(Q33609884)

28 July 2017

title

Polyglutamine-rich suppressors of huntingtin toxicity act upstream of Hsp70 and Sti1 in spatial quality control of amyloid-like proteins (English)

1 reference

28 July 2017

0 references

Philipp Trepte

3

0 references

author name string

Katie J Wolfe

series ordinal

1

1 reference

28 July 2017

Hong Yu Ren

series ordinal

2

1 reference

28 July 2017

Douglas M Cyr

series ordinal

4

1 reference

28 July 2017

language of work or name

English

0 references

publication date

14 May 2014

1 reference

28 July 2017

1 reference

28 July 2017

volume

9

1 reference

28 July 2017

issue

5

1 reference

28 July 2017

page(s)

e95914

1 reference

Creative Commons Attribution 4.0 International

28 July 2017

copyright license

start time

14 May 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4020751/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Abnormal proteins can form aggresome in yeast: aggresome-targeting signals and components of the machinery

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Absence of behavioral abnormalities and neurodegeneration in vivo despite widespread neuronal huntingtin inclusions

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21 June 2018

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Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death

21 June 2018

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A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4020751

21 June 2018

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0095914

Caspase cleavage of mutant huntingtin precedes neurodegeneration in Huntington's disease.

21 January 2018

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The Saccharomyces cerevisiae Mob2p-Cbk1p kinase complex promotes polarized growth and acts with the mitotic exit network to facilitate daughter cell-specific localization of Ace2p transcription factor

21 June 2018

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Huntington toxicity in yeast model depends on polyglutamine aggregation mediated by a prion-like protein Rnq1

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4020751

Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's disease

21 June 2018

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21 June 2018

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21 June 2018

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Impairment of the ubiquitin-proteasome system by protein aggregation

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4020751

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21 June 2018

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21 June 2018

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The Hsc70 co-chaperone CHIP targets immature CFTR for proteasomal degradation

21 June 2018

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A census of glutamine/asparagine-rich regions: implications for their conserved function and the prediction of novel prions

21 June 2018

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21 June 2018

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Hsp70 and hsp40 chaperones can inhibit self-assembly of polyglutamine proteins into amyloid-like fibrils

21 June 2018

1 reference

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Inhibiting caspase cleavage of huntingtin reduces toxicity and aggregate formation in neuronal and nonneuronal cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4020751

Self-assembly of polyglutamine-containing huntingtin fragments into amyloid-like fibrils: implications for Huntington's disease pathology

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4020751

Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4020751

Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4020751

21 June 2018

Conformational disease

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21 June 2018

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21 June 2018

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21 June 2018

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Two differentially regulated mRNAs with different 5' ends encode secreted with intracellular forms of yeast invertase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4020751

Mutant huntingtin promotes the fibrillogenesis of wild-type huntingtin: a potential mechanism for loss of huntingtin function in Huntington's disease

21 June 2018

1 reference

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Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0095914

Chaperonin TRiC promotes the assembly of polyQ expansion proteins into nontoxic oligomers.

21 January 2018

1 reference

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Expanded polyglutamine protein forms nuclear inclusions and causes neural degeneration in Drosophila

21 January 2018

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Nuclear targeting of mutant Huntingtin increases toxicity

21 January 2018

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Global changes to the ubiquitin system in Huntington's disease.

21 January 2018

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Identification of genes that modify ataxin-1-induced neurodegeneration.

21 January 2018

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Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0095914

Cross-seeding fibrillation of Q/N-rich proteins offers new pathomechanism of polyglutamine diseases

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0095914

Oligoproline effects on polyglutamine conformation and aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0095914

Huntington aggregates may not predict neuronal death in Huntington's disease

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4020751

Rnq1: an epigenetic modifier of protein function in yeast

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24828240

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A toxic monomeric conformer of the polyglutamine protein

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24828240

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0095914

1 reference

28 July 2017

0 references

1 reference

28 July 2017

1 reference