(Q39841334)

15 September 2017

title

Emodin enhances gefitinib-induced cytotoxicity via Rad51 downregulation and ERK1/2 inactivation (English)

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15 September 2017

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ChEBI release 2020-05-28

Ruey-Shyang Chen

1

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15 September 2017

Jhih-Yuan Jhan

2

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15 September 2017

Ying-Jhen Su

3

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15 September 2017

Wei-Ting Lee

4

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15 September 2017

Chao-Min Cheng

5

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15 September 2017

Shih-Ci Ciou

6

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15 September 2017

Szu-Ting Lin

7

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15 September 2017

Show-Mei Chuang

8

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15 September 2017

Jen-Chung Ko

9

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15 September 2017

Yun-Wei Lin

10

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15 September 2017

language of work or name

English

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publication date

6 June 2009

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Experimental Cell Research

15 September 2017

published in

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15 September 2017

volume

315

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15 September 2017

issue

15

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15 September 2017

page(s)

2658-2672

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Epidermal growth factor-related peptides and their receptors in human malignancies

15 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.002

EGF receptor as a therapeutic target: patient selection and mechanisms of resistance to receptor-targeted drugs.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.002

Epidermal growth factor receptor tyrosine kinase as a target for anticancer therapy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.002

Untangling the ErbB signalling network

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.002

Heterodimerization and functional interaction between EGF receptor family members: a new signaling paradigm with implications for breast cancer research

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.002

Epidermal growth factor receptor tyrosine kinase inhibitors as anticancer agents

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.002

The epidermal growth factor receptor as a target for cancer therapy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.002

Multi-institutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer (The IDEAL 1 Trial) [corrected].

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.002

Efficacy of gefitinib, an inhibitor of the epidermal growth factor receptor tyrosine kinase, in symptomatic patients with non-small cell lung cancer: a randomized trial

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.002

Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.002

Epidermal growth factor receptor activation: how exon 19 and 21 mutations changed our understanding of the pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.002

The structures of antioxidant and cytotoxic agents from natural source: anthraquinones and tannins from roots of Rumex patientia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.002

Immune reponses in human mesangial cells regulated by emodin from Polygonum hypoleucum Ohwi

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.002

Phytoestrogens from the roots of Polygonum cuspidatum (Polygonaceae): structure-requirement of hydroxyanthraquinones for estrogenic activity.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.002

Emodin inhibits TNF-alpha-induced human aortic smooth-muscle cell proliferation via caspase- and mitochondrial-dependent apoptosis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.002

Emodin induces apoptosis in human lung adenocarcinoma cells through a reactive oxygen species-dependent mitochondrial signaling pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.002

Tyrosine kinase inhibitors, emodin and its derivative repress HER-2/neu-induced cellular transformation and metastasis-associated properties.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.002

Emodin induces apoptosis in human promyeloleukemic HL-60 cells accompanied by activation of caspase 3 cascade but independent of reactive oxygen species production

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.002

Emodin-induced apoptosis through p53-dependent pathway in human hepatoma cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.002

Emodin induces apoptosis through caspase 3-dependent pathway in HK-2 cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.002

Antimutagenicity and cytotoxicity of the constituents from the aerial parts of Rumex acetosa

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.002

Elevated recombination in immortal human cells is mediated by HsRAD51 recombinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.002

Role of the human RAD51 protein in homologous recombination and double-stranded-break repair

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.002

Over-expression of wild-type Rad51 correlates with histological grading of invasive ductal breast cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.002

RAD51, genomic stability, and tumorigenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.002

Fusion tyrosine kinases induce drug resistance by stimulation of homology-dependent recombination repair, prolongation of G(2)/M phase, and protection from apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.002

Homologous recombinational repair vis-à-vis chlorambucil resistance in chronic lymphocytic leukemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.002

High-level expression of Rad51 is an independent prognostic marker of survival in non-small-cell lung cancer patients

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.002

Combined evaluation of Rad51 and ERCC1 expressions for sensitivity to platinum agents in non-small cell lung cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.002

In vitro and in vivo potentiation of radiosensitivity of malignant gliomas by antisense inhibition of the RAD51 gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.002

Involvement of Rad51 in cytotoxicity induced by epidermal growth factor receptor inhibitor (gefitinib, IressaR) and chemotherapeutic agents in human lung cancer cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.002

Basis for effective combination cancer chemotherapy with antimetabolites

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.002

Baseline gene expression predicts sensitivity to gefitinib in non-small cell lung cancer cell lines.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.002

Role of repair protein Rad51 in regulating the response to gefitinib in human non-small cell lung cancer cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.002

Isolation and inhibitory activity against ERK phosphorylation of hydroxyanthraquinones from rhubarb.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.002

The role of celecoxib in Rad51 expression and cell survival affected by gefitinib in human non-small cell lung cancer cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.002

Emodin suppresses interleukin-1beta induced mesangial cells proliferation and extracellular matrix production via inhibiting P38 MAPK.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.002

Emodin enhances arsenic trioxide-induced apoptosis via generation of reactive oxygen species and inhibition of survival signaling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.002

Defective DNA Strand Break Repair after DNA Damage in Prostate Cancer Cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.002

p53 modulates homologous recombination by transcriptional regulation of the RAD51 gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.002

BCR/ABL regulates mammalian RecA homologs, resulting in drug resistance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.002

The replacement of ATP by the competitive inhibitor emodin induces conformational modifications in the catalytic site of protein kinase CK2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.002

Cilostazol enhances casein kinase 2 phosphorylation and suppresses tumor necrosis factor-alpha-induced increased phosphatase and tensin homolog deleted from chromosome 10 phosphorylation and apoptotic cell death in SK-N-SH cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.002

Gemcitabine sensitization by checkpoint kinase 1 inhibition correlates with inhibition of a Rad51 DNA damage response in pancreatic cancer cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.002

Targeting homologous recombination using imatinib results in enhanced tumor cell chemosensitivity and radiosensitivity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.002

Radiation-induced assembly of Rad51 and Rad52 recombination complex requires ATM and c-Abl

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.002

In vitro cytotoxic effects of imatinib in combination with anticancer drugs in human prostate cancer cell lines.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.06.002

10.1016/J.YEXCR.2009.06.002

7 January 2021

Identifiers

DOI

1 reference

15 September 2017

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