

4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6665404&resulttype=core&format=json

15 May 2020

author name string

Anja Harmeier

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6665404&resulttype=core&format=json

15 May 2020

Benjamin R Rost

3

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15 May 2020

Haiqing Hua

5

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15 May 2020

Oleg Georgiev

6

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15 May 2020

Michael Beyermann

7

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15 May 2020

Peter W Hildebrand

8

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15 May 2020

Christoph Weise

9

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15 May 2020

Walter Schaffner

10

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15 May 2020

Dietmar Schmitz

11

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15 May 2020

Gerd Multhaup

12

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15 May 2020

language of work or name

English

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publication date

1 June 2009

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15 September 2017

Journal of Neuroscience

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6665404&resulttype=core&format=json

15 May 2020

volume

29

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15 May 2020

issue

23

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15 May 2020

page(s)

7582-7590

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6665404&resulttype=core&format=json

Early phenotypic changes in transgenic mice that overexpress different mutants of amyloid precursor protein in brain

15 May 2020

cites work

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12 December 2020

Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models

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12 December 2020

Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease

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12 December 2020

High-level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation

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12 December 2020

Oligomerizaiton and fibril asssembly of the amyloid-beta protein.

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12 December 2020

Electrostatics of nanosystems: application to microtubules and the ribosome

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12 December 2020

Soluble oligomers of beta amyloid (1-42) inhibit long-term potentiation but not long-term depression in rat dentate gyrus.

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12 December 2020

Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases

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12 December 2020

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

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12 December 2020

A beta 25-35-induced depression of long-term potentiation in area CA1 in vivo and in vitro is attenuated by verapamil

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12 December 2020

Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

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12 December 2020

Alzheimer beta-amyloid homodimers facilitate A beta fibrillization and the generation of conformational antibodies

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12 December 2020

Alzheimer's disease-affected brain: presence of oligomeric A beta ligands (ADDLs) suggests a molecular basis for reversible memory loss

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12 December 2020

Mapping abeta amyloid fibril secondary structure using scanning proline mutagenesis

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12 December 2020

Cortical synaptic integration in vivo is disrupted by amyloid-beta plaques.

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12 December 2020

A model for studying Alzheimer's Abeta42-induced toxicity in Drosophila melanogaster

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12 December 2020

Analysis of the secondary structure of beta-amyloid (Abeta42) fibrils by systematic proline replacement

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12 December 2020

Natural oligomers of the amyloid-beta protein specifically disrupt cognitive function

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12 December 2020

Longer forms of amyloid beta protein: implications for the mechanism of intramembrane cleavage by gamma-secretase.

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12 December 2020

Structural role of glycine in amyloid fibrils formed from transmembrane alpha-helices

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12 December 2020

Amyloid beta protein immunotherapy neutralizes Abeta oligomers that disrupt synaptic plasticity in vivo.

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12 December 2020

On the nucleation of amyloid beta-protein monomer folding

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12 December 2020

Dendritic spine abnormalities in amyloid precursor protein transgenic mice demonstrated by gene transfer and intravital multiphoton microscopy

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12 December 2020

gamma-Cleavage is dependent on zeta-cleavage during the proteolytic processing of amyloid precursor protein within its transmembrane domain

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12 December 2020

Transmembrane glycine zippers: physiological and pathological roles in membrane proteins

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12 December 2020

The GROMOS software for biomolecular simulation: GROMOS05.

1 reference

12 December 2020

Scanning cysteine mutagenesis analysis of Abeta-(1-40) amyloid fibrils

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12 December 2020

3D structure of Alzheimer's amyloid-beta(1-42) fibrils

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12 December 2020

Alanine scanning mutagenesis of Abeta(1-40) amyloid fibril stability

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12 December 2020

Inhibitors of amyloid toxicity based on beta-sheet packing of Abeta40 and Abeta42.

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12 December 2020

Generic hydrophobic residues are sufficient to promote aggregation of the Alzheimer's Abeta42 peptide

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12 December 2020

AMPAR removal underlies Abeta-induced synaptic depression and dendritic spine loss

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12 December 2020

Impairments of hippocampal synaptic plasticity induced by aggregated beta-amyloid (25-35) are dependent on stimulation-protocol and genetic background.

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12 December 2020

GxxxG motifs within the amyloid precursor protein transmembrane sequence are critical for the etiology of Abeta42.

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12 December 2020

Natural oligomers of the Alzheimer amyloid-beta protein induce reversible synapse loss by modulating an NMDA-type glutamate receptor-dependent signaling pathway

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12 December 2020

Familial Alzheimer's disease mutations alter the stability of the amyloid beta-protein monomer folding nucleus

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12 December 2020

Structural reorganisation and potential toxicity of oligomeric species formed during the assembly of amyloid fibrils

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12 December 2020

Lipids revert inert Abeta amyloid fibrils to neurotoxic protofibrils that affect learning in mice

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12 December 2020

Homophilic interactions of the amyloid precursor protein (APP) ectodomain are regulated by the loop region and affect beta-secretase cleavage of APP.

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12 December 2020

Amyloidogenic processing but not amyloid precursor protein (APP) intracellular C-terminal domain production requires a precisely oriented APP dimer assembled by transmembrane GXXXG motifs

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12 December 2020

Amyloid beta protein dimer-containing human CSF disrupts synaptic plasticity: prevention by systemic passive immunization

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12 December 2020

Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

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12 December 2020

Amyloid beta-protein assembly and Alzheimer disease

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12 December 2020

Amyloid-beta peptide (Abeta) neurotoxicity is modulated by the rate of peptide aggregation: Abeta dimers and trimers correlate with neurotoxicity

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12 December 2020

Subcellular localization and dimerization of APLP1 are strikingly different from APP and APLP2.

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12 December 2020

Cellular prion protein mediates impairment of synaptic plasticity by amyloid-beta oligomers

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12 December 2020

Neurotoxicity of a fragment of the amyloid precursor associated with Alzheimer's disease

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12 December 2020

Sevenless and Drosophila eye development: a tyrosine kinase controls cell fate

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12 December 2020

Aggregation of secreted amyloid beta-protein into sodium dodecyl sulfate-stable oligomers in cell culture

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12 December 2020

Secondary structure of amyloid beta peptide correlates with neurotoxic activity in vitro

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12 December 2020

Seeding "one-dimensional crystallization" of amyloid: a pathogenic mechanism in Alzheimer's disease and scrapie?

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12 December 2020

Morphology and toxicity of Abeta-(1-42) dimer derived from neuritic and vascular amyloid deposits of Alzheimer's disease.

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12 December 2020

A single-point slight alteration set as a tool for structure-activity relationship studies of ovine corticotropin releasing factor.

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12 December 2020

Reduced surface: an efficient way to compute molecular surfaces

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12 December 2020

The role of A beta 42 in Alzheimer's disease

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12 December 2020

10.1523/JNEUROSCI.1336-09.2009

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6665404&resulttype=core&format=json

15 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6665404&resulttype=core&format=json

15 May 2020

1 reference