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Spatial sequestration and detoxification of Huntingtin by the ribosome quality control complex.
scientific article published on April 2016
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PMCID
4868537
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27033550%20AND%20SRC:MED&resulttype=core&format=json
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31 March 2020
title
Spatial sequestration and detoxification of Huntingtin by the ribosome quality control complex
(English)
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Europe PubMed Central
PMCID
4868537
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27033550%20AND%20SRC:MED&resulttype=core&format=json
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31 March 2020
main subject
quality control
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Junsheng Yang
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1
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4868537
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31 March 2020
Beidong Liu
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4
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PMCID
4868537
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31 March 2020
Thomas Nyström
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5
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4868537
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31 March 2020
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Xinxin Hao
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2
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4868537
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31 March 2020
Xiuling Cao
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3
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4868537
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31 March 2020
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1 April 2016
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4868537
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31 March 2020
published in
eLife
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4868537
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31 March 2020
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31 March 2020
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CZ Software Mentions: A large dataset of software mentions in the biomedical literature
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cites work
Structure and assembly pathway of the ribosome quality control complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4868537
retrieved
22 September 2017
Protein synthesis. Rqc2p and 60S ribosomal subunits mediate mRNA-independent elongation of nascent chains
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4868537
retrieved
22 September 2017
HSF-1-mediated cytoskeletal integrity determines thermotolerance and life span
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4868537
retrieved
22 September 2017
Prion-like proteins sequester and suppress the toxicity of huntingtin exon 1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4868537
retrieved
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1 reference
stated in
PubMed Central
reference URL
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retrieved
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1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4868537
retrieved
22 September 2017
Polyglutamine-rich suppressors of huntingtin toxicity act upstream of Hsp70 and Sti1 in spatial quality control of amyloid-like proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4868537
retrieved
22 September 2017
Glutathione peroxidase activity is neuroprotective in models of Huntington's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4868537
retrieved
22 September 2017
Heat shock response activation exacerbates inclusion body formation in a cellular model of Huntington disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4868537
retrieved
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PolyQ proteins interfere with nuclear degradation of cytosolic proteins by sequestering the Sis1p chaperone
1 reference
stated in
PubMed Central
reference URL
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retrieved
22 September 2017
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1 reference
stated in
PubMed Central
reference URL
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retrieved
22 September 2017
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1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4868537
retrieved
22 September 2017
A ribosome-bound quality control complex triggers degradation of nascent peptides and signals translation stress
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4868537
retrieved
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1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4868537
retrieved
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1 reference
stated in
PubMed Central
reference URL
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retrieved
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Huntington's disease: from molecular pathogenesis to clinical treatment
1 reference
stated in
PubMed Central
reference URL
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retrieved
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Role of a ribosome-associated E3 ubiquitin ligase in protein quality control
1 reference
stated in
PubMed Central
reference URL
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retrieved
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1 reference
stated in
PubMed Central
reference URL
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retrieved
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1 reference
stated in
PubMed Central
reference URL
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retrieved
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A mouse forward genetics screen identifies LISTERIN as an E3 ubiquitin ligase involved in neurodegeneration
1 reference
stated in
PubMed Central
reference URL
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retrieved
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1 reference
stated in
PubMed Central
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retrieved
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The BioGRID Interaction Database: 2008 update
1 reference
stated in
PubMed Central
reference URL
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retrieved
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1 reference
stated in
PubMed Central
reference URL
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retrieved
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Critical role of the proline-rich region in Huntingtin for aggregation and cytotoxicity in yeast.
1 reference
stated in
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reference URL
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retrieved
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1 reference
stated in
PubMed Central
reference URL
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retrieved
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Flanking sequences profoundly alter polyglutamine toxicity in yeast
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4868537
retrieved
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1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4868537
retrieved
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1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4868537
retrieved
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1 reference
stated in
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reference URL
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retrieved
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1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4868537
retrieved
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1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4868537
retrieved
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1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4868537
retrieved
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1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4868537
retrieved
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1 reference
stated in
PubMed Central
reference URL
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retrieved
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1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4868537
retrieved
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1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4868537
retrieved
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1 reference
stated in
PubMed Central
reference URL
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retrieved
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1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4868537
retrieved
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1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4868537
retrieved
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1 reference
stated in
PubMed Central
reference URL
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retrieved
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1 reference
stated in
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retrieved
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1 reference
stated in
PubMed Central
reference URL
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retrieved
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1 reference
stated in
PubMed Central
reference URL
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retrieved
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1 reference
stated in
PubMed Central
reference URL
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retrieved
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1 reference
stated in
PubMed Central
reference URL
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retrieved
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1 reference
stated in
PubMed Central
reference URL
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retrieved
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1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4868537
retrieved
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1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4868537
retrieved
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1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4868537
retrieved
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1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4868537
retrieved
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1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4868537
retrieved
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1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4868537
retrieved
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1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/27033550
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
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1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/27033550
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Detection of ubiquitylated proteins in yeast
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/27033550
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.7554/ELIFE.11792
1 reference
stated in
Europe PubMed Central
PMCID
4868537
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27033550%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 March 2020
PMCID
4868537
1 reference
stated in
Europe PubMed Central
PMCID
4868537
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27033550%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 March 2020
PubMed ID
27033550
1 reference
stated in
Europe PubMed Central
PMCID
4868537
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27033550%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 March 2020
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