(Q39875864)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27030752%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

title

Overexpression of Dyrk1A, a Down Syndrome Candidate, Decreases Excitability and Impairs Gamma Oscillations in the Prefrontal Cortex (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27030752%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

1 reference

1 reference

1

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31 March 2020

Maria Martinez de Lagran

2

1 reference

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31 March 2020

Maurizio Mattia

3

1 reference

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31 March 2020

Patricia Castano-Prat

4

1 reference

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31 March 2020

Lorena Perez-Mendez

5

1 reference

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31 March 2020

Thomas Gener

7

1 reference

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31 March 2020

Jordi Garcia-Ojalvo

9

1 reference

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31 March 2020

José M Delgado-García

11

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Maria Victoria Sanchez-Vives

31 March 2020

12

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31 March 2020

Mara Dierssen Sotos

13

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31 March 2020

author name string

Laura Ciria-Suarez

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27030752%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

Belen Sancristobal

8

1 reference

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31 March 2020

Agnès Gruart

10

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31 March 2020

language of work or name

English

0 references

publication date

1 March 2016

1 reference

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31 March 2020

published in

Journal of Neuroscience

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31 March 2020

volume

36

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31 March 2020

issue

13

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31 March 2020

page(s)

3648-3659

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describes a project that uses

31 March 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6601739/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Neurodevelopmental delay, motor abnormalities and cognitive deficits in transgenic mice overexpressing Dyrk1A (minibrain), a murine model of Down's syndrome.

1 reference

12 December 2020

Dyrk1A haploinsufficiency affects viability and causes developmental delay and abnormal brain morphology in mice

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12 December 2020

Dyrk1A expression pattern supports specific roles of this kinase in the adult central nervous system

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What determines the frequency of fast network oscillations with irregular neural discharges? I. Synaptic dynamics and excitation-inhibition balance

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Cellular and network mechanisms of slow oscillatory activity (<1 Hz) and wave propagations in a cortical network model

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Synchronization in networks of excitatory and inhibitory neurons with sparse, random connectivity.

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Motor phenotypic alterations in TgDyrk1a transgenic mice implicate DYRK1A in Down syndrome motor dysfunction

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Sleep-wake architecture in mouse models for Down syndrome

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Cognitive tasks augment gamma EEG power.

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Inhibitory postsynaptic potentials carry synchronized frequency information in active cortical networks.

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Alterations in the phenotype of neocortical pyramidal cells in the Dyrk1A+/- mouse

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12 December 2020

Involvement of the CA3-CA1 synapse in the acquisition of associative learning in behaving mice.

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12 December 2020

Cognitive executive function in Down's syndrome.

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12 December 2020

Voltage dependence of NMDA-activated macroscopic conductances predicted by single-channel kinetics.

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Synaptic mechanisms of synchronized gamma oscillations in inhibitory interneuron networks

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12 December 2020

Are corticothalamic 'up' states fragments of wakefulness?

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12 December 2020

Sleep and EEG features in genetic models of Down syndrome

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12 December 2020

Truncation of the Down syndrome candidate gene DYRK1A in two unrelated patients with microcephaly

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12 December 2020

E-I balance and human diseases - from molecules to networking.

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12 December 2020

Increased anxiety-like behavior in mice lacking the inhibitory synapse cell adhesion molecule neuroligin 2

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12 December 2020

Spontaneous high-frequency (10-80 Hz) oscillations during up states in the cerebral cortex in vitro

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Inter-hemispheric functional coupling of eyes-closed resting EEG rhythms in adolescents with Down syndrome.

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12 December 2020

Theoretical exploration of the neural bases of behavioural disinhibition, apathy and executive dysfunction in preclinical Alzheimer's disease in people with Down's syndrome: potential involvement of multiple frontal-subcortical neuronal circuits.

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12 December 2020

Mirrored bilateral slow-wave cortical activity within local circuits revealed by fast bihemispheric voltage-sensitive dye imaging in anesthetized and awake mice.

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12 December 2020

Inhibitory modulation of cortical up states.

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12 December 2020

Multiple origins of the cortical γ rhythm

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12 December 2020

MNB/DYRK1A as a multiple regulator of neuronal development

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12 December 2020

Intragenic deletion in DYRK1A leads to mental retardation and primary microcephaly.

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12 December 2020

Regional slow waves and spindles in human sleep

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12 December 2020

Cognitive impairment and EEG background activity in adults with Down's syndrome: a topographic study.

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12 December 2020

Down syndrome children often have brain with maturation delay, retardation of growth, and cortical dysgenesis.

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12 December 2020

Slow oscillations orchestrating fast oscillations and memory consolidation.

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12 December 2020

Slow and fast rhythms generated in the cerebral cortex of the anesthetized mouse.

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12 December 2020

Dyrk1A influences neuronal morphogenesis through regulation of cytoskeletal dynamics in mammalian cortical neurons.

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12 December 2020

Spectral fingerprints of large-scale neuronal interactions

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12 December 2020

Mechanisms of gamma oscillations

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12 December 2020

Increased sleep fragmentation leads to impaired off-line consolidation of motor memories in humans

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12 December 2020

The DYRK1A gene is a cause of syndromic intellectual disability with severe microcephaly and epilepsy

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12 December 2020

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12 December 2020

A biophysical observation model for field potentials of networks of leaky integrate-and-fire neurons

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12 December 2020

Making waves: initiation and propagation of corticothalamic Ca2+ waves in vivo

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12 December 2020

Exploring the spectrum of dynamical regimes and timescales in spontaneous cortical activity

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12 December 2020

Epigallocatechin-3-gallate, a DYRK1A inhibitor, rescues cognitive deficits in Down syndrome mouse models and in humans

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12 December 2020

Prefrontal deficits in a murine model overexpressing the down syndrome candidate gene dyrk1a.

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12 December 2020

Obstructive sleep apnea syndrome and cognition in Down syndrome.

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12 December 2020

Excitation/inhibition balance and learning are modified by Dyrk1a gene dosage.

1 reference

12 December 2020

Anomalous brain functional connectivity contributing to poor adaptive behavior in Down syndrome.

1 reference

12 December 2020

DYRK1A haploinsufficiency causes a new recognizable syndrome with microcephaly, intellectual disability, speech impairment, and distinct facies

1 reference

12 December 2020

A new cognitive evaluation battery for Down syndrome and its relevance for clinical trials

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12 December 2020

Sleep patterns in mental retardation: Down's syndrome

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12 December 2020

Selective neuroanatomic abnormalities in Down's syndrome and their cognitive correlates: evidence from MRI morphometry.

1 reference

12 December 2020

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1 reference

12 December 2020

A novel slow (< 1 Hz) oscillation of neocortical neurons in vivo: depolarizing and hyperpolarizing components

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12 December 2020

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12 December 2020

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12 December 2020

Exact numerical simulation of the Ornstein-Uhlenbeck process and its integral

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10.1523/JNEUROSCI.2517-15.2016

Identifiers

DOI

1 reference

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31 March 2020

1 reference

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31 March 2020

1 reference